University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed. Their discovery, to be published in PLoS Online on December 26, opens the door to treating and curing conditions that lead to excessive tissue scarring such as viral hepatitis, fatty liver disease, cirrhosis, pulmonary fibrosis, scleroderma and burns.
Six years ago, the UC San Diego School of Medicine research team discovered the cause of the excess fibrous tissue growth that leads to liver fibrosis and cirrhosis, and developed a way to block excess scar tissue in mice. At that time, the best hope seemed to be future development of a therapy that would prevent or stop damage in patients suffering from the excessive scarring related to liver or lung disease or severe burns.
In their current study, Martina Buck, Ph.D., assistant professor of medicine at UCSD and the Veterans Affairs San Diego Healthcare System, and Mario Chojkier, M.D., UCSD professor of medicine and liver specialist at the VA, show that by blocking a protein linked to overproduction of scar tissue, they can not only stop the progression of fibrosis in mice, but reverse some of the cell damage that already occurred.
In response to liver injury – for example, cirrhosis caused by alcohol – hepatic stellate cell (HSC) activated by oxidative stress results in large amounts of collagen. Collagen is necessary to heal wounds, but excessive collagen causes scars in tissues. In this paper, the researchers showed that activation of a protein called RSK results in HSC activation and is critical for the progression of liver fibrosis. They theorized that the RSK pathway would be a potential therapeutic target, and developed an RSK inhibitory peptide to block activation of RSK.
The scientists used mice with severe liver fibrosis – similar to the condition in humans with cirrhosis of the liver – that was induced by chronic treatment with a liver toxin known to cause liver damage. The animals, which continued on the liver toxin, were given the RSK-inhibitory peptide. The peptide inhibited RSK activation, which stopped the HSC from proliferating. The peptide also directly activated the caspase or “executioner” protein, which killed the cells producing liver cirrhosis but not the normal cells.
“All control mice had severe liver fibrosis, while all mice that received the RSK-inhibitory peptide had minimal or no liver fibrosis,” said Buck.
Buck explained that the excessive collagen response is blocked by the RSK-inhibitory peptide, but isn’t harmful to the liver. “The cells continue to do their normal, healing work but their excess proliferation is controlled,” Buck said. “Remarkably, the death of HSC may also allow recovery from liver injury and reversal of liver fibrosis.”
The researchers found a similar activation of RSK in activated HSC in humans with severe liver fibrosis but not in control livers, suggesting that this pathway is also relevant in human liver fibrosis. Liver biopsies from patients with liver fibrosis also showed activated RSK.
The study expands on work reported in 2001 in the journal Molecular Cell announcing that a team led by Buck had found that a small piece of an important regulatory protein called C/EBP beta was responsible for fibrous tissue growth, or excessive scar tissue following injury or illness. When normal scarring goes awry, excessive build-up of fibrous tissue can produce disfiguring scars or clog vital internal organs and lead to serious complications. Buck and colleagues developed a mutated protein that stopped this excessive fibrous tissue growth.
“Six years ago, we showed a way to prevent or stop the excessive scarring in animal models,” said Buck. “Our latest finding proves that we can actually reverse the damage.”
Worldwide, almost 800,000 people die from liver cirrhosis each year, and there is currently no treatment for it. Excessive tissue repair in chronic liver disease induced by viral, toxic, immunologic and metabolic disorders all result in excessive scar tissue, and could benefit from therapy developed from the UCSD researchers’ findings.
The research was supported by grants from the National Institutes of Health, the Department of Veterans Affairs and UCSD’s Medical Research Foundation. Buck is the recipient of a Howard Temin Award from the National Cancer Institute.
From http://www.ucsd.edu
I never knew cannabis oil was indeed wonderful and very effective in the treatment of cancer “if not by the government and so called rules to regulate cannabis dad would still have been alive. Thanks to the new policy of legalizing cannabis in my state and have even lost my wife’s kidney cancer, and it was really shocked and surprised when I see a lot of documentary on how the cannabis oil had helped many people to whom His family thought they never could do next undergoing several “Chemo” from the department of my heart, and I have to say a word of appreciation to Dr. Brown Nelson for timely intervention in the lives of my wife suffering from kidney cancer. As I write this testimony in this blog my wife is so strong and healthy even though you have not completed the total dosage “for cannabis and medical consultation opportunity and get in touch with him if you are a cancer patient through their email: ([email protected]) so you can lit more details
Treatment Regine:
I have a pretty big tolerance for marijuana, so I started off with a full grain of rice sized amount of oil instead of a half grain. I gradually increased the dosage every night until I reached a full gram each night. The standard protocol for Rick Simpson Oil is ingesting a total of 60 grams over the course of 2-3 months, but I had 70 grams in total for safe measure. I used the excess as a topical skin care treatment, attacking the visible brown spots on my face and neck.
3 months later, my cancer was in full remission. Within 4 months, I am cancer-free and officially received a clean bill of health from my doctors. What they don’t know is that the majority of my treatment was using the Rick Simpson Oil. I did use some of the medication they prescribed, but it was in combination with the oil.
I am elated I want to continue sharing with people who are experiencing what I went through that there is absolutely hope and a cure out there. They just need to be proactive and aggressive with treatment, not wait until it is too late. Get your medication at Phoenix Tears via Email: ([email protected])
In addition to being an effective cancer fighter, there are some nice side effects that come from using the Rick Simpson oil, for instance, I no longer need to take any pain killers. Just one or two drops of the oil will ease the pain and help you sleep like a baby. Best of all, its natural . . . Thanks to all the staff at Amsterdam’s Garden who guided me throughout this journey. You guys are awesome!
, It is was a pleasure that i thank Dr.Rick Simpson for saving my dying husband with his cannabis oil.
We already lost hope for a better the report came that my husband cannot go for more Chemo anymore. But after so many research online, I gained a lot about the cannabis oil that i bought from Dr.Rick Simpson whose contact I got online on reading a testimony about his past works and glory, The medication was delivered to me within 24 hours by the UPS delivery service after procurement. My husband has completed his treatment, unquenchable joy to all as my husband is cured of his stage 4 lungs cancer within 90 days of treatment. Thanks to all, today i acknowledge the greatness of cannabis oil and to those that wish to purchase the medication contact Dr.Rick Simpson at: [email protected]
Cannabis Oil is the a medication for cancerous disease [email protected]
I still don’t know the right words to express my Gratitude to Rick Simpson and his wonderful cannabis oil that cured my ailment. In May 2014 i was diagnosed of Melanoma Cancer, it affected my Skin, intestines and eye.. i went for treatment but to no avail, my family advised the rick hemp oil for my ailment, at first i didn’t want to purchase the oil, because i had doubts about it curing my cancer, but after reading about it and doing researches online, i succumbed to the idea, and indeed it was a wonderful one, the cannabis oil successfully cured my cancer!!! after Three months.
Now i am Hale and Healthy…….. you can contact Rick Simpson on
[email protected]
Other Natural Things You Can Do That Could Help
When people come to me for oil to treat their cancer, the first thing I tell them to do is change their diets. Try to stay away from animal protein as much as possible, since such protein promotes cancer growth. Get a juicing machine and start eating as many raw fruits and vegetables as possible, since plant protein fights the growth of cancer. Stop using sugar and replace its use with natural sweetener’s like raw honey. Get the patient’s PH up as quickly as possible, cancer likes an acidic environment and when you raise the body’s PH it makes it hard for cancer cells to survive. Also start eating the seeds from two apples everyday, this will give you a good daily dose of B17 also known as laetrile. B17 in its own right has a pretty good track record in the treatment of cancer and there are other natural things such as wheat grass, that you may find of benefit as well. Many people who have used the oil to treat their cancers did not change a thing, but the oil still worked its magic and they were healed.
But if you have a serious condition like cancer I think its a good idea to take other natural things that may help the oil eradicate the cancer and give you a better chance to survive. We are willing and ready to help the patient with all the medical help that are available to see he/she is back to life healthy and free of all this terrible diseases.
You will need the full treatment of 60 gram to eradicate the cancer from body totally.
To secure an order for my medication, please go to our email [email protected] for more news at
email [email protected]
You have to provide below information for your order.
Patient’s Name:
Patient’s Country:
Patient’s City/State:
Patient’s Postal Code:
Patient’s Phone Number:
Patient’s Delivery Address:
I want to thank rick simpson and the entire management of ricksimpsonmedicalservices for their life saving cannabis oil that cured my wife’s thyroid cancer,the doctor told me there was little he could since despite all the chemo and radiation,she wasn’t responding to treatment.so a friend of mine came to our rescue by ordering this cannabis oil from rick simpson medicals services which he said rick has been helping patients fight against cancer of various types so we decided to give it a try,so far my wife is improving very well and presently she can walk around the house all by herself.i felt it’s necessary i let others especially those suffering from this acute disease that once you have a good cannabis oil,it can really give a second chance at life.if you happen to be in dying need of this cannabis oil,you can contact the foundation who supplied us with this email:[email protected]
My Mother was diagnosed with breast cancer and she was at the point of death, with cancer of the Breast in it final stage is now back alive and she is so healthy now. Thanks to Dr rick Simpson cannabis oil that we bought a: [email protected], the Hemp oil was you can contact for your medication at: [email protected]
My mother was diagnosed with Stage IV cervical cancer, then i wasted a lot of money for years for treatment,until i saw in the [email protected]
in the internet that cannabis oil can cure all cancer,i tried to look for a way to get the Rick Simpson Oil and finally a friend of mine helped via email:[email protected]
told me how to reach him and get the oil,i was able to email him and bought the oil,my mother started taking it on 12th January and glory be to God she was healed in April after her last scan,i would want to thank Rick for the time he spent in getting this oil to save lives his email is : [email protected]
the oil works for all type of cancer and it is worth it. Mobile: +1 312 835 3384
(+44) 703 194 2647
I want to use this medium to applause Rick Simpson for curing my Fiance cancer with his
cannabis oil, my fiance has been suffering from colorectal cancer for
the pass three years now, but ever since we started using the Rick
Simpson Cannabis oil for the past 3 months and instruction on how to
use it, my fiance has fully recovered from her colorectal cancer. The
Rick Simpson cannabis oil has proven a great success on cure for
cancer with his cannabis oil and I give him a lot of credits, because
my fiance cancer was cured within 4 months of successful treatment,
am getting married to my fiance as her colorectal cancer has been
totally cured with Rick Simpson cannabis oil which we
purchase:bef, It has been 4 months now
of the successful cure of my fiance colorectal cancer and ever since
my fiance stop treatment and her health has been perfect and
marvelous. as I am writing this testimony to notify you that my fiance
has been completely cured of her cancer. any one out there who need
help, please feel free to get in touch with
Rick at:[email protected]
Warm appreciation to Dr. rick simpson for curing my Breast cancer with cannabis oil. I really appreciate your help in bring back my lost life with the help of his high quality Cannabis Oil, i am so grateful to you Dr for all the love and concern that you showed me and i would keep on giving my testimony about your Cannabis oil and how is cures Cancer within 90 days of treatment. it just like a Miracle that has happened to me with full recovery from cancer and i am free from Cancer. Thanks be to God Almighty for sending you my way Dr, i hope and know that you would keep on putting smiles on world at large with this great medication. email:[email protected] for all solution to cancer and other diseases. Those facing health challenges should go for cannabis oil to ensure the absolute cure of all kinds of cancerous diseases. For hopes and help, kindly contact Dr.rick simpson for full knowledge about the medication and Services to you. Dr. email:[email protected] for all solution to cancer and other diseases.
Julie Fred
U.S.A
This is so great am alive to testify the good work of hemp oil and its miracle healing.
In April 10th 2012 i was diagnosed of breast cancer and bone cancer when the doctor told me it was already too late for me, that i have only ten months on earth to live. I shared tears and all hope was gone thinking that i will just sleep and go just like that.
My mom came to visit me in Serbia two months later and bought me some hemp oil product saying that it works well on cancer, ever since she told me about the benefits and encourage me to use the medication. I have been on treatment for the past 4 months now which was the required treatment plan for me.
Last week, I went to hospital to do my test and to God be the glory my cancer was not found there anymore. I have been cured with Rick Simpson hemp oil which my mother had bought for me.
My family in forever grateful to Rick Simpson Cannabis Oil.
Last week my mom gave me his email and phone number which i contacted him in person and thank him for the life saving.you can contact him with this email [email protected]
My story has to do with the healing power of Rick Simpson cannabis oil.”My sister Khloe, age 65, was diagnosed with Bone Cancer on the inside of her backbone 2 years ago, which had metastasized from breast cancer she didn’t know she had. I prayed for a total healing with NO operation, no chemo and no radiation. not everyone has had the experience of knowing Rick Simpson as their Healer… but they can! Rick Simpson, father of all natural hemp.
May the grace of God be upon Rick for his good work and courage; and with his Hemp we are healed”.
Early this year i traveled to Europe( Slovak) to visit a good friend of mine when i heard Rick was around so i traveled to him and meet him one on one and purchase the healing oil from him, now am so happy and filled with joy that my sister is no longer a cancer patient and she’s completely healed with his miracle healing oil. The doctor himself confirmed to us on Tuesday last week that my sister Khloe is fully OK. No sign of cancer in her bone or breast again….Wow…Am so so happy that my family and I have been thanking Rick for his good work of saving this world with his cannabis oil. Please people i don’t know how to thank him enough so am dropping his contact here*** [email protected] *** +447024078253 ***, am begging if you can spear 5 minutes of your time and please help me to thank him, he is truly a hero of this world and i pray for God’s strength and wisdom upon him.
My name is Mrs Tracy Brown from Canada,I never believe My husband will see 2014 It is with pleasure that i thank Rick Simpson for saving my dying husband with his cannabis oil.
We already lost hope for a better life when the report came that my husband cannot go for more Chemo anymore. But after so many research online, I gained a lot about the cannabis oil that i bought from the Rick Simpson whose contact I got online on reading a testimony about his past works and glory, The medication was delivered to me within 24 hours by the UPS delivery service after procurement. My husband has completed his treatment, unquenchable joy to all as my husband is cured of his stage 4 lungs cancer within 90 days of treatment. Thanks to all, today i acknowledge the greatness of cannabis oil and to those that wish to purchase the medication contact Rick Simpson at: [email protected] for help.
Cannabis Oil is the a medication for cancerous disease.
Warning:
There is no Dr. Nathan Kisper, Dr. Mike Henderson, Dr. Sedney Carey, Dr. Mac Donnald, Dr. Bryan Vance etc.. Only the big scammers hiding behind these names. Unfortunately I am the one of their victims. Be careful and don’t trust them and in any of their “stories”!!!
Warning:
There is no Dr. Nathan Kisper, Dr. Mike Henderson, Dr. Smith Williams, Dr. Sedney Carey, Dr. Mac Donnald, Dr. Bryan Vance etc.. Only the big scammers hiding behind these names. Unfortunately I am the one of their victims. Be careful and don’t trust them and in any of their “stories”!!!
Hello Good Friends of the world, I am Marian Carson, from Texas, U.S.A who suffer from breast and lungs cancer, basically a Death Sentence on my life and i thank you all my friends for your prayer and concern toward my life and i pray for God to be with you all. You my dear and favorite friends gave me Doctor Henderson contact, guaranteeing me that he was the one to help me cure my cancer and Thank God to the Doctor Henderson who God has sent to help me through my friends cure the terrible cancer illness which has almost taken my life. The thoughts of having Breast and lungs Cancer burns and itches simultaneously in my heart that i was dead alive. I heard that Hemp Oil could help, my friend gave me assurance that Doctor Henderson will cure my cancer, for he has done it for several of them and for the price i was willing to try anything that would save my My Life, what I found out was astonishing! It was instantly getting better and better after 60 days of using Doctor Henderson Hemp Oil and most of the virus are gone and just little medication left for me. I am very grateful to Doctor Henderson for Selling the Hemp Oil for me and his Medical Advises, for all those that have problems with Cancer Please Please Kindly let the Doctor Know, he will help you with all you need to cure your cancer, he is trust lovely, caring,wealthy and sincere. Talk to him with this Email: [email protected] He saved my Life that is why i will keep on giving his testimonies. Marian Carson Texas, United State of America. contact the Best Doctor: [email protected] he will save your life and your family.
What are the latest results of testing of RSK inhibitory peptide, for reversal of liver cirrhosis? Has there or will there be any clinical testing using humans as test subjects? Will clinical testing be made available to human volunteers? Please provide me with any information and/or test results. I have Alcoholic Liver Cirrhosis, so my interest is for myself personally…and for anyone else that may be helped by this disclosure.
Thank you.
My son, who is 28, was diagnosed with cirrhosis and we almost lost him. He was in and out of hospitals due to the other problems that arise when your liver doesn’t work. His kidneys started failing and he developed bilateral pfnemonia. He has had two pancreatic attacks that he says feel like the most crucial pain from his chest to his back. He was put on Xifaxan 550 mg twice a day and has taken it for two months twice a day. It is extremely expensive, 30 days cost $1,600. This medication is a miracle worker. He has his color back and his billirubin has gone down to a “2” when it had been in the “35” or so. His doctor says he no longer has cirrhosis of the liver and can live a healthy normal life. He has stopped taking the medication and is only on folic acid and Thiamine and Prilosec. I thank God and whoever invented the Xifaxan for it is a miracle pill. 7/10/12
All I hear is this bullshit articles that researches found this and that and done it to animals and there usually dated many years backwards. So where are these miracle cures? Why arnt they being used on people why isnt this on the front page of the news?
Need A Cure For Cerrhosis For A Woman With 2 Months To Live Please Write Back ASAP!!!!!!! Please
hi. it’s mike again. just an update. LISTEN UP!
I have started, based upon the SUCCESSFUL Results of a 2 Yr. Clinical Trial,
by my Dr.’s agreement and prescription 8mg Candesartan name brand, ATACAND, only available, no generic in U.S. This is 11 years on the market, safe, shown to REVERSE LIVER FIBROSIS. $90 for 30 days at walmart …with my insurance, only a $30 copay.
Also, Actigall, 600 mg per day (prescription only)…Known as Urso, UDCA, available $37 at Walmart.
Look up on google or nih alcoholic fibrosis candesartan …..
Average liver fibrosis decrease of 30%.
This is the real deal. Atacand, an Angiotensin 2 receptor blocker, is better than ACE inhibitors. Atacand is used for heart patients also, a blood pressure reducer. Please, please, surround yourself with accurate, current information. Focus on the good news re: cirrhosis, steatohepatitis, fibrosis….fatty liver, nash, nafld.
Try liver fibrosis at SCIENCE DAILY.com . Also, the World-leading NewsRx.com.
Tell or print out….and take to) your Dr. about the things you find, especially at nih.gov. Get pushy. My general practice Dr., not my Hepatologist, was the person I approached with the physical printout. He admitted then he had heard “they” were working on this approach.
We’re in the Best Time to have to deal with liver disease yet. Better than 2 years ago. Much better than last year.
p.s. Alpha lipoic is now shown to Reverse Liver Fibrosis!!! $7 Walmart. Research this, as always.
We’re gonna make it after all!!! God Bless. mike