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Alcohol tolerance 'switch' found

October 21, 2009

Researchers at North Carolina State University have found a genetic "switch" in fruit flies that plays an important role in making flies more tolerant to alcohol.

Scientists develop novel method to generate functional hepatocytes for drug testing

October 20, 2009

Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell (iPSC) technology.

The study, led by the University of Edinburgh's MRC Centre for Regenerative Medicine, paves the way for the creation of a stem cell library that can be used for in vitro hepatic disease models.

New data showed type 2 diabetes patients experienced greater blood sugar reductions

October 15, 2009

DEERFIELD, Ill., October 14, 2009 -- A study, published online in the journal Current Medical Research and Opinion, showed that a greater percentage of patients with type 2 diabetes treated with the fixed-dose combination ACTOplus met® (pioglitazone HCl and metformin HCl) as initial therapy reached the study goal of hemoglobin A1c (HbA1c) of ≤7 percent compared to either component alone.

UCSD researchers pave the way for effective liver treatments

October 9, 2009

A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease.

In this work, the researchers have utilized an array system that can identify the biological components that can lead to or alleviate liver disease.

Liver cells grown from patients' skin cells

October 8, 2009

Scientists at The Medical College of Wisconsin in Milwaukee have successfully produced liver cells from patients' skin cells opening the possibility of treating a wide range of diseases that affect liver function. The study was led by Stephen A. Duncan, D.

Governor recognizes stem cell research at Einstein

October 8, 2009

October 8, 2009 -- (BRONX, NY) -- Albert Einstein College of Medicine of Yeshiva University hosted a roundtable discussion on stem cell research with New York Governor David A. Paterson today. Allen M. Spiegel, M.D., the Marilyn and Stanley M.

Metabolic syndrome linked to liver disease in obese teenaged boys

September 29, 2009

Researchers studying a large sample of adolescent American boys have found an association between metabolic syndrome, which is a complication of obesity, and elevated liver enzymes that mark potentially serious liver disease.

Polymorphisms of the interleukin-1 gene complex may influence alcohol dependence

September 18, 2009

Cytokines are small proteins secreted by cells that serve as molecular messengers between cells. Pro-inflammatory cytokines -- which function in the immune system -- may be involved in alcohol dependence (AD).

Penn State College of Medicine research isolates liver cancer stem cells prior to tumor formation

September 17, 2009

HERSHEY, PA -- Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer. Using a unique approach that involves study of individual cells, the team, led by C.

Genetic hint for ridding the body of hepatitis C

September 16, 2009

More than seventy percent of people who contract Hepatitis C will live with the virus that causes it for the rest of their lives and some will develop serious liver disease including cancer. However, 30 to 40 percent of those infected somehow defeat the infection and get rid of the virus with no treatment.

HBV genotype B/B3 and C/C1 are the major genotypes in Indonesia?

September 16, 2009

Previous studies revealed that HBV genotypes as well as mutations in the core promoter, precore or HBx gene have been shown to have an association with the clinical outcome of liver disease, however, this is still controversial. It is likely that this depends on the HBV genotype distribution in certain region.

Second-hand smoking results in liver disease, study finds

September 10, 2009

RIVERSIDE, Calif. -- A team of scientists at the University of California, Riverside has found that even second-hand tobacco smoke exposure can result in nonalcoholic fatty liver disease (NAFLD), a common disease and rising cause of chronic liver injury in which fat accumulates in the liver of people who drink little or no alcohol.

Gene variant heightens risk of severe liver disease in cystic fibrosis

September 8, 2009

CHAPEL HILL, N.C. -- Researchers at the University of North Carolina at Chapel Hill have discovered a genetic risk factor for severe liver disease in people with cystic fibrosis.

Women, blacks, Medicare recipients less likely to be evaluated for liver transplantation

August 31, 2009

PITTSBURGH, Aug. 31 -- Patient race, gender and insurance status influence decisions about who will go on to receive liver transplants, according to a University of Pittsburgh School of Medicine study.

Researchers find high-dose therapy for liver disease not effective

August 28, 2009

ROCHESTER, Minn. -- A national team of researchers led by scientists at Mayo Clinic has found that a common treatment for primary sclerosing cholangitis, a chronic liver disease, is not helpful for patients, according to a study published this month in the journal Hepatology.



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