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UT Southwestern researchers examine mechanisms that help cancer cells proliferate

DALLAS -- Sept. 1, 2009 -- A process that limits the number of times a cell divides works much differently than had been thought, opening the door to potential new anticancer therapies, researchers at UT Southwestern Medical Center report in the Aug. 7 issue of the journal Cell.

Stanford discovery pinpoints new connection between cancer cells, stem cells

STANFORD, Calif. -- A molecule called telomerase, best known for enabling unlimited cell division of stem cells and cancer cells, has a surprising additional role in the expression of genes in an important stem cell regulatory pathway, say researchers at the Stanford University School of Medicine.

New insight into how tumors evade the immune system

A new research study sheds light on how cancer cells manage to evade the immune system despite the presence of tumor-specific immune cells. The researchers found that mouse and human melanoma cells secrete galectin-1, which has a negative impact on the survival of T cells, and that inhibition of Gal-1 dramatically reduces tumor formation in mice. The research has exciting implications for future anticancer therapies that may stimulate an effective immune response against tumor cells.



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