New evidence that chili pepper ingredient fights fat

Capsaicin, the stuff that gives chili peppers their kick, may cause weight loss and fight fat buildup by triggering certain beneficial protein changes in the body, according to a new study on the topic. The report, which could lead to new treatments for obesity, appears in ACS’ monthly Journal of Proteome Research.

Jong Won Yun and colleagues point out that obesity is a major public health threat worldwide, linked to diabetes, high blood pressure, heart disease, and other health problems. Laboratory studies have hinted that capsaicin may help fight obesity by decreasing calorie intake, shrinking fat tissue, and lowering fat levels in the blood. Nobody, however, knows exactly how capsaicin might trigger such beneficial effects.

In an effort to find out, the scientists fed high-fat diets with or without capsaicin to lab rats used to study obesity. The capsaicin-treated rats lost 8 percent of their body weight and showed changes in levels of at least 20 key proteins found in fat. The altered proteins work to break down fats. “These changes provide valuable new molecular insights into the mechanism of the antiobesity effects of capsaicin,” the scientists say.

ARTICLE FOR IMMEDIATE RELEASE

“Proteomic Analysis for Antiobesity Potential of Capsaicin on White Adipose Tissue in Rats Fed with a High Fat Diet”

DOWNLOAD FULL TEXT ARTICLE

http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/pr901175w

CONTACT:

Jong Won Yun, Ph.D.

Department of Biotechnology

Daegu University

Kyungsan, Kyungbuk

Korea

Phone: 82-53-850-6556

Fax: 82-53-850-6559

Email: jwyun@daegu.ac.kr

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Get more stuff like this
in your inbox

From anti-aging to the search for alien life, we promise to never bore.