{"id":671,"date":"2019-02-05T13:44:02","date_gmt":"2019-02-05T13:44:02","guid":{"rendered":"http:\/\/horizon.peachpuff-wolverine-566518.hostingersite.com\/?p=671"},"modified":"2019-02-05T13:44:02","modified_gmt":"2019-02-05T13:44:02","slug":"in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig","status":"publish","type":"post","link":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/","title":{"rendered":"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig"},"content":{"rendered":"

Professor Rolf Bjerkvig, a specialist in brain cancer research,\u00a0tells us why\u00a0guerrilla cells make\u00a0the disease so hard to treat.<\/strong><\/h3>\n
\n
\n
\n

Brain tumours are hard to treat completely with surgery because they leave behind cells that invade the brain. In this video, which covers 72 hours, you can see cells breaking off from a tumour to invade other parts of the brain.<\/p>\n

These cells are guerrilla cells in many ways \u2013 you can\u2019t decipher them from normal cells. My research is that I try to understand why they are invading and how we can target these cells.<\/p>\n

You can\u2019t easily pick out these invasive cells in the human brain, so we grow mini-brains \u2013 organoids \u2013 in the lab. These organoids, with a size of 0.5mm, display the neurons and cellular components you have in a brain.<\/p>\n

Then we take tumour biopsies from patients and barcode them with colour to see different tumour cell populations. We put them next to the mini-brains and then we can study their invasion into the brain.<\/p>\n

What you see in the video is a brain tumour from a patient. You can see different cancer cells with different colours invading into the brain tissue. Brain cancers have lots of different tumour cell types, which makes them complex to treat. Therapies may kill one type of tumour cell but not all.<\/p>\n

\n
\n

\u2018Brain cancers have lots of different types of tumour cells, which makes them complex to treat. Therapies may kill one type of tumour cell but not all.\u2019\u00a0Professor Rolf Bjerkvig, Luxembourg Institute of Health<\/span><\/p>\n<\/blockquote>\n<\/div>\n

On the left side is the micro-brain but you can\u2019t see it because it\u2019s not stained. And with the video we can see the tumour cells migrating into the brain. We can also measure the speed of invasion and this gives us a unique opportunity to characterise the invasive cells and also to find out what kind of mechanism they are using for their migration.<\/p>\n

Around 10 in 100,000 people develop brain tumours. For the most malignant type \u2013 glioblastoma \u2013 patients who are given the best therapy available live about 14-16 months after diagnosis. Brain tumours do not normally spread, like other cancers, but they stay in the brain. It\u2019s therefore regarded as a local disease. The main problem is the location \u2013 the brain is the computer of the human body.<\/p>\n

To get chemotherapeutics into the brain is difficult because the brain is protected by a so-called blood-brain barrier that prevents unwanted chemicals from the blood going into the brain. This barrier also prevents therapeutic substances from entering the brain. The brain thus protects the tumour from the therapy.<\/p>\n

We have a large brain research centre in Norway and Luxembourg. At present we are working to find molecules so we can temporarily open the blood-brain barrier to make a delivery window of therapies into the brain.<\/p>\n

There is a lot of ongoing research on brain cancer but there has been little progress on actually finding new therapies. One problem is that brain tumour research from the European Commission side has been very under-financed. There is a tendency to focus on more common tumour types that affect more people. Brain cancer is regarded as a rare disease. But in this context you are often competing for financing with neurological diseases and many other rare diseases.<\/p>\n

In the private sector, pharma companies focus mostly on the development of blockbuster drugs that can work on millions of people rather than a couple of hundred thousand people. Brain cancer isn\u2019t completely neglected but it is some way down in their portfolio.<\/p>\n

\"Prof.<\/p>\n

Prof. Rolf Bjerkvig\u2019s research group is looking at how to open the blood-brain barrier to allow treatments to reach brain tumours. Image Credit – Kim E. Andreassen, University of Bergen<\/p>\n<\/div>\n

There is at present a strong focus on personalised treatment initiatives. Many of these are based on sequencing the tumour genome, where the aim is to use this information to find the right therapy for the right patient. Unfortunately, transferring the knowledge gained from genetics into effective treatment has mostly been difficult. So can you shortcut this?<\/p>\n

At Luxembourg Institute of Health, we are focusing on a personalised functional profiling (PFP) system where hundreds of microtumors are generated directly from a patient. These are then exposed, in an automated way, to a library of FDA approved drugs. In this way we can identify the most effective drugs that potentially will work. At the same time we do genomic profiling and then we can correlate the drugs to the genomic profile.<\/p>\n

We have seen promising effects using this approach but we need to increase the number of patients and then we can start to make statistical analysis. That\u2019s why we need support for our PFP centre. It should, however be recognised that many of these drugs wouldn\u2019t cross the blood-brain barrier. So in many instances this needs to be combined with the strategies for delivery \u2013 how to deliver this to the brain.<\/p>\n

Prof. Bjerkvig is head of the oncology department at Luxembourg Institute of Health and a professor anatomy and cell biology at the University of Bergen in Norway. He\u00a0led the EU-funded project\u00a0ANGIOTARGETING<\/a>.<\/em><\/strong><\/p>\n

As told to Joanna Roberts. This account has been edited and condensed. The views expressed in the article are those of the interviewee and do not necessarily reflect the position of the European Commission.<\/em><\/strong><\/p>\n

Originally published on Horizon<\/a>.\u00a0<\/em><\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Professor Rolf Bjerkvig, a specialist in brain cancer research,\u00a0tells us why\u00a0guerrilla cells make\u00a0the disease so hard to treat. Brain tumours are hard to treat completely with surgery because they leave behind cells that invade the brain. In this video, which covers 72 hours, you can see cells breaking off from a tumour to invade other … Read more<\/a><\/p>\n","protected":false},"author":309,"featured_media":672,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"generate_page_header":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[10],"tags":[46,94,95,79,24],"class_list":["post-671","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-brain-behavior","tag-brain","tag-cancer","tag-medicine","tag-research","tag-science"],"yoast_head":"\nIn a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig - Horizon Magazine Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig\" \/>\n<meta property=\"og:description\" content=\"Professor Rolf Bjerkvig, a specialist in brain cancer research,\u00a0tells us why\u00a0guerrilla cells make\u00a0the disease so hard to treat. Brain tumours are hard to treat completely with surgery because they leave behind cells that invade the brain. In this video, which covers 72 hours, you can see cells breaking off from a tumour to invade other ... Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/\" \/>\n<meta property=\"og:site_name\" content=\"Horizon Magazine Blog\" \/>\n<meta property=\"article:published_time\" content=\"2019-02-05T13:44:02+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2019\/02\/vlcsnap-2019-02-04-10h27m45s762.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Joanna Roberts\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Joanna Roberts\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/\"},\"author\":{\"name\":\"Joanna Roberts\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#\\\/schema\\\/person\\\/11f7dad77b9a5ed1681c0a736e60548c\"},\"headline\":\"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig\",\"datePublished\":\"2019-02-05T13:44:02+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/\"},\"wordCount\":911,\"publisher\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2019\\\/02\\\/vlcsnap-2019-02-04-10h27m45s762.png\",\"keywords\":[\"brain\",\"cancer\",\"medicine\",\"research\",\"science\"],\"articleSection\":[\"Brain & Behavior\"],\"inLanguage\":\"en-US\",\"copyrightYear\":\"2019\",\"copyrightHolder\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/#organization\"}},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/\",\"url\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/\",\"name\":\"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig - Horizon Magazine Blog\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2019\\\/02\\\/vlcsnap-2019-02-04-10h27m45s762.png\",\"datePublished\":\"2019-02-05T13:44:02+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/#primaryimage\",\"url\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2019\\\/02\\\/vlcsnap-2019-02-04-10h27m45s762.png\",\"contentUrl\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2019\\\/02\\\/vlcsnap-2019-02-04-10h27m45s762.png\",\"width\":1280,\"height\":1024,\"caption\":\"Brain tumours contain many different types of cells, here stained different colours, which makes them complex to treat. Video credit - Wenjing Zhou\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/671\\\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#website\",\"url\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/\",\"name\":\"Horizon Magazine Blog\",\"description\":\"The EU Research & Innovation Magazine\",\"publisher\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#organization\",\"name\":\"Horizon Magazine Blog\",\"url\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2026\\\/04\\\/eu-logo.jpg\",\"contentUrl\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2026\\\/04\\\/eu-logo.jpg\",\"width\":601,\"height\":283,\"caption\":\"Horizon Magazine Blog\"},\"image\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/#\\\/schema\\\/person\\\/11f7dad77b9a5ed1681c0a736e60548c\",\"name\":\"Joanna Roberts\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c205dff9279afd2f58ff92b0ae0d97f3976b628b22a32793d1f02d7ab7b61999?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c205dff9279afd2f58ff92b0ae0d97f3976b628b22a32793d1f02d7ab7b61999?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c205dff9279afd2f58ff92b0ae0d97f3976b628b22a32793d1f02d7ab7b61999?s=96&d=mm&r=g\",\"caption\":\"Joanna Roberts\"},\"url\":\"https:\\\/\\\/scienceblog.com\\\/horizon\\\/author\\\/joannaroberts\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig - Horizon Magazine Blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/","og_locale":"en_US","og_type":"article","og_title":"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig","og_description":"Professor Rolf Bjerkvig, a specialist in brain cancer research,\u00a0tells us why\u00a0guerrilla cells make\u00a0the disease so hard to treat. Brain tumours are hard to treat completely with surgery because they leave behind cells that invade the brain. In this video, which covers 72 hours, you can see cells breaking off from a tumour to invade other ... Read more","og_url":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/","og_site_name":"Horizon Magazine Blog","article_published_time":"2019-02-05T13:44:02+00:00","og_image":[{"width":1280,"height":1024,"url":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2019\/02\/vlcsnap-2019-02-04-10h27m45s762.png","type":"image\/png"}],"author":"Joanna Roberts","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Joanna Roberts","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/#article","isPartOf":{"@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/"},"author":{"name":"Joanna Roberts","@id":"https:\/\/scienceblog.com\/horizon\/#\/schema\/person\/11f7dad77b9a5ed1681c0a736e60548c"},"headline":"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig","datePublished":"2019-02-05T13:44:02+00:00","mainEntityOfPage":{"@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/"},"wordCount":911,"publisher":{"@id":"https:\/\/scienceblog.com\/horizon\/#organization"},"image":{"@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/#primaryimage"},"thumbnailUrl":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2019\/02\/vlcsnap-2019-02-04-10h27m45s762.png","keywords":["brain","cancer","medicine","research","science"],"articleSection":["Brain & Behavior"],"inLanguage":"en-US","copyrightYear":"2019","copyrightHolder":{"@id":"https:\/\/scienceblog.com\/#organization"}},{"@type":"WebPage","@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/","url":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/","name":"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig - Horizon Magazine Blog","isPartOf":{"@id":"https:\/\/scienceblog.com\/horizon\/#website"},"primaryImageOfPage":{"@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/#primaryimage"},"image":{"@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/#primaryimage"},"thumbnailUrl":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2019\/02\/vlcsnap-2019-02-04-10h27m45s762.png","datePublished":"2019-02-05T13:44:02+00:00","breadcrumb":{"@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/#primaryimage","url":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2019\/02\/vlcsnap-2019-02-04-10h27m45s762.png","contentUrl":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2019\/02\/vlcsnap-2019-02-04-10h27m45s762.png","width":1280,"height":1024,"caption":"Brain tumours contain many different types of cells, here stained different colours, which makes them complex to treat. Video credit - Wenjing Zhou"},{"@type":"BreadcrumbList","@id":"https:\/\/scienceblog.com\/horizon\/671\/in-a-picture-hunting-down-guerrilla-tumour-cells-prof-rolf-bjerkvig\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/scienceblog.com\/horizon\/"},{"@type":"ListItem","position":2,"name":"In a picture: Hunting down guerrilla tumour cells \u2013 Prof. Rolf Bjerkvig"}]},{"@type":"WebSite","@id":"https:\/\/scienceblog.com\/horizon\/#website","url":"https:\/\/scienceblog.com\/horizon\/","name":"Horizon Magazine Blog","description":"The EU Research & Innovation Magazine","publisher":{"@id":"https:\/\/scienceblog.com\/horizon\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/scienceblog.com\/horizon\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/scienceblog.com\/horizon\/#organization","name":"Horizon Magazine Blog","url":"https:\/\/scienceblog.com\/horizon\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/scienceblog.com\/horizon\/#\/schema\/logo\/image\/","url":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2026\/04\/eu-logo.jpg","contentUrl":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2026\/04\/eu-logo.jpg","width":601,"height":283,"caption":"Horizon Magazine Blog"},"image":{"@id":"https:\/\/scienceblog.com\/horizon\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/scienceblog.com\/horizon\/#\/schema\/person\/11f7dad77b9a5ed1681c0a736e60548c","name":"Joanna Roberts","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/c205dff9279afd2f58ff92b0ae0d97f3976b628b22a32793d1f02d7ab7b61999?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c205dff9279afd2f58ff92b0ae0d97f3976b628b22a32793d1f02d7ab7b61999?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c205dff9279afd2f58ff92b0ae0d97f3976b628b22a32793d1f02d7ab7b61999?s=96&d=mm&r=g","caption":"Joanna Roberts"},"url":"https:\/\/scienceblog.com\/horizon\/author\/joannaroberts\/"}]}},"jetpack_featured_media_url":"https:\/\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2019\/02\/vlcsnap-2019-02-04-10h27m45s762.png","jetpack_shortlink":"https:\/\/wp.me\/pgtNKV-aP","jetpack_sharing_enabled":true,"jetpack-related-posts":[{"id":2481,"url":"https:\/\/scienceblog.com\/horizon\/2481\/shining-light-on-an-aggressive-brain-cancer\/","url_meta":{"origin":671,"position":0},"title":"Shining light on an aggressive brain cancer","author":"Horizon Magazine","date":"September 6, 2023","format":false,"excerpt":"EU research is uncovering ways to treat a deadly tumour on the rise around the world. By\u00a0\u00a0ANTHONY KING Brain surgeons need steady hands as well as cool heads. Now they\u2019re getting a helping hand from researchers in Europe to fight a fatal type of brain cancer called glioblastoma. A Danish\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/09\/5-scaled.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/09\/5-scaled.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/09\/5-scaled.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/09\/5-scaled.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/09\/5-scaled.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/09\/5-scaled.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2471,"url":"https:\/\/scienceblog.com\/horizon\/2471\/colorectal-cancer-patients-may-benefit-from-breakthrough-eu-research\/","url_meta":{"origin":671,"position":1},"title":"Colorectal cancer patients may benefit from breakthrough EU research","author":"Horizon Magazine","date":"August 24, 2023","format":false,"excerpt":"Scientists in Spain have developed a potentially life-saving strategy against a disease that spreads from the gut to other vital organs. By\u00a0\u00a0ANTHONY KING Cancer of the colon and rectum is a pernicious killer. A colorectal tumour, for example, can be removed completely from a patient but then pop up elsewhere\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/08\/24.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/08\/24.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/08\/24.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/08\/24.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":325,"url":"https:\/\/scienceblog.com\/horizon\/325\/discovery-of-hybrid-cancer-cells-reveals-how-disease-spreads\/","url_meta":{"origin":671,"position":2},"title":"Discovery of hybrid cancer cells reveals how disease spreads","author":"Aisling Irwin","date":"June 18, 2018","format":false,"excerpt":"Scientists studying skin and breast cancer in genetically modified mice have spotted hybrid cancer cells that combine the properties of different cell types, a discovery that could help understand how cancer spreads in the body and provide a new target for treatment. It is the latest insight in a fast-moving\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"Studies show that hybrid cancer cells (in yellow) combine properties of different cells which can make them more invasive.","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/06\/hybrid_cancer_cells_crp.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/06\/hybrid_cancer_cells_crp.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/06\/hybrid_cancer_cells_crp.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/06\/hybrid_cancer_cells_crp.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/06\/hybrid_cancer_cells_crp.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/06\/hybrid_cancer_cells_crp.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2611,"url":"https:\/\/scienceblog.com\/horizon\/2611\/fighting-brain-tumours-with-the-help-of-viruses-and-molecules\/","url_meta":{"origin":671,"position":3},"title":"Fighting brain tumours with the help of viruses and molecules","author":"Horizon Magazine","date":"December 18, 2023","format":false,"excerpt":"By harnessing unusual allies, pioneering cancer treatments could reduce the need for invasive surgery and save lives. By \u00a0Tereza Pultarova Dr Marta Alonso, a Spanish biomedical researcher, developed an interest in paediatric brain tumours during a traineeship in the US state of Texas. Alonso had a chance encounter in 2007\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/12\/18.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/12\/18.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/12\/18.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/12\/18.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/12\/18.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2023\/12\/18.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":387,"url":"https:\/\/scienceblog.com\/horizon\/387\/mini-brains-offer-hope-in-search-for-new-drugs-for-brain-disorders\/","url_meta":{"origin":671,"position":4},"title":"Mini-brains offer hope in search for new drugs for brain disorders","author":"Anthony King","date":"July 30, 2018","format":false,"excerpt":"Miniature brains grown in laboratory dishes could overcome some of the problems testing drugs on animals and help researchers identify new ways to treat very human, and incurable, conditions like Alzheimer's disease and epilepsy. Most new drugs are developed and tested using mice as models. However, with brain disorders such\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"Cerebral organoids allow scientists to test new drugs on human brain tissue in labs.","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/07\/image002_crp.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/07\/image002_crp.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/07\/image002_crp.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/07\/image002_crp.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2018\/07\/image002_crp.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":2834,"url":"https:\/\/scienceblog.com\/horizon\/2834\/3d-printed-living-cells-pave-way-for-tomorrows-medicine-and-cruelty-free-animal-products\/","url_meta":{"origin":671,"position":5},"title":"3D-printed living cells pave way for tomorrow’s medicine and cruelty-free animal products","author":"Horizon Magazine","date":"August 23, 2024","format":false,"excerpt":"EU-funded researchers are expanding the possibilities of 3D printing to create miniature human organs and a variety of products made from living tissue, including food. By Tereza Pultarova 3D printing has come a long way since its early days in the 1980s and is considered an essential tool in many\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/horizon\/category\/health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2024\/08\/23.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2024\/08\/23.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2024\/08\/23.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2024\/08\/23.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2024\/08\/23.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/scienceblog.com\/horizon\/wp-content\/uploads\/sites\/4\/2024\/08\/23.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/posts\/671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/users\/309"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/comments?post=671"}],"version-history":[{"count":0,"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/posts\/671\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/media\/672"}],"wp:attachment":[{"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/media?parent=671"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/categories?post=671"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceblog.com\/horizon\/wp-json\/wp\/v2\/tags?post=671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}