1.0Josh Mitteldorfhttps://scienceblog.com/joshmitteldorfJosh Mitteldorfhttps://scienceblog.com/joshmitteldorf/author/joshmitteldorf/rich600338<blockquote class="wp-embedded-content" data-secret="r8RNXX82rB"><a href="https://scienceblog.com/joshmitteldorf/2023/08/04/cellular-rejuvenation-without-yamanaka/">Cellular Rejuvenation Without Yamanaka</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://scienceblog.com/joshmitteldorf/2023/08/04/cellular-rejuvenation-without-yamanaka/embed/#?secret=r8RNXX82rB" width="600" height="338" title="“Cellular Rejuvenation Without Yamanaka” — Josh Mitteldorf" data-secret="r8RNXX82rB" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://scienceblog.com/joshmitteldorf/wp-includes/js/wp-embed.min.js </script> https://scienceblog.com/joshmitteldorf/wp-content/uploads/sites/2/2023/08/cell-rejuv.png685400The Yamanaka factors (four proteins, abbreviated OSKM) are a treatment that can completely reset any ordinary, functional cell into a pluripotent stem cell, able to regenerate tissues of any type. In the process, the cell loses epigenetic markers of age and reverts to an embryonic state. But differentiated cells are differentiated so they can be ... Read more