Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder that shares clinical similarities with BHD. TSC results from germline mutations in the Tsc1 or Tsc2 gene, affecting multiple organs, including the kidney and lung. In the kidney, lesions such as multiple renal cysts and renal cell carcinoma can occur. In the lung, patients can develop multifocal micronodular pneumocyte […]
Lack of Tsc2 in Mesenchymal Cells Causes Kidney Cysts and Defective Lung Alveolarization
The material in this press release comes from the originating research organization. Content may be edited for style and length. Want more? Sign up for our daily email.