Antioxidant to retard wrinkles discovered

A new method for fighting skin wrinkles has been developed at the Hebrew University Faculty of Agriculture, Food and Environmental Quality Sciences.

In her doctoral research at the university, Dr. Orit Bossi succeeded in isolating a plant-based antioxidant that delays the aging process by countering the breakdown of collagen fibers in the skin. Dr. Bossi conducted her research under the supervision of Zecharia Madar, the Karl Bach Professor of Agricultural Biochemistry at the Hebrew University, and Prof. Shlomo Grossman of Bar-Ilan University.

Antioxidants operate against free radicals which cause a breakdown of many tissues in the body, including the skin. When found in small quantities in the body, free radicals are not harmful and are even involved in various physical processes. When there is an excess of free radicals, however, as occurs during normal aging or as a result of excessive exposure to ultra-violet radiation from the sun, the result, among other things, is a breakdown of the collagen and elastin fibers in the skin. When this happens, there is a loss of skin elasticity and the formation of wrinkles.

“A problem with many of the commercial antioxidants found today in the market that are said to retard the aging process is that they oxidize quickly and therefore their efficiency declines with time,” said Dr. Bossi. “Vitamin C, for example, oxidizes rapidly and is sensitive to high temperatures. This is also true of the antioxidant EGCG which is found in green tea, and vitamin E. As opposed to these, the antioxidant which I used in my research is able to withstand high temperatures, is soluble in water, and does not oxidize easily and thus remains effective over time.”

Dr. Bossi is looking towards a new generation of cosmetic products which will not only combat wrinkles but will be more effective against deeper levels of skin wrinkles than current products. Dr. Bossi did not reveal the plant source she used to derive the antioxidant, since the research is in the process of being patented.

In her research, Dr. Bossi conducted experiments on mice skin tissue, which, she says, resembles that of humans. She applied her antioxidant on two skin cell groups – those which had been exposed to the sun’s rays and received her antioxidant and those which also had been exposed to sun but did not receive the antioxidant. The untreated cells showed a rise in free radicals causing wrinkles, while those cells which had been treated showed no significant increase in the free radicals level.

http://www.huji.ac.il


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22 thoughts on “Antioxidant to retard wrinkles discovered”

  1. I am self medicating by using a small juicer to extract the antioxidants and live enzymes from fruits and veggies, specifically kale as it removes its body weight of waste from your body.

  2. To the first two commentators:

    When YOU conceive, research and develop a product which benefits a huge number of people – and for which they are willing to compensate you – and then you refuse to take the money …
    Then get back to us.
    Yeesh.

  3. Aging cannot be stopped but it can be delayed by following a healthy outlook and lifestyle. Products like Bioastin will compliment your positive outlook in life. Look young and feel young by thinking positive. 550 times the antioxidant power of Vitamin E and 10 times the antioxidant power of Vitamin A.

  4. If the new compound acted as an effective sunscreen the UV wouldn’t penetrate the skin to cause the damage represented by the free radicles!
    How do you measure the UV inside the tissues?
    Ron Horgan.

  5. I agree with what you said. I’m 45 and still pass for around 30. But so what if I look great on the outside. Inside I’m completely falling apart, LOL! Stomach ulcer, heartburn, degenerative disk disease in my spine, hypothyroid, vitiligo, sciatica, bad knees, bad back, everything hurts. I feel like I’m 95 on the inside. So I’ll buy the cream and be a really good looking corpse. LOL.

  6. So how old are these mice they are experimenting with?
    I love my wrinkles, I have earned everyone of them.. I adored my grandparents when I was young, probably why I feel comfortable in my skin now…
    Anti-wrinkle creams in the past have consisted of skin irritants.. so your skin would swell, and thus leave the wrinkles behind..
    Did you ever notice guys may have wrinkles.. or is it just the women.. huh?
    It’s like, there are no difficult men, just difficult women..

  7. A massage therapist told me to buy a tennis ball and roll around on it where it hurts the most for deep tissue massage.

    Belly dancing can help anything you have wrong with you because you are laughing when you try to do all the isolated (isometric even) moves.

    Laughter may make wrinkles, but I would like to have laugh lines 10 million times more than frown lines!
    Charlotte
    kudzus

  8. Get over it. This is just more lotion that will be sold by Dove. How much is it, like $10 a bottle? Big deal. It’s not like a cure for AIDS or anything…no one is going to die of wrinkles.

    Obviously if people are dying of a disease and a cure is invented, assistance should come before profit. Whoever came up with it will duly benefit in time. This is a cosmetic issue though.

  9. I generally avoid reading these comments……
    because mud slinging always ensues.
    Amidst a few smart, sincere and/or well thought out comments, there always exists the toxic nay-sayer.
    Surely it is possible to express a contrary thought or opinion without resorting to such measures. Venomous replies only negate what you are really trying to convey.
    Might I suggest you not only brush up on your debating skills, but also your vocabulary.

  10. The comment regarding the inability to patent a naturally occuring substance is misleading. Actually one can patent a naturally occurring substance. Consider, if I discover that Vitamin C is a great fuel additive that keeps gasoline from ‘going stale’ (it does become gummy by the way), I can patent Vitamin C as a fuel additive.

    Thus, if someone finds that a naturally occuring substance keeps one from becoming wrinkled, then that substance can be patented for use in anti-wrinkle creams and pills, etc.

    I second motion regarding paying for products that result from basic R&D. If researchers, or their investors, don’t get a return on their investment, they have no incentive to do the research in the first place.

    Or, they will work like crazy to keep their discovery secret, which will hurt further research by others. When Gutenberg printed his books, he tried to keep his process a secret. The printing press was too big to hide well, but the recipe, using naturally occuring substances, of course, for his ink, the best there was for centuries, was lost when he died. A crying shame, all for the want of a good patent!

    This is the bargain that society is making with inventors and researchers. A patent gives the right to a legal monopoly to a discovery for 20 years, in exchange for FULL disclosure regarding that discovery. Society benefits with faster pace of development, without fear that secret discoveries may be lost, and researchers/inventors benefit with a fair return for a reasonable period of time.

    –Candice H. Brown Elliott

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