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Natural compounds, chemotherapeutic drugs may become partners in cancer therapy

CORVALLIS, Ore. -- Research in the Linus Pauling Institute at Oregon State University suggests that some natural food compounds, which previously have been studied for their ability to prevent cancer, may be able to play a more significant role in treating it -- working side-by-side with the conventional drugs that are now used in chemotherapy.

The nutritional value of Andalusian lupines is revealed

A group of researchers from the Fat Institute (CSIC) and the University of Seville have confirmed that some wild plants have a high nutritional value. The scientists have found that several species of lupins from the mountains of Andalusia have a protein content similar to that of other cultivated legumes, as they publish in the online version of the Food Chemistry magazine.

'Hedgehog' pathway may hold key to anti-cancer therapy

Scientists in Switzerland have discovered a way to block the growth of human colon cancer cells, preventing the disease from reaching advanced stages and the development of liver metastases.

How diarrheal bacteria cause some colon cancers revealed in mouse studies

Johns Hopkins scientists say they have figured out how bacteria that cause diarrhea may also be the culprit in some colon cancers. The investigators say that strains of the common Bacteroides fragilis (ETBF) dupe immune system cells into permitting runaway colon tissue inflammation, a precursor for malignant growth.

Disparities in cancer care reflect hospital resources, U-M study finds

ANN ARBOR, Mich. -- Hospitals that treat more black cancer patients have worse survival rates on average for patients with breast and colon cancer, regardless of race, according to a new study from the University of Michigan Comprehensive Cancer Center.

Research points to new target for stopping colon cancer

New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a molecule found on the surface of cells.

Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer

CLEVELAND -- A study published in this week's online issue of Nature Biotechnology, demonstrates a unique and highly sensitive method for detecting methylation-associated cancers.

Discovery may lead to powerful new therapy for asthma

GALVESTON, Texas -- University of Texas Medical Branch at Galveston researchers have found that a single enzyme is apparently critical to most allergen-provoked asthma attacks -- and that activity of the enzyme, known as aldose reductase, can be significantly reduced by compounds that have already undergone clinical trials as treatments for complications of diabetes.

Postdiagnosis aspirin use reduces risk of dying from colorectal cancer

Regular use of aspirin after colorectal cancer diagnosis may reduce the risk of cancer death, report investigators from Massachusetts General Hospital (MGH), Dana-Farber Cancer Institute and Brigham and Women's Hospital.

Colon cancer may yield to cellular sugar starvation

Scientists at the Johns Hopkins Kimmel Cancer Center have discovered how two cancer-promoting genes enhance a tumor's capacity to grow and survive under conditions where normal cells die. The knowledge, they say, may offer new treatments that starve cancer cells of a key nutrient - sugar.

Protein complex key in avoiding DNA repair mistakes, cancer

ANN ARBOR, Mich. -- As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.

Pitt researchers find promising candidate protein for cancer prevention vaccines

PITTSBURGH, Aug. 4 -- Researchers at the University of Pittsburgh School of Medicine have learned that some healthy people naturally developed an immune response against a protein that is made in excess levels in many cancers, including breast, lung, and head and neck cancers. The finding suggests that a vaccine against the protein might prevent malignancies in high-risk individuals.

A 'super sensor' for cancer and CSIs

Like the sensitive seismographs that can pick up tremors of impending earthquakes long before they strike, a similar invention from Tel Aviv University researchers may change the face of molecular biology.

Cancer's distinctive pattern of gene expression could aid early screening and prevention

AUGUSTA, Ga. -- Distinctive patterns of genes turned off -- or left on -- in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say.

New research finds possible genetic link to cause of pregnancy loss and disorders

KNOXVILLE -- Scientists at the University of Tennessee, Knoxville, and Lawrence Berkeley National Laboratory (LBNL) have published new findings about a cause of a condition at the root of genetic disorders such as Down Syndrome, pregnancy loss and infertility.



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