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New maize map to aid plant breeding efforts

November 19, 2009

In a massive survey of genetic diversity in maize, also known as corn, researchers across the United States, have developed a gene map that should pave the way to significant improvements in a plant that is a major source of food, fuel, animal feed and fiber around the world.

Reference genome of maize, most important US crop, is published by team co-led by CSHL scientists

November 19, 2009

Cold Spring Harbor, NY -- A four-year, multi-institutional effort co-led by three Cold Spring Harbor Laboratory (CSHL) scientists culminated today in publication of a landmark series of papers in the journal Science revealing in unprecedented detail the DNA sequence of maize (Zea mays).

Largest gene study of childhood IBD identifies 5 new genes

November 15, 2009

In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease.

Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor

November 11, 2009

CAMBRIDGE, MA -- November 11, 2009 -- Aileron Therapeutics, a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides, announced today that its collabora

UCSD discovery allows scientists for the first time to experimentally annotate genomes

November 9, 2009

Over the last 20 years, the sequencing of the human genome, along with related organisms, has represented one of the largest scientific endeavors in the history of mankind.

Study sheds light on evolution of human complexity

November 3, 2009

A painstaking analysis of thousands of genes and the proteins they encode shows that human beings are biologically complex, at least in part, because of the way humans evolved to cope with redundancie

'Moonlighting' molecules discovered

October 29, 2009

Since the completion of the human genome sequence, a question has baffled researchers studying gene control: How is it that humans, being far more complex than the lowly yeast, do not proportionall

Hunting for the Prozac gene

October 27, 2009

Prozac works wonders for some depressed people, but not for others. In some cases, patients derive little benefit and at worst, it can lead to bizarre hallucinations and fits of rage.

TraDIS technique tackles typhoid

October 16, 2009

For the first time, researchers are able to look at the need for every gene in a bacterial cell in a single experiment. The new method will transform the study of gene activity and the search for weaknesses in bacterial armouries.

What drives our genes? Salk researchers map the first complete human epigenome

October 14, 2009

LA JOLLA, CA -- Although the human genome sequence faithfully lists (almost) every single DNA base of the roughly 3 billion bases that make up a human genome, it doesn't tell biologists much about how its function is regulated.

Scientists use math modeling to predict unknown biological mechanism of regulation

October 14, 2009

AUSTIN, Texas -- A team of scientists, led by a biomedical engineer at The University of Texas at Austin, have demonstrated -- for the first time -- that mathematical models created from data obtained by DNA microarrays, can be used to correctly predict previously unknown cellular mechanisms.

UCR researchers develop genetic map for cowpea, accelerating development of new varieties

October 13, 2009

RIVERSIDE, Calif. -- Cowpea, a protein-rich legume crop, is immensely important in many parts of the world, particularly drought-prone regions of Africa and Asia, where it plays a central role in the diet and economy of hundreds of millions of people.

Gene data tool advances prospects for personalized medicine

October 8, 2009

A sophisticated computational algorithm, applied to a large set of gene markers, has achieved greater accuracy than conventional methods in assessing individual risk for type 1 diabetes.

Scientists decipher the 3-D structure of the human genome

October 8, 2009

CAMBRIDGE, Mass. -- Scientists have deciphered the three-dimensional structure of the human genome, paving the way for new insights into genomic function and expanding our understanding of how cellular DNA folds at scales that dwarf the double helix.

Establishing standard definitions for genome sequences

October 8, 2009

In 1996, researchers from major genome sequencing centers around the world convened on the island of Bermuda and defined a finished genome as a gapless sequence with a nucleotide error rate of one or less in 10,000 bases. This effectively set the quality target for the human genome effort and was quickly applied to other genome projects.



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