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UCLA cancer researchers develop model that may help identify cancer stem cells

Researchers at UCLA's Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers.

Bee-killing parasite genome sequenced

Agricultural Research Service (ARS) scientists have sequenced the genome of a parasite that can kill honey bees. Nosema ceranae is one of many pathogens suspected of contributing to the current bee population decline, termed colony collapse disorder (CCD). Researchers describe the parasite's genome in a study published June 5 in the open-access journal PLoS Pathogens.

U-M researchers link pathway to breast cancer stem cells

ANN ARBOR, Mich. -- A gene well known to stop or suppress cancer plays a role in cancer stem cells, according to a new study from the University of Michigan Comprehensive Cancer Center. The researchers found that several pathways linked to the gene, called PTEN, also affected the growth of breast cancer stem cells.

Legal loophole exposes Canadians to drug advertising banned in US: UBC research

A legal loophole is counteracting Canada's ban on direct-to-consumer drug advertising and has exposed Canadians to more than $90 million worth of ads, including those for drugs with life-threatening risks, according to a study by UBC researchers.

In rare disease, a familiar protein disrupts gene function

An international team of scientists studying a rare genetic disease discovered that a bundle of proteins with the long-established function of keeping chromosomes together also plays an important role in regulating genes in humans.

OHSU researchers study the idling brain

PORTLAND, Ore - Oregon Health & Science University researchers, along with scientists at Washington University in St. Louis, are uncovering new information about the mind by studying the brain while it is at rest. It is believed this research will one day provide new tools for diagnosing mental health disorders and monitoring the progress of treatments.

Findings uncover new details about mysterious virus

WEST LAFAYETTE, Ind. - An international team of researchers has determined key structural features of the largest known virus, findings that could help scientists studying how the simplest life evolved and whether the unusual virus causes any human diseases.

Sugar on bacteria surface serves as base for a web of resistance

COLUMBUS, Ohio - The bacteria responsible for chronic infections in cystic fibrosis patients use one of the sugars on the germs' surface to start building a structure that helps the microbes resist

Einstein and Pitt researchers develop new TB test that will dramatically cut diagnosis time

March 19, 2009 - (BRONX, NY) - Researchers from the Albert Einstein College of Medicine and The University of Pittsburgh have developed an onsite method to quickly diagnose tuberculosis (TB) and expose the deadly drug-resistant strains that can mingle undetected with treatable TB strains.

Los Alamos researchers create 'map of science'

Los Alamos National Laboratory scientists have produced the world's first Map of Science--a high-resolution graphic depiction of the virtual trails scientists leave behind when they retrieve information from online services.

Small molecules block cancer gene

Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing gene to those of the small molecules, said a Baylor College of Medicine researcher in a report that appears in the current online issue of the journal PLoS One

Old men chasing young women: A good thing

It turns out that older men chasing younger women contributes to human longevity and the survival of the species, according to

Genes reveal new subspecies of tiger

An international group of researchers has found a new subspecies of tiger -- and they did it by delving into DNA rather than plunging into the jungle. A genetic analysis of tigers from across Asia revealed that tigers roaming the wilds of the Malaysian Peninsula are substantially different from those in the rest of the continent -- different enough to be considered a new subspecies. The finding, published today in the journal Public Library of Science Biology, could affect efforts to save the endangered cats.

Genetic glimpse of kidney shows how human cells age

For the first time, researchers at Stanford University School of Medicine have examined how kidneys change at a molecular level with the passage of time. What they found suggests that all human cells age in a similar way, supporting one theory about how cells grow old. ''Until now we really didn't know what happens when people get old,'' said Stuart Kim, PhD, professor of developmental biology and genetics, who led the study that is to be published in the November 30 issue of Public Library of Science Biology. ''Our work suggests that there's a common way for all tissues to get old.''

How wounds heal -- Clues from flies

Anyone who's endured their share of childhood scrapes has probably heard some version of the motherly admonishment, ''Don't pick that scab, you'll just make it worse!'' It turns out, Mom was on to something. Tissue damage in humans triggers a well-characterized response marked by rapid blood clotting and a recruitment of epidermal cells to the injury. When you remove a scab, you're also removing some of the newly regenerated tissues growing underneath, thereby interfering with the healing process. Many different cell types and proteins have been linked to the repair process, but the complexity of the mammalian wound response has challenged efforts to determine their individual roles.



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