{"id":1828,"date":"2021-09-28T11:45:30","date_gmt":"2021-09-28T11:45:30","guid":{"rendered":"https:\/\/horizon.peachpuff-wolverine-566518.hostingersite.com\/?p=1828"},"modified":"2021-09-28T11:45:30","modified_gmt":"2021-09-28T11:45:30","slug":"getting-fit-to-fight-cancer","status":"publish","type":"post","link":"https:\/\/scienceblog.com\/horizon\/1828\/getting-fit-to-fight-cancer\/","title":{"rendered":"Getting fit to fight cancer"},"content":{"rendered":"
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Survival rates for cancer are improving, but it is still the leading cause of death<\/a> by disease for those over one year of age in the European Union (EU). Could exercise hold one of the keys to combatting cancer?\u00a0 And if so, how much physical activity is needed to show real benefits in both children and adults?<\/strong><\/p>\n<\/div>\n<\/div>\n

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Thanks to medical advances, cancer patients young and old can look forward to a better quality of life. However, despite all the progress made, the numbers remain disheartening. This is especially true for children and adolescents. According to the European Society for Paediatric Oncology,\u00a0every 15 minutes, a family in Europe gets the shocking news that their child has cancer<\/a>.<\/p>\n

The evidence keeps rolling in. Exercise is one way to address this difficult fact. But exercise might be one of the last things on the mind of a person who has been diagnosed with cancer.<\/p>\n

Can exercise become one of the most important cancer treatments for the young, and empower them to live longer, healthier lives?<\/p>\n

Physical inactivity is one of the most common side-effects of cancer treatment in children and adolescents. In adults, this side-effect is dealt with through an adapted exercise therapy called exercise oncology that is becoming more and more recognised as a treatment option. Focusing on the entire body, it uses a broad range of activities, from breathing, balancing and aerobic exercises to stretching and strength training.<\/p>\n

Exercise therapy and digital health technology <\/strong><\/p>\n

\u2018Exercise intervention studies in adult cancer patients have shown the beneficial effects of physical exercise on their muscular and cardiorespiratory performance during and after medical treatment,\u2019 said Prof. Dr J\u00f6rg Faber, head of the Childhood Cancer Centre at University Medical Centre Mainz, Germany. \u2018Furthermore, those benefits are associated with a significant improvement in patients\u2019 physical and mental health over time, and a reduction in frequent side-effects, including fatigue.\u2019 Despite its success with adults, exercise oncology has not been tailored to younger patients.<\/p>\n

More importantly, there is little evidence on whether exercise oncology can improve the lives of children and adolescents with cancer. According to Sandra St\u00f6ssel, exercise scientist and coordinator of the paediatric exercise oncology programme at the Childhood Cancer Centre, few scientific studies have been conducted on how it benefits the physical and mental wellbeing of childhood cancer patients.<\/p>\n

Many childhood cancer patients in the EU don\u2019t have access to adapted exercise training to achieve a sufficient physical activity level.<\/p>\n

One study, carried out at University Medical Center Mainz, indicated that exercise oncology can have positive effects. \u2018Many childhood cancer patients in the EU don\u2019t have access to adapted exercise training to achieve a sufficient physical activity level,\u2019 added physician Marie Neu, coordinator of the Childhood Cancer Centre. \u2018Exercise training has to be adapted to the different physiology and social environments of children.\u2019<\/p>\n

More research and a bigger sample size are needed for definitive proof. Knowing how much exercise is enough to make a tangible difference is also important.<\/p>\n

Prof. Dr Faber and his two colleagues are coordinating the largest study to date into the effects of exercise on the successful treatment of children with cancer as part of the FORTEe project. They are trying to come up with the right exercise dose \u2013 the intensity and frequency that need to be adapted individually. In total, 450 subjects aged 4 to 21 suffering from any type of cancer will participate in a trial while undergoing intensive cancer treatment.<\/p>\n

Project partners Oxford Brookes University and German small- and medium-sized enterprises Nurogames and Pixformance Sports have developed augmented reality (AR) and an exercise app that will be adapted and used in the trial. AR makes exercise more effective and personalised, while the app selects rehabilitation exercises based on patient age and individual needs. Nine hospitals across Europe (Denmark, France, Germany, Italy, Slovenia, Spain, the UK) will carry out a personalised exercise programme with the cancer patients.<\/p>\n

Thanks to these digital technologies, home-based, family-centred telemedical care will be integrated into cancer treatment.<\/p>\n

\u2018This is an essential step towards implementing personalised exercise oncology as an important, novel supportive therapy for cancer patients, and possibly enhancing the physical and mental health of children, adolescents and young adults in the EU and beyond,\u2019 observed Prof. Dr Faber. \u2018Potentially, exercise therapy will be established as a standard of care for these cancer patients in the future.\u2019<\/p>\n

In 2020, over 156,000 people died from colorectal cancer (CRC)<\/a> in the EU. It is the second most common type of cancer. Bente Klarlund Pedersen, professor of integrative medicine at the University of Copenhagen, Denmark, aims to demonstrate that regular exercise can delay or decrease the risk of tumours recurring in CRC patients who develop liver metastases. There is overwhelming data to support this. The problem is that this data is only available from pre-clinical trials. \u2018We have yet to truly translate promising observations into specific clinical settings,\u2019 stated Prof. Pedersen.<\/p>\n

Similar to children with cancer, patients whose cancer has spread from their colon or rectum to the liver are very underrepresented in exercise oncology research.<\/p>\n

\u2018Integrating exercise strategies into standard treatment may hold untapped potential in this population for improving disease outcomes, the impact of different symptoms on them and quality of life,\u2019 explained Prof. Pedersen, who is also director of the Centre of Inflammation and Metabolism and the TrygFonden Centre for Physical Activity Research at Rigshospitalet, Copenhagen University Hospital.<\/p>\n

She will also look into identifying the optimal exercise dose by researching the differences in frequency, duration and intensity of exercise for CRC patients as part of the POET-mCRC<\/a> project. Two doses \u2013 moderate and high \u2013 will be used to examine if additional benefits can be achieved with a higher training dose.<\/p>\n

CRC patients will participate in a 6-month training programme that involves either 300 or 150 minutes of exercise per week. Changes to their overall physical fitness and immune system will be assessed before and after this training period. The delay in formation of new tumours during this period will also be assessed.<\/p>\n

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The shortage of concrete evidence is lacking here, as well. \u2018Exercise can help maintain a patient\u2019s muscle mass and strength,\u2019 noted Prof. Pedersen. \u2018We know that exercise decreases the risk of 13 different cancers, including colon and breast cancer, but little research has been performed so far to show if exercise training prevents cancer from returning following the removal of tumours.\u2019<\/p>\n

Cancer concerns us all <\/strong><\/p>\n

The Commission intends to build a strong European Health Union<\/a> where all 27 Member States collaborate to improve prevention, treatment and aftercare for diseases such as cancer. There are several initiatives to make this possible. One is Europe\u2019s Beating Cancer Plan<\/a>, the EU\u2019s response to the urgent need for a renewed commitment to cancer prevention, treatment and care. Another is the Horizon Europe mission to conquer cancer<\/a>.<\/p>\n

There is no denying that an active lifestyle may help prevent people from getting cancer. Now we just need more concrete evidence that different forms and levels of exercise not only help patients survive, but also thrive during and after a cancer diagnosis. Professors Faber and Pedersen, together with their research teams, will be seeing to that in the near future.<\/p>\n

The research in this article was funded by the EU. If you liked this article, please consider sharing it on social media.<\/p>\n<\/div>\n<\/div>\n

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More info<\/div>\n
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FORTEe<\/a><\/p>\n

POET-mCRC<\/a><\/p>\n

Europe\u2019s Beating Cancer Plan<\/a><\/p>\n

Mission area: Cancer<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Survival rates for cancer are improving, but it is still the leading cause of death by disease for those over one year of age in the European Union (EU). Could exercise hold one of the keys to combatting cancer?\u00a0 And if so, how much physical activity is needed to show real benefits in both children … Read more<\/a><\/p>\n","protected":false},"author":298,"featured_media":1829,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"generate_page_header":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[12,112],"tags":[],"class_list":["post-1828","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","category-ict"],"yoast_head":"\nGetting fit to fight cancer - Horizon Magazine Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/scienceblog.com\/horizon\/1828\/getting-fit-to-fight-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Getting fit to fight cancer\" \/>\n<meta property=\"og:description\" content=\"Survival rates for cancer are improving, but it is still the leading cause of death by disease for those over one year of age in the European Union (EU). 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By Helen Massy-Beresford Dealing with cancer in children is hard enough. 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Prescribing unlicensed drugs or the \u2018off-label\u2019 use\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2021\/02\/national-cancer-institute-vbuR2q56EZM-unsplash-scaled.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2021\/02\/national-cancer-institute-vbuR2q56EZM-unsplash-scaled.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2021\/02\/national-cancer-institute-vbuR2q56EZM-unsplash-scaled.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2021\/02\/national-cancer-institute-vbuR2q56EZM-unsplash-scaled.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2021\/02\/national-cancer-institute-vbuR2q56EZM-unsplash-scaled.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2021\/02\/national-cancer-institute-vbuR2q56EZM-unsplash-scaled.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1966,"url":"https:\/\/scienceblog.com\/horizon\/1966\/europes-beating-cancer-plan-and-eu-mission-on-cancer-add-real-momentum-to-tackle-the-entire-disease-pathway\/","url_meta":{"origin":1828,"position":2},"title":"Europe\u2019s Beating Cancer Plan and EU Mission on Cancer add real momentum to tackle the entire disease pathway","author":"Horizon Magazine","date":"February 16, 2022","format":false,"excerpt":"The implementation of Europe\u2019s Beating Cancer Plan and the EU Mission on Cancer will go far beyond research and innovation to develop new solutions and improve the lives of Europeans, says Joanna Drake, Deputy Director-General, DG Research and Innovation (RTD). \u00a0 More Europeans are surviving cancer than ever before, and\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2022\/02\/Feb-3-photo-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2022\/02\/Feb-3-photo-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2022\/02\/Feb-3-photo-1.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":1141,"url":"https:\/\/scienceblog.com\/horizon\/1141\/treating-cancer-is-only-part-of-the-journey-the-overlooked-needs-of-cancer-survivors\/","url_meta":{"origin":1828,"position":3},"title":"\u2018Treating cancer is only part of the journey\u2019: the overlooked needs of cancer survivors","author":"Richard Gray","date":"February 4, 2020","format":false,"excerpt":"As more people live for years and even decades after being diagnosed with cancer, the question of how best to support survivors is a challenge now facing health systems in Europe. More research into survivors\u2019 specific care and support requirements is now needed, say experts. For many people, it is\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"Better cancer treatments means there is a growing number of cancer survivors in Europe and we need to work out how best to support them. Image credit - pxfuel, licensed under CC0","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2020\/02\/cancer-scaled.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2020\/02\/cancer-scaled.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2020\/02\/cancer-scaled.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2020\/02\/cancer-scaled.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2020\/02\/cancer-scaled.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2020\/02\/cancer-scaled.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":971,"url":"https:\/\/scienceblog.com\/horizon\/971\/will-we-ever-cure-cancer\/","url_meta":{"origin":1828,"position":4},"title":"Will we ever cure cancer?","author":"Horizon Magazine","date":"September 18, 2019","format":false,"excerpt":"Cancer is a group of diseases that we may never be able to cure completely, but scientists are optimistic that vaccines, personalised medicine and smart lifestyle choices will help prevent and treat a much greater proportion of cases than currently happens. We asked three cancer experts - Nobel laureate Professor\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"Many of the risk factors to do with cancer are related to lifestyle, so there is concrete action people can take to avoid getting the disease. 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