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Novel mouse gene reduces major pathologies associated with Alzheimer's disease

A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD).

Widely used cholesterol-lowering drug may prevent progression

(CHICAGO) ?Simvastatin, a commonly used, cholesterol-lowering drug, may prevent Parkinson's disease from progressing further.

Member of NFL Hall of Fame diagnosed with degenerative brain disease

(BOSTON) -- The Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) announced today that a recently deceased member of the NFL Hall of Fame suffe

Researchers identify gene variant linked to glaucoma

An international team, led by researchers from the University of California, San Diego School of Medicine and the National Eye Institute, has discovered gene variants for glaucoma in a black population. The finding could lead to future treatments or a cure for this disease, which leads to blindness in two million Americans each year.

MassGeneral Hospital for Children study explains some mysteries of neonatal seizures

A study led by MassGeneral Hospital for Children (MGHfC) investigators is providing new insight into the mechanism of neonatal seizures, which have features very different from seizures in older children and adults. In their report in the Sept.

Transplanted human stem cells prolong survival in mouse model of rare brain disease

A new study finds substantial improvement in a mouse model of a rare, hereditary neurodegenerative disease after transplantation of normal human neural stem cells.

Watching stem cells repair the human brain

There is no known cure for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's. But new hope, in the form of stem cells created from the patient's own bone marrow, can be found ― and literally seen ― in laboratories at Tel Aviv University.

Mighty mice: Treatment targeted to muscle improves motor neuron disease

New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement.

Brain Tips for the Summer Months

July 28, 2009 by mcole

The summer months provide a great opportunity to review the health of your brain and to get started following some of the simple steps articulated in Dr. Nussbaum’s Brain Health Lifestyle. You will soon be on your way to building brain reserve, promoting your own brain health, and enhancing your brain’s ability to delay the onset of neurodegenerative disease.

1. Get Moving!

Scientists shed new light on cause of inherited movement disorder

SALT LAKE CITY -- University of Utah School of Medicine researchers and their colleagues at University of Texas (UT) Southwestern Medical Center have found strong evidence that abnormal calcium signaling in neurons may play an important role in the development of spinocerebellar ataxia type 2 (SCA2), a disorder causing progressive loss of coordination, speech difficulty, and abnormal eye movem

Huntington's disease deciphered

Researchers at the University of Illinois at Chicago College of Medicine have discovered how the mutated huntingtin gene acts on the nervous system to create the devastation of Huntington's disease. The report of their findings is available in Nature Neuroscience online.

What separates dangerous blood vessel plaques from benign ones

Researchers say they have evidence to explain what separates your average blood vessel plaque from those that are at high risk for triggering the development of dangerous--even fatal--blood clots.

Combination of genetic and environmental 'hits' required for Parkinson's disease

New research finds that a complex interaction between separate factors underlies the pathology associated with Parkinson's disease (PD), reinforcing the concept that multiple therapeutic targets should be considered when designing treatment strategies.

Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time

Extensive death of nerve cells leads to severe dementia in patients with Alzheimer's disease. Until now, it has only been possible to investigate the neuronal devastation in post mortem animal models, and by using complicated methods.

Scripps scientists uncover mimicry at the molecular level that protects genome integrity

The new study, which was published on April 12, 2009, in an advanced online edition of the journal Nature Structural & Molecular Biology, draws new parallels between the Rad60 DNA repair factor and SUMO, a small ubiquitin-like modifier, which are both essential for maintaining genome stability during replication.



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