Link between erectile dysfunction and obesity explored in obesity and weight management

New Rochelle, NY, August 24, 2009 -- Obese men are at increased risk for erectile dysfunction (ED), likely caused by atherosclerosis-related hypertension and cardiovascular disease, as well as hormonal changes associated with obesity, as described in a timely article published in Obesity and Weight Management, a journalzine published by Mary Ann Liebert, Inc. (www.liebertpub.com ). The article is available free online at www.liebertpub.com/owm

As many as 30-40% of men over the age of 50 may experience ED, and both obesity and physical inactivity may increase their risk. The build-up of atherosclerotic plaque in the arteries of obese men can damage the arterial lining and contribute to elevated blood pressure. In addition to atherosclerosis, the hormonal changes that accompany obesity, including lower testosterone, increase the risk of ED. The modifiable risk factors for heart disease, such as excess weight, diabetes, and hypertension, are generally the same as those for ED. Studies have shown that weight loss and increased physical activity can improve ED.

Adam Gilden Tsai, MD, MSCE, from the University of Colorado Denver, and David Sarwer, PhD, from the University of Pennsylvania School of Medicine, describe a 48-year-old man with mild obesity (weight = 197 lbs, body mass index = 32.6 kg/m2 ) and hypertension who suffers from ED in the article "Obesity and Erectile Dysfunction." Even with the use of ED medication (tadalafil, Cialis, Eli Lilly), he was not able to achieve an erection adequate for intercourse. After dietary counseling, a 4.6% weight reduction, and medication to lower his blood pressure to within the normal range (112/77 mm Hg), the patient has been able to achieve adequate erections with the use of ED medication as needed.

The authors emphasize that "the complicated interplay of weight and other health conditions relate to common medical symptoms, such as ED. We are reminded that atherosclerosis can cause not only macrovascular disease such as heart attack and stroke, but also microvascular disease, of which ED is one example."

"If you are looking for another reason to lose weight, research now suggests that erectile dysfunction can improve with weight loss," says James O. Hill, PhD, Editor-in-Chief of Obesity and Weight Management, Professor of Pediatrics and Medicine and Director of the Center for Human Nutrition and of the Colorado Clinical Nutrition Research Unit at the University of Colorado Denver.

Obesity and Weight Management is published bimonthly in print and online. It is the only publication for health care professionals that brings together authoritative applicable information, including prevention and management, patient motivation, nutrition, and strategies for implementing successful management of obese and overweight adults, children, and adolescents. Obesity and Weight Management is published in collaboration with the American Association of Diabetes Educators, American Dietetic Association, the American College of Sports Medicine, and the American Academy of Family Physicians. All published issues and tables of contents will be available free online at www.liebertpub.com/owm

Mary Ann Liebert, Inc. (www.liebertpub.com) is a privately held, fully integrated media company known for establishing authoritative medical and biomedical peer-reviewed journals, including Metabolic Syndrome and Related Disorders, Population Health Management, Diabetes Technology & Therapeutics, and Journal of Women's Health. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 60 journals, newsmagazines, and books is available at www.liebertpub.com

August 24, 2009