New research by scientists at The Scripps Research Institute has underlined the power of an endogenous anti-stress peptide in the brain to prevent and even reverse some of the cellular effects of acute alcohol and [...]
Tag Archives | scripps research institute
Study Shows Potential of Anti-Stress Peptide to Block Alcohol Dependence
Schizophrenics too wound up, literally
Scientists at The Scripps Research Institute have discovered that DNA stays too tightly wound in certain brain cells of schizophrenic subjects. The findings suggest that drugs already in development for other diseases might eventually offer [...]
Alzheimer’s drug candidate may be first to prevent disease progression
A new drug candidate may be the first capable of halting the devastating mental decline of Alzheimer’s disease, based on the findings of a study published in PLoS ONE. When given to mice with Alzheimer’s, [...]
Potential of anti-stress peptide to block alcohol dependence
New research by scientists at the Scripps Research Institute has underlined the power of an endogenous anti-stress peptide in the brain to prevent and even reverse some of the cellular effects of acute alcohol and alcohol dependence in …
Scripps Research scientists create cell assembly line
JUPITER, FL, March 3, 2011 — Borrowing a page from modern manufacturing, scientists from the Florida campus of The Scripps Research Institute have built a microscopic assembly line that mass produces synthetic cell-like compartments.
The new com…
Scripps Research study points to liver, not brain, as origin of Alzheimer’s plaques
LA JOLLA, CA — March 3, 2011 — Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists’ ideas about Alzheimer’s disease — pointing to the liver instead of the brain as the source of the “am…
Scripps Research study sheds light on RNA ‘on/off switches’
LA JOLLA, CA — Embargoed by the journal Nature Structural and Molecular Biology until February 13, 2011, 1 PM Eastern time — Scientists from The Scripps Research Institute have shed new light on a molecular switch that turns genes on or off in r…
Scripps Research compound blocks brain cell destruction in Parkinson’s disease
JUPITER, FL, February 11, 2011 — Scientists from the Florida campus of The Scripps Research Institute have produced the first known compound to show significant effectiveness in protecting brain cells directly affected by Parkinson’s disease, a pr…
Scientists develop method to identify fleetingly ordered protein structures
LA JOLLA, CA — February 8, 2011 – A team of scientists from The Scripps Research Institute and the University of California, San Diego (UCSD) have developed a novel technique to observe previously unknown details of how folded structures are forme…
Scripps Research scientists convert skin cells to beating heart cells
LA JOLLA, CA — Scripps Research Institute scientists have converted adult skin cells directly into beating heart cells efficiently without having to first go through the laborious process of generating embryonic-like stem cells. The powerful gener…
Scripps Research scientists reveal key mechanism governing nicotine addiction
JUPITER, FL — January 25, 2011 — Embargoed by the journal Nature until January 30, 1 PM Eastern time — Scientists from the Florida campus of The Scripps Research Institute have identified a pathway in the brain that regulates an individual’s v…
Scientists reveal complete structure of HIV’s outer shell
LA JOLLA, CA — A team of scientists at The Scripps Research Institute and the University of Virginia has determined the structure of the protein package that delivers the genetic material of the human immunodeficiency virus (HIV) to human cells.
…
Scripps Research team creates new synthetic compound with HIV-fighting promise
LA JOLLA, CA — January 18, 2011 — Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to te…
Scripps Research chemist devises new method to quantify protein changes
JUPITER, FL, January 5, 2011 — A scientist from the Florida campus of The Scripps Research Institute has devised a new method of analyzing and quantifying changes in proteins that result from a common chemical process. The new findings could provi…
Team creates novel vaccine that produces strong immunity against cocaine high
LA JOLLA, CA — January 4, 2011 — Researchers from The Scripps Research Institute, Weill Cornell Medical College, and Cornell University have produced a long-lasting anti-cocaine immunity in mice by giving them a unique vaccine that combines bi…
Scripps Research scientists identify key interaction in hepatitis C virus
JUPITER, FL, December 28, 2010 — Scientists from the Florida campus of The Scripps Research Institute have identified a molecular interaction between a structural hepatitis C virus protein (HCV) and a protein critical to viral replication. This ne…
Scripps Research scientist uncovers switch controlling protein production
JUPITER, FL, December 22, 2010 — A scientist from the Florida campus of The Scripps Research Institute has discovered a molecular switch that controls the synthesis of ribosomes. Ribosomes are the large machineries inside all living cells that pro…
Scripps Research scientists redefine the role of plasma cells in the immune system
La Jolla, CA — November 29, 2010 – For Immediate Release — A team of scientists from The Scripps Research Institute have uncovered a previously unknown regulatory mechanism in the body’s response to eliminate pathogens, such as bacteria and viru…
Reading the signs: Plants and animals found common ground in response to microbial threats
Though it’s been at least a billion years since plants and animals shared a common ancestor, they have through the eons shared a common threat in the form of microbes, including bacteria, eukaryotes and viruses. This has resulted in remarkably sim…
Scripps Research scientists identify first synthetic activator of 2 critical proteins
JUPITER, FL, November 19, 2010 — Scientists from the Florida campus of The Scripps Research Institute have identified a novel synthetic activator of a pair of proteins that belong to a protein family playing key roles in human metabolism and immun…
Scripps Research scientists identify new mechanism regulating daily biological rhythms
JUPITER, FL, November 9, 2010 — For Immediate Release — Scientists from the Florida campus of The Scripps Research Institute have identified for the first time a novel mechanism that regulates circadian rhythm, the master clock that controls the…
Scripps Research team ‘watches’ formation of cells’ protein factories for first time
LA JOLLA, CA — October 29, 2010 — For Immediate Release — A team from The Scripps Research Institute has revealed the first-ever pictures of the formation of cells’ “protein factories.” In addition to being a major technical feat on its own, t…
Scientists describe new approach for identifying genetic markers for common diseases
La Jolla, CA, October 28, 2010 — For Immediate Release — A group of researchers at The Scripps Research Institute and the Scripps Translational Science Institute has published a paper that reviews new strategies for identifying collections of ra…
Entire issue of scientific journal devoted to center headed by Scripps Research Scientists
LA JOLLA, CA, October 21, 2010 — A multi-institutional consortium led by The Scripps Research Institute scientists, the Joint Center for Structural Genomics (JCSG), is the sole focus of a special issue of the journal Acta Crystallographica Sectio…
Scripps Research study challenges conventional theory of modern drug design
JUPITER, Fl, October 7, 2010 — Scientists from The Scripps Research Institute have uncovered new evidence that challenges the current theory about a process key to the way modern drugs are designed and how they work in the human body.
The new st…
Scripps Research scientists develop novel test that identifies river blindness
LA JOLLA, CA — October 6, 2010 — For Immediate Release — Scientists from The Scripps Research Institute have developed the first screening method that rapidly identifies individuals with active river blindness, a parasitic disease that afflict…
Scripps scientists develop test providing new pathway for identifying obesity, diabetes drugs
La Jolla, CA, September 15, 2010 — Scientists at The Scripps Research Institute have designed a new molecular test that will allow researchers to look for potential drugs targeting a human metabolic enzyme believed to stimulate the appetite and pl…
Scripps Research scientists solve long-standing mystery of protein ‘quality control’ mechanism
LA JOLLA, CA — September 9, 2010 — Scientists from The Scripps Research Institute have solved a long-standing mystery of how cells conduct “quality control” to eliminate the toxic effects of a certain kind of error in protein production. The fi…