Effective mentoring critical to HIV/AIDS research efforts
An innovative mentoring program at the UCSF-Gladstone Institute for Virology and Immunology Center for AIDS Research is providing vital support for the development of the next generation of HIV/AIDS researchers and clinician scientists.
Described in an article published in the American Journal for Public Health appearing February 26 in the First Look section of the AJPH website, the program focuses on overcoming challenges faced by early-career investigators through several novel mechanisms.
"One key innovation adopted in our program is 'trans' mentoring. In this model, a mentee is paired with a mentor from a research discipline different from the mentee's. For instance, a mentee working in basic science is paired with a mentor who is doing either clinical or behavioral research. One advantage is to lessen potential conflicts of interest between mentee and mentor. Additionally, an important benefit in that it strongly encourages multidisciplinary research," said the article's co-author James S. Kahn, MD, UCSF professor of clinical medicine and co-director of the UCSF-GIVI CFAR's mentoring program.
One of the goals of the CFAR mentoring program is to support and create pathways for multidisciplinary HIV research. The three broad categories that mentors and mentees are divided into are basic research, clinical or translational research, and population or behavioral research.
Another significant innovation in the CFAR program lies in considering the role of the mentor.
"In the past, senior investigators mentored junior researchers without really considering what was necessary for successful mentoring. Our concept is that mentoring is a teachable skill. We focus on and help develop the specific skill set needed by a mentor to best assist an early-career investigator," said Kahn.
Open mentoring is an innovation that the CFAR mentoring program uses to support its goal of retaining early-career investigators and optimizing their productivity. Open mentoring is a strategy that provides mentoring to persons desiring mentoring and is contrasted with elite mentoring in which mentoring is provided to those investigators who have achieved early success.
"Deciding to reserve mentoring for the top strata of early-career researchers does not broaden the pool of investigators. By making mentoring open to any investigator doing HIV research, we find that we are providing career support to a more diverse group of individuals from a more diverse set of research disciplines," said the article's co-author, Ruth M. Greenblatt, MD, UCSF professor of clinical medicine and co-director of the CFAR mentoring program.
The authors note other goals of the mentoring program, including retaining early-career investigators and optimizing their productivity and assisting them with transitions as their careers progress.
"The National Institutes of Health is limiting grant resubmissions due to funding constraints. Our mentors assist in optimizing grant submissions and ensuring mentees have a strong career strategy with appropriate expectations. Moreover, mentoring can be extremely helpful in assisting early-career investigators with the complicated but essential balancing of personal time with career advancement," said Greenblatt.
Greenblatt observed that the NIH has placed particular emphasis on the challenges faced by clinician scientists and noted that the country risks losing an entire generation of these essential investigators.
"We hear similar concerns from clinician scientists. They mention lack of access to funding, lack of caring for them as individuals and lack of a collegial atmosphere. Our mentoring serves as an intervention to specifically address these problems," said Greenblatt.
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February 26, 2009
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Comments
how
March 23, 2009 by Anonymous, 35 weeks 2 days ago
Comment: 35533
how can i get a hold of this stuff it might actually work sab4747@hotmail.com
CURE for HIV/AIDS....Ambush
February 27, 2009 by Anonymous, 38 weeks 5 days ago
Comment: 34901
THE CURE for HIV/AIDS.......AMBUSH
THE IDEA that AMBUSH cures AIDS
is being proven by the more than 400 individuals who have taken a dose of 60 ml three times daily for 21 days. The result is that AMBUSH 'KILLS' the virus by causing the protein envelope to rupture and the viral particles are discarded by the white blood cells. AMBUSH is able to 'KILL' the virus that are 'hiding' in the lymph system by its 'natural radioactive' properties. This process allows the body to 'return to normal health' with a corresponding immunity to that or those strains of the virus.
What is AMBUSH ?
AMBUSH is a radioactive isotope of uranium that is found in the 'palm' plant of which there are more than 3000 species. When ingested, AMBUSH causes the body temperature in the trunk area to rise to about 102 degrees when the individual is sleeping. The preparation takes four hours per batch, which is then given to the individuals for consumption 60 ml three times daily for 21 days. AMBUSH is a herbal preparation in this form but it contains an active ingredient which is a 'NEW' crystalline substance, a drug from the 'palm plant' similarly to ASPIRIN originating from the willow tree bark
RESULTS:
After 21 days on AMBUSH, ALL the individuals experienced a decrease in viral load to undetectable, an increase in cd4, increase in RBC, an improvement in general health such as more color to the face, decrease in Buffalo hump, an increase in gluteal muscles, a decrease to having no joint pains whereby individuals can bend to touch their toes, and walk up steps are but a few examples. There is also a dramatic increase in their sexual appetite beginning after the first week of therapy
DISCUSSION:
In any plant concoction such as percolated 'tea', there are 30-40,000 compounds, whi ch would take the scientific community twenty years to isolate one particular ingredient if they knew what they were looking for. The LORD GOD has given me seven steps to isolate the active ingredient, which is soft and metallic in nature and has a carbon- uranium-sulfur-(classified)-phentolamine configuration or structure. This is similar to Federick Kekule and the discovery of the benzene ring where he dreamt the structure.
As an antiviral and 'natural radioactivity' producing agent, AMBUSH is also effective against leukemia, lupus and HPV. Here I am saying that I have 'GIVEN' AMBUSH in the same 'strength' and dosage to patients with leukemia, lupus and HPV. A 35 year old male with HIV found it difficult to impossible to urinate was put on 'green tea' and water while the doctors contemplated prostrate surgery. One of the doctors gave him my number , I sent him a supply of AMBUSH an d he has not been given any more ARV's, since taking AMBUSH 18 months ago, is in 'good' health and has expressed a willingness to be examined by HIV investigators like many others who have taken AMBUSH.
I have sent this 'IDEA' to most HIV research agencies, scientist of the field, universities, hospitals, clinics, politicians and news agencies to which it is REJECTED because the name of THE LORD GOD is mentioned. He has steered me scientifically through the processes such as which plant and how to produce the active ingredient. What are the odds of a Florida Pharmacist picking a plant would contain the CURE for HIV/AIDS ?
I have never charged any of the people for their supply of AMBUSH but a life saving has been spent on the project with NO renumeration from any sources because AMBUSH falls outside the walls of modern medicine and research.
PROPOSAL:
My proposal is that I PROVE that AMBUSH CURES HIV/AIDS by giving it to a number of END-STAGE or DRUG-RESISTANT people and the scientific community watches their recovery. This proposal addresses the problem in that I have already outlaid the results to be obtained.
This IDEA is unconventional in that the scientific community has rejected AMBUSH because I say it is GOD given. Secondly if I wrote it according to certain standards, then it might be peer reviewed. However, THE LORD GOD has also shown me that there are five enzyme systems associated with the virus, reverse transcriptase, protease, fusion and two more of which causes the virus to be AIRBOURNE. This means that without DIVINE intervention mankind and ALL warm- blooded mammals will be extinct in a number of years.
The PROOF of what I am saying is found in scientific papers wherein it is found that when the protease cuts the viral strands, it cuts it at DIFFERENT lengths EVERY time, to which it should always be a valine at the end but is a different amino acid every time. This is why it is IMPOSSIBLE to produce a VACCINE.
Since this is NOT a hypothesis but there are about 400 individuals who have taken AMBUSH, here lies a vast area in which to check, recheck and confirm that AMBUSH CURES AIDS. Let it be mentioned that during the HIV reproductive cycle, reverse transcriptase converts viral RNA into DNA compatible to human genetic materials. Thus the human DNA has been 'hijacked' and since each person has a DIFFERENT DNA, then the new viral copy is unique to that person which shows that each individual has a DIFFERENT STRAIN of the virus. Consider two HIV positive people swapping viral strains and increasing its complexity with multiple partners.
It can also be proposed that they be revisited as proof that the strain or strains that they had were 'killed' at the time of taking AMBUSH considering that a person can catch as many different strains as there are people who are infected by HIV.
I am also willing to work with the scientific community in identifying those individuals who took AMBUSH and wish to be identified with this process notwithstanding that some are stigmatized while others are jubilant,
Once AMBUSH is verified as being able to accomplish that which is aforementioned then the next stage might be the natural and artificial synthesis of the substance.
Finally, if this is accepted or not, believed or not, THE LORD GOD always wins and this is the heavenly truth to which AMBUSH was divinely given to mankind for the CURE of HIV/AIDS and it will be here forever. Apostle Shada Mishe.
apostleshadamishe@gmail.com
Here is a video taped presentation that I gave at t he Martin Luther King library in Washington
http://www.youtube.com/watch?v=8V53D1w__Po
http://www.youtube.com/watch?v=vPwuwlVBOV0
http://www.youtube.com/watch?v=ZejptOwMTzQ
http://www.youtube.com/watch?v=CqcTgIAhrhc
http://www.youtube.com/watch?v=f7HPKcT_iwY
http://www.youtube.com/watch?v=W9iQfgiYAnw
http://www.youtube.com/watch?v=i3RzRS6tJDM
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