RA modulates CKIs in TGF-?1-stimulated rHSCs

OUR GROUP. Retinoic acid (RA) increased the protein level of p16INK4a and induced p21Cip1/WAF1 protein expression; meanwhile, p27Kip1 was undetectable by immunocytochemistry in both control and RA-treated hepatic stellate cells (HSCs). However, RA had no influence on the mRNA levels of p16INK4a, p21Cip1/WAF1 or p27Kip1 as determined by in situ hybridization.

Full Text (World J Gastroenterol 2000;6:819-823)


Please enter your comment!
Please enter your name here

This site uses Akismet to reduce spam. Learn how your comment data is processed.