Scientists ‘Write’ New Learning Patterns Directly into the Human Brain

In a development that bridges science fiction and reality, researchers have demonstrated a way to inscribe new patterns of brain activity that enable learning – all without surgery or physical manipulation. The technique, which uses real-time brain imaging and neural feedback, successfully taught participants to recognize new visual categories without explicit instruction.

Published in Proceedings of the National Academy of Sciences | Estimated reading time: 5 minutes

“With our method not only can we nudge complex patterns around in the brain toward known ones, but also—for the first time—write directly a new pattern into the brain and measure what effect that has on a person’s behavior,” explains lead author Coraline Iordan, assistant professor of brain and cognitive sciences and neuroscience at the University of Rochester.

Rewriting the Rules of Learning

Traditionally, learning occurs when our brain changes through experience, study, or instruction. This new approach, developed by researchers at Rochester, Yale, and Princeton, takes a radically different path. Rather than teaching participants what to learn, the scientists directly modified how their brains processed visual information.

The study participants lay inside an fMRI machine, viewing abstract shapes projected onto a mirror. These shapes would pulse or wobble until the participant’s brain activity matched a pattern pre-selected by the researchers. Success in achieving the desired brain state was rewarded with monetary incentives over six daily sessions.

What makes this study particularly remarkable is that participants learned to recognize new categories of objects without ever being explicitly taught what those categories were. As Princeton cognitive neuroscientist Jonathan Cohen notes, the research demonstrates that implicit processing – responding to information meaningfully outside of awareness – extends to forming entirely new neural representations.

Key Terms

Neural Feedback
A process where individuals receive real-time information about their brain activity, allowing them to learn to control it.
fMRI (Functional Magnetic Resonance Imaging)
A technique that measures brain activity by detecting changes in blood oxygen levels, showing which parts of the brain are active.
Implicit Processing
The brain’s ability to respond meaningfully to information without conscious awareness of that information.

Test Your Knowledge

What made the learning process in this study unique?

Instead of teaching participants through traditional methods, the researchers directly modified how their brains processed visual information, creating new learning patterns without explicit instruction.

How did participants receive feedback during the experiment?

They watched abstract shapes that would pulse or wobble until their brain activity matched the pattern researchers had selected, at which point the wobbling would stop.

What role did the fMRI machine play in the experiment?

The fMRI provided real-time monitoring of brain activity, allowing researchers to track when participants achieved the desired brain patterns and provide immediate feedback.

How does this research demonstrate implicit processing in the brain?

Participants learned to recognize new categories without explicit awareness of those categories, showing that meaningful learning can occur outside of conscious awareness.


Enjoy this story? Subscribe to our newsletter at scienceblog.substack.com.


Substack subscription form sign up