Tag Archives: new england journal of medicine

U.S. hospital admission rates linked with high readmissions

High hospital readmission rates in different regions of the U.S. may have more to do with the overall high use of hospital services in those regions than with the severity of patients’ particular conditions or problems in the quality of care during and…

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Gene therapy achieves early success against hemophilia

Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children’s Research Hospital in Memphis and de…

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Research offers new pathway of multiple sclerosis

Working together, researchers at Cleveland Clinic and Mayo Clinic have for the first time examined early multiple sclerosis (MS) brain lesions in the cerebral cortex. These lesions are thought to be critical to MS progressi…

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Combination of everolimus and exemestane improves survival for women with metastatic breast cancer

San Antonio, TX – In an international Phase III randomized study, everolimus, when combined with the hormonal therapy exemestane, has been shown to dramatically improve progressionSan Antonio, TX – In an international Phase III randomized study, everol…

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Bedside ultrasound becomes a reality

Clinicians have often referred to ultrasound technology as the “stethoscope of the future,” predicting that as the equipment shrinks in size, it will one day be as common at the bedside as that trusty tool around every physician’s neck. According to…

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Study links hypoxia and inflammation in many diseases

AURORA, Colo. (Feb. 18, 2011) — When the body is deprived of oxygen during a major surgery, the kidneys, heart muscles or lungs can be injured as a result. The problem is that lack of oxygen can lead to inflammation.
Yet some athletes d…

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SMFM highlights significance of spina bifida research findings

SAN FRANCISCO (February 10, 2011) — More than two thousand physicians, some of the top obstetric/gynecologists in the world who specialize in maternal-fetal medicine, especially high risk pregnancies, gathered today for their annual meeting in Sa…

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HPV vaccine works for boys: Study shows first clear benefits

The vaccine for human papillomavirus (HPV) can prevent 90 percent of genital warts in men when offered before exposure to the four HPV strains covered by the vaccine, according to a new multi-center study led by H. Lee Moffitt Cancer Center and UCSF…

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Buprenorphine is better than methadone for opioid dependence in pregnant women, study shows

Using buprenorphine instead of methadone — the current standard of care — to treat opioid-dependent pregnant women may result in healthier babies, suggests new findings from an international team led by Johns Hopkins researchers and publish…

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Buprenorphine treatment produces improved outcome for babies born addicted

Babies born into the world addicted to drugs because of their mother’s dependence on pain medication, or opioids, may be weaned off the substance more comfortably, with a shorter hospital stay and at a reduced cost, if the mother receives a new …

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Hospital perks: How much should hospitals be rewarded for the patient experience?

From hotel-style room service to massage therapy to magnificent views, hospitals are increasingly touting their luxury services in a bid to gain market share, especially those in competitive urban markets. An important new article, published today i…

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Use of HIV medications reduces risk of HIV infection in uninfected people

(San Francisco, CA) — In a finding with the potential to fundamentally change strategies to slow the global HIV epidemic, a new study called iPrEx shows that individuals at high risk for HIV infection who took a single daily tablet containing two …

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AIDS drug shown to prevent HIV in multinational trial of HIV-negative gay men

Chicago, November 23, 2010 — Results of the world’s first efficacy trial of an HIV-prevention approach called oral pre-exposure prophylaxis, or PrEP, were released online in the New England Journal of Medicine today. Data from this trial, called i…

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Keeping blood pressure in check may benefit some African-Americans with kidney disease

DALLAS — Oct. 7, 2010 — Keeping blood pressure at a low level in African-Americans with kidney disease may slow the progression of the condition in patients with proteinuria, UT Southwestern Medical Center researchers found in a national study p…

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Low Lead Levels Linked with IQ Deficits

A new study suggests that lead may be harmful even at very low blood concentrations. The study, funded by the National Institute of Environmental Health Sciences of the National Institutes of Health, will appear in the April 17 edition of The New England Journal of Medicine. The five-year study found that children who have blood lead concentration lower than 10 micrograms per deciliter suffer intellectual impairment from the exposure.

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In calamity, hospitals can safely evacuate patients

In the event of a significant threat to their buildings and facilities, hospitals can successfully evacuate patients and staff without relying on outside assistance, a UC Irvine study found. The study, which appears in the April 3 issue of the New England Journal of Medicine, also suggests that in the aftermath of a severely damaging earthquake or similarly devastating terrorist event, the biggest risk to hospitals isn’t structural integrity, but non-structural damage like water leaks and electrical outages. The findings include basic steps for responding to a bioterrorist attack on a medical facility.

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Drug slows progression of moderate to severe Alzheimer's disease

A drug that quashes the activity of a key brain chemical is the first effective treatment for patients in the later stages of Alzheimer’s disease, according to the results of a large multi-center clinical study published in the April 3 issue of the New England Journal of Medicine. The drug, memantine, slows the mental and physical deterioration of patients with moderate to severe Alzheimer’s disease, according to Barry Reisberg, M.D., Professor of Psychiatry at NYU School of Medicine, who led the study. “These patients seem to be declining much less, about half as much as ordinarily expected, over a six-month period,” says Dr. Reisberg. “This medication will slow down the otherwise inexorable progress of this disease, and it is remarkably free of side effects. These are very impressive results. It looks like this drug really will have an impact on this disease,” he says.

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Drug cuts deaths, hospital stays in heart attack patients

A drug that blocks a heart-harming hormone can significantly reduce the risk of death and hospitalization in heart attack patients who have heart failure, with minimal side effects, a new international study released today shows. The life-saving effect began soon after patients begin taking the drug, called eplerenone, following their heart attacks. The effect was especially strong if patients were also on other heart medications, according to the results of the randomized, double-blind, placebo-controlled study of 6,632 patients in 37 countries.

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