Active immunisation can stimulate the body to produce highly efficient IgE antibodies that attack tumours. This breakthrough, achieved in an animal model, is based on the skilful combination of two established experimental methods. The results are now being published in Cancer Research and are part of a project funded by the Austrian Science Fund FWF. The antibodies produced during the project belong to a class that also plays a key role in the development of allergic reactions. Consequently, the results will be a key focal point at the 1st International AllergoOncology Symposium, which is to be held today in Vienna, Austria.

VIENNA, Austria and CHAPEL HILL, N.C., US, March 7 -- AOP Orphan Pharmaceuticals AG ("AOP Orphan") and Lantibio, Inc. ("Lantibio") today announced positive final results from their placebo controlled, double-blinded Phase II clinical study of Moli1901, an experimental compound to treat cystic fibrosis ("CF"). Moli1901 is being developed by AOP Orphan in Europe under a licensing and commercialization agreement with Lantibio. The study, performed at multiple centers in Europe, was designed to investigate safety and tolerability of aerosolized Moli1901 in adolescents (12 years of age or older) and adults with CF.

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