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UC Davis researchers visualize formation of a new synapse

(SACRAMENTO, Calif.) -- A protein called neuroligin that is implicated in some forms of autism is critical to the construction of a working synapse, locking neurons together like "molecular Velcro," a study lead by a team of UC Davis researchers has found.

Putting a name to a face may be key to brain's facial expertise

NASHVILLE, Tenn.--Our tendency to see people and faces as individuals may explain why we are such experts at recognizing them, new research indicates. This approach can be learned and applied to other objects as well.

Much touted 'depression risk gene' may not add to risk after all

Stressful life events are strongly associated with a person's risk for major depression, but a certain gene variation long thought to increase risk in conjunction with stressful life events actually may have no effect, according to researchers funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.

Study shows promise for new cancer-stopping therapy

Researchers at Nationwide Children's Hospital and Johns Hopkins University have discovered that delivering a small molecule that is highly expressed in normal tissues but lost in diseased cells can result in tumor suppression.

Antidepressant does not stop repetitive behaviors in autistic children

The antidepressant citalopram does not appear to reduce the occurrence of repetitive behaviors in children and teens with autism spectrum disorders, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Common autism medication is ineffective for repetitive behaviors, study finds

Citalopram (Celexa), a medication commonly prescribed to children with autism spectrum disorders (ASD), was no more effective than a placebo at reducing repetitive behaviors, according to a multi-site clinical trial guided by lead author Bryan H.

Citalopram no better than placebo treatment for children with autism spectrum disorders

Citalopram, a medication commonly prescribed to children with autism spectrum disorders (ASD), was no more effective than a placebo at reducing repetitive behaviors, according to researchers funded by the National Institute of Mental Health (NIMH) and other NIH institutes. The study was published in the June 2009 issue of Archives of General Psychiatry.

Antidepressant ineffective against autism spectrum disorder children's obsessive behavior

MANHASSET, NY -- A new multi-center study, conducted at The Feinstein Institute for Medical Research in collaboration with five other centers throughout the country, tested the commonly prescribed antidepressant citalopram and found that it was no more effective than placebo in altering obsessive features of the condition -- the spinning, rocking and repetitive behavior.

In rare disease, a familiar protein disrupts gene function

An international team of scientists studying a rare genetic disease discovered that a bundle of proteins with the long-established function of keeping chromosomes together also plays an important role in regulating genes in humans.

New gene linked to autism risk, especially in boys

UCLA scientists have discovered a variant of a gene called CACNA1G that may increase a child's risk of developing autism, particularly in boys. The journal Molecular Psychiatry publishes the findings in its May 19 advance online edition.

Autism in the UK costs more than $41 billion every year, shows new research

Los Angeles, London, New Delhi, Singapore and Washinton DC (18 May 2009) ? Research published this week in the Journal Autism, published by SAGE, estimate the annual costs of autism spectrum disorder (ASD) to be more than £27 billion a year. The costs of supporting children with ASDs were estimated to be £2.7 billion per year, £25 billion each year for adults.

Preclinical work shows how one gene causes severe mental retardation

Durham, N.C., and Chapel Hill, N.C. -- Researchers at Duke University Medical Center and the University of North Carolina have discovered in mice how a single disrupted gene can cause a form of severe mental retardation known as Angelman syndrome.

UNC-Duke study: Impaired brain plasticity linked to Angelman syndrome learning deficits

CHAPEL HILL -- How might disruption of a single gene in the brain cause the severe cognitive deficits associated with Angelman syndrome, a neurogenetic disorder? Researchers at the University of North Carolina at Chapel Hill School of Medicine and Duke University now believe they have the answer: impaired brain plasticity.

First neuroimaging study examining motor execution in children with autism reveals new insights

(Baltimore, MD) -- In the first neuroimaging study to examine motor execution in children with autism, researchers at the Kennedy Krieger Institute have uncovered important new insight into the neurological basis of autism.

World's largest DNA scan for autism uncovers new gene variant for disorder

UCLA scientists, in partnership with 30 research institutions across the country, have identified a new gene variant that is highly common in autistic children. And when researchers scrutinized the activity of the gene, known as CDH10, in the fetal brain, they discovered that it is most active in key regions that support language, speech and interpreting social behavior.



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