Tampa, Fla. (Feb. 22, 2011) — Transplanting human umbilical cord blood-derived endothelial progenitor cells (EPCs) has been found to “significantly accelerate” wound closure in diabetic mouse models, said a team of Korean researchers publishing …
Tag Archives | transplantation
First liver transplant patients receive experimental drug to prevent hepatitis C infection
Boston, Mass. — Following a successful Phase 1 study for safety, researchers at MassBiologics of the University of Massachusetts Medical School (UMMS) today announced the beginning of a Phase 2 clinical trial testing the ability of a human mono…
Metabolic syndrome found in 52 percent of patients after liver transplantation
Researchers from Israel have determined that more than half of liver transplant recipients develop post-transplantation metabolic syndrome (PTMS), placing them at greater risk for cardiovascular disease. Prior to transplantation only 5% of the patie…
New test announced for major killer of lung transplant patients
ANN ARBOR, Mich. — A lung transplant can mean a new chance at life. But many who receive one develop a debilitating, fatal condition that causes scar tissue to build up in the lungs and chokes off the ability to breathe.
University of Michigan …
New test announced for major killer of lung transplant patients
ANN ARBOR, Mich. — A lung transplant can mean a new chance at life. But many who receive one develop a debilitating, fatal condition that causes scar tissue to build up in the lungs and chokes off the ability to breathe.
University of Michigan …
Fat cells become useful stem cells in tissue reconstruction
Tampa, Fla. (Dec. 23, 2010) — Two studies appearing in the current issue
of Cell Transplantation 19(10) discuss stem cells derived from adipose (fat) cells and their potential use in plastic surgery and tissue reconstruction. The studies are now…
Organ procurement air transportation displays poor safety record
The transplant community was largely unaware of sub-standard transportation practices for donor organs until a number of fatal air crashes took the lives of transplant personnel, calling attention to procurement aviation safety. A new report highlig…
Obese children experience later mortality post liver transplantation
A new study from the University of Washington reported obese children are at increased mortality risk in later years following primary liver transplantation (LT). Pediatric patients who are thin or severely thin, experience an early mortality risk -…
King’s College London reveals promising techniques for extending the life of an organ transplant
Experts from the Medical Research Council (MRC) Centre for Transplantation at King’s College London, based at Guy’s Hospital, have revealed exciting new scientific developments for people with an organ transplant, intended to help prevent rejection …
Hispanics and Asians less likely to receive liver transplants
Researchers at the University of Michigan and Arbor Research Collaborative for Health, both in Ann Arbor, have identified geographic variation as a key factor accounting for disparities in access to liver transplantation among racial and ethnic grou…
Study identifies factors which predict alcohol use after liver transplantation
Patients who receive a liver transplant due to alcoholic liver disease need to demonstrate periods of abstinence and often attend addiction treatment before transplantation. However, alcohol use disorders can recur, as can other diseases requiring t…
Pretreatment increases liver transplant survival
Pretreating transplanted livers with the immune molecule interleukin-6 (IL-6) dramatically increased survival of rats receiving organs with fatty degeneration–a common condition in humans that typically reduces transplant viability. The results suggest a means of making it possible to use a higher percentage of available donor livers for transplantation in humans. With over three times as many Americans needing transplants as there are available donor livers, an effective approach to increasing the number of viable donor organs would help narrow the gap between demand and supply.
Gene signature identifies leukemia patients who should avoid transplants
An international team of researchers has used a gene test to identify certain patients with adult T-cell acute lymphoblastic leukemia (ALL) who can be successfully treated with chemotherapy alone and should not be subjected to the rigors of bone marrow transplants. The researchers found that these patients survived for at least three years after being treated with intensive chemotherapy. It was previously known that only slightly over half of the patients with this disease could be cured with chemotherapy. Adult ALL patients often undergo transplants in an effort to beat back the stubborn disease. Until now there was no way to identify those who have a more favorable outlook and shouldn’t undergo risky bone marrow transplantation.