Men who take non-steroidal anti-inflammatory drugs three times a day for more than three months are 2.4 times more likely to have erectile dysfunction compared to men who do not take those drugs regularly, according to a Kaiser Permanente study publ…
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BUFFALO, N.Y. — University at Buffalo neuroscience researchers conducting basic research on ion channels have demonstrated a process that could have a profound therapeutic impact on pain.
Targeting these ion channels pharmacologically would offer …
Tampa, FL (August 23, 2010) — A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer’s disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a …
Researchers from the Cancer Center at the University of Minnesota have found that adult women taking aspirin two or more times a week may lower their risk of adult leukemia by more than 50 percent. The study will be published in the June 13 edition of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Building on earlier studies that have shown that common painkillers known as NSAIDs (non-steroidal anti-inflammatory drugs) can reduce the risk of colon cancer in healthy people, researchers at Dana-Farber Cancer Institute have identified a mechanism by which NSAIDs inhibit the development of colon cancer. Compared with normal cells, colorectal cancer cells have abnormally high levels of an immune system protein, IL-6. David Frank, MD, PhD, and his Dana-Farber colleagues have discovered that IL-6 triggers malignant growth by activating a protein called STAT1, which transmits signals that prevent the normal scheduled death of cells in the colon.
Regular use of ibuprofen and aspirin inhibits the formation and growth of breast cancer, according to data published in the Proceedings for the 94th Annual Meeting of the American Association for Cancer Research (AACR). The data, taken from the National Cancer Institute?s (NCI) Women?s Health Initiative (WHI) Observational Study, concluded that weekly doses of non-steroidal anti-inflammatory drugs (NSAIDs) had a significant effect in reducing the risk of breast cancer.
?These results suggest that even women at high risk for breast cancer may be protected by taking NSAIDs,? explains Randall Harris, M.D., Ph.D., lead investigator of the study, professor of the division of epidemiology and biometrics at the Ohio State University. ?However, before usage guidelines for NSAIDs can be implemented, additional studies are needed.?
Researchers have found evidence that non-steroidal anti-inflammatory drugs (NSAIDs) including ibuprofen, aspirin, and naproxen, may exert a protective effect against the risk of Alzheimer’s disease. Results of their epidemiological, multiple-study analysis of nearly 16,000 patients are being presented at the American Academy of Neurology Annual Meeting in Honolulu, March 29-April 5, 2003.
In a breakthrough study, scientists have found that common painkillers such as ibuprofen and naproxen may actually dissolve the brain lesions — or amyloid plaques — that are one of the definitive hallmarks of Alzheimer’s disease. The findings are reported in the March 31 issue of Neuroscience. Principal investigator Jorge R. Barrio, professor of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA, has used FDDNP, a new chemical marker developed in his laboratory at UCLA, to visually zero in on the brain lesions present in Alzheimer’s disease. He discovered that common over-the-counter pain medications — known as non-steroidal anti-inflammatory drugs — bind to amyloid plaques, and may help dissolve existing plaques and prevent the formation of new ones.
A new study has found that consumption of moderate amounts of green or white tea might provide a protection against colon tumors about as well as a prescription drug, sulindac, that has been shown to be effective for that purpose. The research was just published in the journal Carcinogenesis by scientists from the Linus Pauling Institute at Oregon State University, in studies funded by the National Cancer Institute. It may suggest some optional approaches to cancer prevention or therapy, especially for people who have trouble with the side effects that can be associated with regular use of non-steroidal anti-inflammatory drugs, or NSAIDs, such as sulindac or aspirin.