Hepatocellular carcinoma (HCC) is the fifth most common malignancy in the world and is estimated to cause approximately half a million deaths annually. Undoubtedly, the best available treatment for all liver tumors is complete surgical resection. Ho…
Tag Archives | world journal of gastroenterology
T-regulatory lymphocytes in gastrointestinal cancer
T-regulatory lymphocytes (Tregs) are a subset of T lymphocytes that are involved in the mechanism of immunotolerance to self- and allo-antigens. Activity of these cells is one of the mechanisms of immune evasion of tumors, which inhibits the antitum…
New classification of sphincter of Oddi dysfunction
Sphincter of Oddi dysfunction (SOD) is a pathological syndrome that is usually classified into the biliary type or the pancreatic type according to the Milwaukee criteria. However, this classification has some drawbacks in clinical practice, some of…
Hepatic vein thrombosis following liver resection
Patients undergoing liver surgery have long been considered to be at low risk of venous thromboembolism. However, pulmonary embolism has recently emerged as an increasingly frequent and potentially fatal complication following liver resections.
A …
A diagnostic marker in hepatocellular carcinoma
E2F5 is a member of the E2F transcription factor family, and plays a key role in cell growth and proliferation. Overexpression of E2F5 has been reported in various human cancers, but not in liver cancer, and its biological implication is largely unk…
MRI: An accurate method to evaluate iron overload
Iron overload is a common and serious problem in thalassemic major patients. As iron accumulation is toxic in the body’s tissues, accurate estimation of iron stores is of great importance in these patients to prevent iron overload by an appropriate …
Seroprevalence of anti-HAV among patients with chronic viral liver disease
Hepatitis A virus (HAV) is an epidemiologically important virus with a worldwide distribution and causes acute hepatitis in humans. Acute HAV superinfection causes severe liver disease, acute liver failure and even higher mortality rates in patients…
Is different approach needed for acute diverticulitis in younger patients?
Acute diverticulitis is the most common complication of diverticular disease, and its clinical presentation varies from mild local inflammation to full-blown perforation. After resolution of an acute episode, the best management strategy is as yet u…
Hemolysis and intestinal injury
Hemolysis is not uncommon during cardiovascular surgery, resulting in elevated circulating levels of cell-free oxyhemoglobin (FHb). The effect of hemolysis on intestinal microcirculation and gut wall integrity is unclear.
A research article to be …
Small bowel blood flow in healthy subjects receiving low-dose aspirin
Low-dose acetylsalicylic acid (ASA) has been widely used for prevention of cardiovascular and cerebrovascular events. Several studies have shown that mucosal breaks caused by taking low-dose ASA occurred not only in the upper gastrointestinal tract …
Effects of chemoradiation therapy by using capecitabine on gastric cancer patients
Gastric cancer is a major cause of cancer deaths in the world. The outcome of large gastric tumors and those with lymph node involvement remains poor after surgical resection. The optimal adjuvant therapy after surgical resection remains to be deter…
New options for enteral nutrition in patients with severe acute pancreatitis
Severe acute pancreatitis (SAP) requires an adequate nutritional support. Enteral nutrition (EN) should be preferred to total parenteral nutrition in patients with SAP, as it is associated with reduced mortality and complications. However, in clinic…
How to control massive bleeding from the hepatic artery
Delayed hepatic arterial hemorrhage after pancreaticoduodenectomy (PD) is not a common but a fatal complication, occurring in 7% of all patients. Its ideal management remains unclear and controversial.
A research article published on August 7, 20…