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Activated stem cells in damaged lungs could be first step toward cancer

DURHAM, N.C. ? Stem cells that respond after a severe injury in the lungs of mice may be a source of rapidly dividing cells that lead to lung cancer, according to a team of American and British researchers.

Yeast missing sex genes undergo unexpected sexual reproduction

DURHAM, N.C. ?An emerging form of the pathogenic yeast Candida is able to complete a full sexual cycle in a test tube, even though it's missing the genes for reproduction. And it may also do so while infecting us, according to Duke University Medical Center researchers.

Large clinical trial finds pirfenidone may help lung function in IPF patients

A large, well-controlled, multi-national clinical trial program has demonstrated the effectiveness and safety of what may become the first FDA-approved medicine for idiopathic pulmonary fibrosis, or IPF.

Program focused on body, mind and spirit helps women with breast cancer cope

DURHAM, N.C. - Pathfinders, a program designed to care for the whole person -- body, mind and spirit -- has been found to help women with terminal cancer cope and improved their quality of life, according to a study led by researchers in the Duke Comprehensive Cancer Center.

Patient-centered approach to capturing data from cancer patients improves care and research

DURHAM, N.C. - Wireless, personal computers used by cancer patients to log their symptoms help improve the patients' care and further cancer research, according to a study led by researchers in the Duke Comprehensive Cancer Center.

Preclinical work shows how one gene causes severe mental retardation

Durham, N.C., and Chapel Hill, N.C. -- Researchers at Duke University Medical Center and the University of North Carolina have discovered in mice how a single disrupted gene can cause a form of severe mental retardation known as Angelman syndrome.

Women live longer, not better, largely because of obesity and arthritis

CHICAGO - Obesity and arthritis that take root during early and middle age significantly contribute to women's decreased quality of life during their senior years, according to researchers at Duke University Medical Center.

In a study that included 5,888 people over 65, women suffered up to two and a half times more disabilities than men of the same age.

A missing enzyme conveys major heart protection in pre-clinical work

DURHAM, N.C. - Mice born without a certain enzyme can resist the normal effects of a heart attack and retain nearly normal function in the heart's ventricles and still-oxygenated heart tissue, according to a study by researchers at Duke University Medical Center.

Drug-eluting stents found safe, superior to bare metal stents

DURHAM, NC - Drug-eluting stents were safe and superior to bare metal stents in preventing death and heart attacks among 262,700 "real-world" patients enrolled in a nationwide registry of cardiovascular disease, according to researchers from Duke University Medical Center.

Genetic irregularities linked to higher risk of COPD among smokers

DURHAM, N.C. - Scientists at Duke University Medical Center have discovered two genetic markers that appear to put some smokers at significantly higher risk of developing chronic obstructive pulmonary disease (COPD).

Studies show children can complete treatment for peanut allergies and achieve long-term tolerance

DURHAM, NC -- A carefully administered daily dose of peanuts has been so successful as a therapy for peanut allergies that a select group of children is now off treatment and eating peanuts daily, report doctors at Duke University Medical Center and Arkansas Children's Hospital.

New origin found for a critical immune response

DURHAM, N.C. - An immune system response that is critical to the first stages of fighting off viruses and harmful bacteria comes from an entirely different direction than most scientists had thought, according to a finding by researchers at the Duke University Medical Center.

Discovery Promises Simpler Therapy for Sickle Cell Disease

A new understanding of the causes for symptoms of sickle cell disease, a condition affecting one in every 600 African-Americans, has resulted from a study by researchers at Duke University Medical Center and Howard Hughes Medical Institute (HHMI). Their findings may lead to a new, more direct method for treating the disease, they said.

Monkeys will pay to look at porn

In a finding that deepens our understanding of animal social cognition, researchers at Duke University Medical Center have demonstrated for the first time that monkeys, like humans, value information according to its social content. People readily pay to see powerful or sexually attractive individuals, and, according to this new study, monkeys will also "pay" to view these kinds of images.

Both economics and evolutionary theory predict that animals should selectively acquire information about others that is most useful for guiding behavior. In most monkey social groups, behavior is structured by kinship, dominance, and reproductive status, suggesting that social information should be valued according to these attributes. While previous studies had shown that monkeys would work to see other monkeys, no one knew whether the value they placed on seeing other individuals was related to the social relevance of those individuals.

Epidemic of Liver Disease Linked to Obesity

One of the most serious results of overeating, a condition known as non-alcoholic fatty liver disease (NAFLD), is on the rise, according to gastroenterologists at Duke University Medical Center. While there is no confirmed cause of NAFLD, many experts believe that weight loss and increased physical activity are good starting points to help prevent or slow the progress of the condition. Anna Mae Diehl, chief of gastroenterology at Duke, said that NAFLD has become much more widespread as the obesity crisis has worsened.



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