Decaf coffee preserves memory function
Researchers from Mount Sinai School of Medicine have discovered that decaffeinated coffee may improve brain energy metabolism associated with type [...]
Tag Archives: Alzheimer 
Protein changes identified in early-onset Alzheimer’s
With a lack of effective treatments for Alzheimer’s, most of us would think long and hard about whether we wanted [...]
Alzheimer’s drug candidate may be first to prevent disease progression
A new drug candidate may be the first capable of halting the devastating mental decline of Alzheimer’s disease, based on [...]
Antioxidant has potential in the Alzheimer’s fight
When you cut an apple and leave it out, it turns brown. Squeeze the apple with lemon juice, an antioxidant, and the process slows down. Simply put, that same “browning” process — known as oxidative stress — happens in the brain as A…
Biochemical signature predicts progression to Alzheimer’s disease
A study led by Research Professor Matej Oreič from VTT Technical Research Centre of Finland suggests that Alzheimer’s disease is preceded by a molecular signature indicative of hypoxia and up-regulated pentose phosphate pathway. This indicator c…
Researchers create Alzheimer’s antibodies
Troy, N.Y. — Researchers at Rensselaer Polytechnic Institute have developed a new method to design antibodies aimed at combating disease. The surprisingly simple process was used to make antibodies that neutralize the harmful protein particles that …
Drug reverses aging-associated changes in brain cells
Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study in the December 7 issue of The Journal of Neuroscience. T…
A natural dye obtained from lichens may combat Alzheimer’s disease
A red dye derived from lichens that has been used for centuries to color fabrics and food appears to reduce the abundance of small toxic protein aggregates in Alzheimer’s disease. The dye, a compound called orcein, and a related substance, called O4, b…
Diametric shift in 2 protein levels spurs Alzheimer’s plaque accumulation
AUGUSTA, Ga. — A diametric shift in the levels of two proteins involved in folding, moving and cutting other proteins enables accumulation of the destructive brain plaque found in Alzheimer’s disease, researchers report.
VPS35 is a protein that fold…
Eating fish reduces risk of Alzheimer’s disease
People who eat baked or broiled fish on a weekly basis may be improving their brain health and reducing their [...]
Human stem cells transformed into key neurons lost in Alzheimer’s
CHICAGO — Northwestern Medicine researchers for the first time have transformed a human embryonic stem cell into a critical type of neuron that dies early in Alzheimer’s disease and is a major cause of memory loss.
This new ability to reprogram …
Scripps Research study points to liver, not brain, as origin of Alzheimer’s plaques
LA JOLLA, CA — March 3, 2011 — Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists’ ideas about Alzheimer’s disease — pointing to the liver instead of the brain as the source of the “am…
Silk moth’s antenna inspires new nanotech tool with applications in Alzheimer’s research
ANN ARBOR, Mich.—By mimicking the structure of the silk moth’s antenna, University of Michigan researchers led the development of a better nanopore—a tiny tunnel-shaped tool that could advance understanding of a class of neurodegenerative di…
An Alzheimer’s vaccine in a nasal spray
One in eight Americans will fall prey to Alzheimer’s disease at some point in their life, current statistics say. Because Alzheimer’s is associated with vascular damage in the brain, many of them will succumb through a painful and potentially fatal …
How disordered proteins spread from cell to cell, potentially spreading disease
One bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that’s necessary to corrupt other proteins, forming large aggregations linked to several incurable neurodegenerative diseases such as Huntington’s, Parkinson…
Tau-induced memory loss in Alzheimer’s mice is reversible
Amyloid-beta and tau protein deposits in the brain are characteristic features of Alzheimer disease. The effect on the hippocampus, the area of the brain that plays a central role in learning and memory, is particularly severe. However, it app…
Financial planning a key but neglected component of Alzheimer’s care, say researchers
Patients newly diagnosed with Alzheimer’s disease or other dementias, and their families, need better guidance from their physicians on how to plan for the patient’s progressive loss of ability to handle finances, according to a study led by a physi…
Increasing brain enzyme may slow Alzheimer’s disease progression
LOS ANGELES — Increasing puromycin-sensitive aminopeptidase, the most abundant brain peptidase in mammals, slowed the damaging accumulation of tau proteins that are toxic to nerve cells and eventually lead to the neurofibrillary tangles, a m…
