Tag Archives: proceedings of the national academy of sciences

Microsensors offer first look at whether cell mass affects growth rate

CHAMPAIGN, Ill. — University of Illinois researchers are using a new kind of microsensor to answer one of the weightiest questions in biology — the relationship between cell mass and growth rate.
The team, led by electrical and computer engin…

Leave a comment Continue Reading →

Multiple fathers prevalent in Amazonian cultures

COLUMBIA, Mo. — In modern culture, it is not considered socially acceptable for married people to have extramarital sexual partners. However, in some Amazonian cultures, extramarital sexual affairs were common, and people believed that when a woma…

Leave a comment Continue Reading →

Growth defects in cystic fibrosis may start before birth

A new study using a pig model of cystic fibrosis (CF) suggests that low levels of a growth promoting hormone at or before birth may contribute to growth defects in patients with CF.
The study, led by University of Iowa researchers and published…

Leave a comment Continue Reading →

Cell membranes behave like cornstarch and water

Mix two parts cornstarch and one part water. Swirl your fingers in it slowly and the mixture is a smoothly flowing liquid. Punch it quickly with your fist and you meet a rubbery solid — so solid you can jump up and down on a vat of it.
It t…

Leave a comment Continue Reading →

Lactate in the brain reveals aging process

Researchers at the Swedish medical university Karolinska Institutet have shown that they may be able to monitor the aging process in the brain, by using MRI technique to measure the brain lactic acid levels. Their findings suggest that the lactate l…

Leave a comment Continue Reading →

Gene activity in the brain depends on genetic background

SEATTLE, Wash. — October 18, 2010 — Researchers at the Allen Institute for Brain Science have found that the same genes have different activity patterns in the brain in individuals with different genetic backgrounds. These findings may help to exp…

Leave a comment Continue Reading →

Second-generation device more effective in capturing circulating tumor cells

A redesigned version of the CTC-Chip — a microchip-based device for capturing rare circulating tumor cells (CTCs) — appears to be more effective and should be easier to manufacture than the original. Called the HB-(herringbone) Chip, the ne…

Leave a comment Continue Reading →

Gambling on bacteria

When it comes to gambling, many people rely on game theory, a branch of applied mathematics that attempts to measure the choices of others to inform their own decisions. It’s used in economics, politics, medicine — and, of course, Las Vegas. But re…

Leave a comment Continue Reading →

Hebrew University research holds promise for development of new osteoporosis drug

Jerusalem, October 4, 2010 — Researchers at the Hebrew University of Jerusalem have discovered a group of substances in the body that play a key role in controlling bone density, and on this basis they have begun development of a drug for prev…

Leave a comment Continue Reading →

Feasts at a funeral

Whether the occasion is a wedding reception or another milestone in life, the feast is a time-honored ritual in which a large meal marks a significant occasion. We know that the Romans, Greeks and Vikings did it, and today it’s still an active…

Leave a comment Continue Reading →

U of M research provides insights into the roots of gamblers’ fallacies and other superstitions

Gamblers who think they have a “hot hand,” only to end up walking away with a loss, may nonetheless be making “rational” decisions, according to new research from University of Minnesota psychologists. The study finds that because humans are making …

Leave a comment Continue Reading →

New study shows that oilsands mining and processing are polluting the Athabasca River

Edmonton — Inorganic elements known to be toxic at low concentrations are being discharged to air and water by oilsands mining and processing according to University of Alberta (U of A) research findings being published this month in one of the wor…

Leave a comment Continue Reading →

Researchers find gene responsible for neurodegenerative disease in dogs, possibly in humans

A North Carolina State University researcher has helped to locate and identify a gene responsible for a fatal neurodegenerative disease that affects American Staffordshire terriers. This same gene may be responsible for a similar rare, fatal disease…

1 Comment Continue Reading →

Human genome rife with 400 ‘fragile zones’

Researchers have uncovered evidence that major evolutionary changes are more likely to occur in approximately 400 ‘fragile’ genomic regions that account for only 5 percent of the human genome. The findings, reported in the June 24 issue of the Proceedings of the National Academy of Sciences (PNAS), undercut the widely held view among scientists that evolutionary breakpoints ? disruptions in the order of genes on chromosomes ? are purely random. Apart from its implications for evolutionary theory, the study could have major implications for medical research related to diseases such as leukemia, which are caused by clinical (rather than evolutionary) chromosomal breakpoints.

Leave a comment Continue Reading →

Wrinkle-free mice provide clues about obesity, wrinkles and hair growth

What do wrinkles, hair growth and obesity have in common? All three may involve the same gene, according to researchers at Washington University School of Medicine in St. Louis. The team discovered that mice with a mutation in the gene that produces a protein already being investigated as a target for anti-obesity drugs fail to develop wrinkles or normal hair growth.

Leave a comment Continue Reading →

Redheaded women respond better to painkilling drug

A gene associated with red hair and fair skin may also be responsible for how females respond to painkillers, according to a study conducted by lead researcher Jeffrey Mogil, a McGill University psychology professor, and collaborators in the United States. Results of their study are to be released today in Proceedings of the National Academy of Sciences of the USA (article #03-0053). “While we believe pain is the same in all women of all hair colours,” explained Mogil, “our study shows women with red hair respond better to the pain-killing drug we tested than anyone else — including men.”

Leave a comment Continue Reading →

Common Acne Treatment Stops Blindness in Animal Model

Administering Accutane, a drug commonly used to treat acne, UCLA researchers have successfully stopped the accumulation of toxic pigments in the eyes of animals with a genetic defect similar to Stargardt’s macular degeneration. The UCLA team gave a daily injection of Accutane to mimic the effect of constant light deprivation and the results proved dramatic. These toxic pigments, called lipofuscin, are responsible for the visual loss in patients with Stargardt’s disease.

Leave a comment Continue Reading →

Researchers find human body produces ozone

In what is a first for biology, a team of investigators is reporting that the human body makes ozone. The team has been slowly gathering evidence over the last few years that the human body produces the reactive gas — most famous as the ultraviolet ray-absorbing component of the ozone layer — as part of a mechanism to protect it from bacteria and fungi. “Ozone was a big surprise,” says researcher Bernard Babior. “But it seems that biological systems manufacture ozone, and that ozone has an effect on those biological systems.”

Leave a comment Continue Reading →