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Researchers find high-dose therapy for liver disease not effective

ROCHESTER, Minn. -- A national team of researchers led by scientists at Mayo Clinic has found that a common treatment for primary sclerosing cholangitis, a chronic liver disease, is not helpful for patients, according to a study published this month in the journal Hepatology.

Racial disparity studied in patients undergoing liver transplantation for hepatitis B

According to the Centers for Disease Control and Prevention (CDC) 1.5 to 2 million Americans are infected with the hepatitis B virus (HBV). Prior studies have shown there to be significant racial differences in access to and outcomes of liver transplantation. Recently, doctors from across the U.S.

Study finds adverse effects in treatment for primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is an uncommon chronic liver disease characterized by progressive inflammation and destruction of the bile ducts. The disease progresses slowly, usually leading to biliary cirrhosis, portal hypertension and liver failure over a 10-15 year period.

Spot urine test: To monitor dietary sodium compliance in liver disease patients?

A research article to be published on August 7 , 2009 in the World Journal of Gastroenterology addresses this question. Study designed by Dr. El-Bokl and performed by Dr. Senousy and colleagues evaluated using spot urine Na/K ratio as an alternative. Forty patients with liver cirrhosis and ascites were admitted to Ain Shams University Hospital in Cairo, Egypt.

Gallbladder emptying in primary sclerosing cholangitis patients

Primary sclerosing cholangitis (PSC) is an idiopathic chronic cholestatic inflammatory liver disease characterized by diffuse fibrosing inflammation of intra- and/or extrahepatic bile ducts, resulting in bile duct obliteration, biliary cirrhosis, and eventually hepatic failure.

Extreme BMI cause for concern in liver transplantation

A recent study by doctors at the University of Washington explained that patients who are significantly underweight or very severely obese prior to liver transplantation are at increased risk of death following transplantation surgery.

Studies reveal hepatitis C virus carriers experience substantial increase in mortality

Hepatitis C virus (HCV) is a blood-borne disease that causes inflammation of the liver and to which there is currently no vaccine available.

Discovery to aid in future treatments of third-world parasites

Saranac Lake, NY - Schistosomiasis, one of the most important of the neglected tropical diseases, is caused by infection with parasitic helminths of the genus Schistosoma. These parasites are long lived (>10 years) and dwell within blood vessels, where they produce eggs that become the focus of intense, chronic inflammatory responses.

Hepatitis C: No overall difference in sustained viral response in most widely used treatments

DURHAM, N.C. -- Findings from the largest study to date comparing the efficacy of competing treatments for chronic hepatitis C infection (HCV) show that the regimens are similar when it comes to safety and their ability to provoke long-term viral eradication, according to researchers at Duke University Medical Center.

Hepatitis C infection: treatment options equally effective, likelihood of success known early on

Results of a long-awaited study of 3,070 American adults at Johns Hopkins and 118 other U.S. medical centers show that treatment with either of the two standard antiviral drug therapies is safe and offers the best way for people infected with hepatitis C to prevent liver scarring, organ failure and death.

Scientists link immune system's natural killer cells to infant liver disease

CINCINNATI -- Scientists have linked an overactive response by one of the immune system's key weapons against infection -- natural killer, or NK, cells -- to the onset of biliary atresia in infants, a disease where blocked bile ducts can cause severe liver damage and death.

Secrets of a life-giving amino acid revealed by Yale researchers

Selenium is a trace element crucial to life - too little or too much of it is fatal. In the July 17 issue of the journal Science, researchers at Yale University and University of Illinois at Chicago detail the molecular mechanisms that govern its metabolism in the human body.

Young offenders' health critical to rehabilitation

The physical and mental health needs of juvenile offenders should be treated as a priority if offenders held in detention have any real hope of rehabilitation, according to new research from the University of Adelaide, Australia.

Young offenders' health critical to rehabilitation

The physical and mental health needs of juvenile offenders should be treated as a priority if offenders held in detention have any real hope of rehabilitation, according to new research from the University of Adelaide, Australia.

Good news for some hard-to-treat hepatitis C patients

ST. LOUIS -- In a multi-center trial led by a Saint Louis University researcher, investigators found that a new combination therapy of daily consensus interferon and ribavirin helps some hepatitis C patients who have not responded to previous treatment.



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