colon cancer
Two-thirds of the difference between death rates among African Americans and Caucasians are now due to causes that could be prevented or cured, according to a new study appearing in the Journal of Epidemiology and Community Health.
CT colonography allows radiologists to predict, with a high degree of confidence, whether or not a polyp needs to be evaluated through colonoscopy or removed through polypectomy, according to a study performed at the University of Wisconsin School of Medicine and Public Health in Madison, WI.
DENVER -- In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal canc
DENVER ? Cancer that spreads to other organs finds a particularly inviting hideout in the brain, where these metastases are usually far harder to treat than they are in other locations. Two researchers from The University of Texas M. D.
BIRMINGHAM, Ala. - A new study reveals the first-ever genetic link to the reason African-Americans are at increased risk of dying from colon cancer.
A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report.
PITTSBURGH, March 19 - Researchers at the University of Pittsburgh School of Medicine have begun testing a vaccine that might be able to prevent colon cancer in people at high risk for developing the disease.
A team of scientists at the Scripps Research Institute has found a way to use specially programmed chemicals to elicit an immediate immune response in laboratory animals against two types of cancer.
Strong-flavored onions can be harsh on your social life, but they're potentially great for fighting cancer. Researchers at Cornell University have found, in preliminary lab studies, that members of the onion family with the strongest flavor -- particularly New York Bold, Western Yellow and shallots -- are the best varieties for inhibiting the growth of liver and colon cancer cells.
Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene have been found to cause 85 percent of colon cancers. Now researchers know why. In a new paper, they explain that APC controls the conversion of dietary vitamin A into retinoic acid. If this process is impaired, colon cancer can result. ''For a long time, scientists believed they knew what the APC gene did -- that it regulated cell growth and division -- but now we know we've been missing a big piece of the picture. What we didn't know was that it converts vitamin A into retinoic acid, which is vital for normal colon cell development.''
An international research team has identified a virulent, new genetic risk factor for colon cancer ? a discovery that could lead to early screening and treatment for people who have this genetic disposition to contract the disease. The team discovered a novel mutant gene in Israeli colon cancer patients. The researchers also discovered that the presence of the gene significantly increased the risk of colon cancer among these patients.
Scientists have identified a switched-off family of genes that may prove to be a significant and early dent in a colon cell's anti-cancer armor. The inactivated genes, called SFRPs - for secreted frizzled-related protein - put the brake on a pathway of cell-growth genes that is an early step en route to cancer. Because the way SFRP genes are altered-through the attachment of so-called methyl groups-is reversible, the findings also suggest potential anti-cancer value in green tea and other compounds that affect methylation.
Investigatorshave identified a type of DNA damage caused by chronic inflammation as a potential risk factor for colorectal cancer. The findings, published this week in the early online edition of the website of the Proceedings of the National Academy of Science, shed more light on the role that inflammation might play in cancer and suggests that measurement of this type of DNA damage might be useful in assessment and management of a patient?s colorectal cancer risk.
Drinking coffee may help prevent colon cancer, according to a group of researchers in Germany. They identified a potent antioxidant compound in the popular brew that appears in animal studies to boost the activity of phase II enzymes, which are thought to protect against colon cancer, the second leading cause of cancer death in the United States.
Building on earlier studies that have shown that common painkillers known as NSAIDs (non-steroidal anti-inflammatory drugs) can reduce the risk of colon cancer in healthy people, researchers at Dana-Farber Cancer Institute have identified a mechanism by which NSAIDs inhibit the development of colon cancer. Compared with normal cells, colorectal cancer cells have abnormally high levels of an immune system protein, IL-6. David Frank, MD, PhD, and his Dana-Farber colleagues have discovered that IL-6 triggers malignant growth by activating a protein called STAT1, which transmits signals that prevent the normal scheduled death of cells in the colon.
