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Researchers create powerful stem cells from blood

The particularly powerful ? and very scarce ? flexible forms of stem cells needed for medical research and treatment may now be both plentiful and simple to produce, with a new technology developed at the U.S. Department of Energy’s Argonne National Laboratory ? and the source is as close as your own bloodstream. These flexible stem cells, able to morph into a variety of cell types, are called “pluripotent,” and before this Argonne research, they have been found only in fetal tissue, which is limited, and in bone marrow, which is difficult to collect. Pluripotent stem cells are important because they can generate all types of tissues found in the body, and the Argonne-developed technology can produce them from adult blood cells.

Researchers Apply Combat Simulation Technology to Homeland Security

Using a computer code originally developed for combat simulation, researchers from the Lawrence Livermore National Laboratory are supplying the same expertise that analyzes concepts of operation, technology and training to emergency responders as a part of the Lab’s role in homeland security. The Analytical Conflict and Tactical Simulation (ACATS) is an offshoot of the Joint Conflict and Tactical Simulation (JCATS) that the military uses for training, analysis, mission planning and mission rehearsal. JCATS also has been used to support actual military operations in places such as Panama and the Persian Gulf.

Thalidomide-like drug appears to help bone cancer patients

A drug similar to thalidomide has been found to be promising with fewer side effects for treating patients with recurrent multiple myeloma, an incurable form of bone marrow cancer, according to early data from a clinical study. The drug, an analog of thalidomide, was developed to be more potent than thalidomide, while reducing some of thalidomide’s dose limiting side effects. Laboratory studies have shown that CC-5013 not only kills myeloma cells by triggering their innate self-destruct mechanism but also inhibits the myeloma cells ability to localize and grow in the bone marrow. Moreover, it appears to have anti-angiogenic effects and stimulates the immune system to attack myeloma.