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Causative gene of a rare disorder discovered by sequencing only protein-coding regions of genome

For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder.

Tips from the journals of the American Society for Microbiology

Genes May Determine Susceptibility to H5N1 Avian Influenza A Virus Infection

Rhesus macaque moms 'go gaga' for baby, too

The intense exchanges that human mothers share with their newborn infants may have some pretty deep roots, suggests a study of rhesus macaques reported online on October 8th in Current Biology, a Cell Press publication.

Visionary concept earns La Jolla Institute scientist prestigious NIH Pioneer Award

SAN DIEGO -- (September 24, 2009) A scientist at the La Jolla Institute for Allergy & Immunology has received one of the National Institutes of Health (NIH)'s top awards -- the 2009 NIH Director's Pioneer Award.

Tuberculosis patients can reduce transmissability by inhaling interferon through a nebulizer

New York, NY (September 14, 2009): A new study published in the September 15, 2009, issue of PLoS ONE found that patients with cavitary pulmonary tuberculosis receiving anti-TB medications supplemented with nebulized interferon-gamma have fewer bacilli in the lungs and less inflammation, thereby reducing the transmissibility of tuberculosis in the early phase of treatment.

Scientists discover mechanism to make existing antibiotics more effective at lower doses

New York, NY (September 10, 2009): A new study published in the September 11, 2009 issue of Science by researchers at the NYU School of Medicine reveals a conceptually novel mechanism that plays an important role in making human pathogens like Staphylococcus aureus and Bacillus anthracis resistant to numerous antibiotics. The study led by Evgeny A.

Why Obama's dog has curly hair

SALT LAKE CITY, Aug. 27, 2009 -- University of Utah researchers used data from Portuguese water dogs -- the breed of President Barack Obama's dog Bo -- to help find a gene that gives some dogs curly hair and others long, wavy hair.

Brain response to information about the future suggests that ignorance isn't bliss

New research demonstrates that single neurons in the reward center of the brain process not only primitive rewards but also more abstract, cognitive rewards related to the quest for information about the future.

Study shows PET can measure effectiveness of novel breast cancer treatment

RESTON, Va. -- A new study published in the July issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET) scans in mice can be used to determine whether a novel type of breast cancer treatment is working as intended.

STAT3 protein found to play a key role in cancer

New York, June 25, 2009 -- A protein called STAT3 has been found to play a fundamental role in converting normal cells to cancerous cells, according to a new study led by David E. Levy, Ph.D., professor of pathology and microbiology at NYU Langone Medical Center.

Out-of-pocket health-care costs rise for workers with employer coverage

Bethesda, MD -- The 161 million Americans with employer-sponsored health insurance are facing substantial increases in out-of-pocket (OOP) costs, according to a study published today on the Health Affairs Web site.

New MR technique may help save women from unnecessary breast biopsies

A new MR procedure that uses diffusion-weighted imaging (DWI) to determine whether or not a breast lesion is malignant or benign may help reduce unnecessary breast biopsies, according to a study performed at the National Institute of Health in Bethesda, MD. DWI is a method that produces images detecting the exchange of water molecules between tissue compartments (diffusion).

Airborne asthma allergens

A survey of airborne fungi and fungal spores found in Eastern Puerto Rico suggests that certain species may be a major cause of the high incidence of childhood asthma in this part of the world.

Alcohol researchers relate a genetic factor to anxiety in women

Researchers have identified a genetic factor that appears to influence anxiety in women. Combining DNA analysis, recordings of brain activity, and psychological tests, investigators at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) found that Caucasian and American Indian women with the same gene variant had similarly high scores on tests that measure anxiety. These women also had similar electroencephelograms (EEG) -- recordings of brain electrical activity as unique as an individual's fingerprints -- that showed characteristics of anxious temperament, further strengthening the association of this shared genetic factor with anxiety. The study appears in the current issue of the journal Psychiatric Genetics.

Stem Cells in Blood a Possible Indicator of Heart Disease Risk

Levels of a type of adult stem cell in the bloodstream may indicate a person's risk of developing cardiovascular disease, according to a study supported by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health in Bethesda, MD.



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