{"id":1066,"date":"2021-05-10T02:43:05","date_gmt":"2021-05-10T02:43:05","guid":{"rendered":"https:\/\/joshmitteldorf.peachpuff-wolverine-566518.hostingersite.com\/?p=1066"},"modified":"2022-08-13T14:51:16","modified_gmt":"2022-08-13T14:51:16","slug":"unthinkable-thoughts","status":"publish","type":"post","link":"https:\/\/scienceblog.com\/joshmitteldorf\/2021\/05\/10\/unthinkable-thoughts\/","title":{"rendered":"Unthinkable Thoughts"},"content":{"rendered":"<p><em>This essay is inspired by\u00a0<\/em><a href=\"https:\/\/articles.mercola.com\/sites\/articles\/archive\/2021\/05\/04\/removing-articles-related-to-vitamin-d-c-and-zinc.aspx\" target=\"_blank\" rel=\"noopener\"><em>Dr Mercola\u2019s announcement<\/em><\/a><em>\u00a0last week that (reading between the lines) his life and his family\u2019s have been threatened if he doesn\u2019t remove from his web site a peer-reviewed study demonstrating the benefits of vitamin D and zinc in prevention of the worst COVID outcomes. In the present Orwellian era, where propaganda and deception are ubiquitous, one of the signposts of truth that I have learned to respect is that the most important truths are the most heavily censored.<\/em><\/p>\n<hr \/>\n<p>This is not what I enjoy writing about, but as I find dark thoughts creeping into my consciousness, perhaps it is better to put them on paper with supporting logic and invite my readers to help me clarify the reasoning and, perhaps, to point a way out of the darkness.<\/p>\n<p>Already in January, 2020, two ideas about COVID were emerging. One is that there were people and institutions who seemed to have anticipated the event, and were planning for it for a long time. Gates, Fauci, the World Economic Forum, and Johns Hopkins School of Medicine were among the prescient. (I credit the (now deleted) videos of\u00a0<a href=\"https:\/\/www.bitchute.com\/video\/EwrQonXzO0FG\/\" target=\"_blank\" rel=\"noopener\">Spiro Skouras<\/a>.) Second was the genetic evidence suggesting that <a href=\"https:\/\/scienceblog.com\/joshmitteldorf\/2020\/04\/17\/where-did-covid-19-come-from\/\" target=\"_blank\" rel=\"noopener\">COVID had a laboratory origin<\/a>. Funders of the scientific establishment have lost their bid to\u00a0<a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30418-9\/fulltext\" target=\"_blank\" rel=\"noopener\">ridicule this idea<\/a>, and it has now\u00a0<a href=\"https:\/\/www.npr.org\/2021\/03\/31\/983156340\/theory-that-covid-came-from-a-chinese-lab-takes-on-new-life-in-wake-of-who-repor\" target=\"_blank\" rel=\"noopener\">leaked into the mainstream<\/a>, where it is fused with the classical\u00a0<a href=\"https:\/\/aaww.org\/yellow-peril-scapegoating\/\" target=\"_blank\" rel=\"noopener\">yellow peril<\/a>\u00a0propaganda: \u201cChina did it!\u201d. I\u00a0<a href=\"https:\/\/scienceblog.com\/joshmitteldorf\/2020\/04\/21\/where-did-covid-19-come-from-part-2\/\" target=\"_blank\" rel=\"noopener\">have cited evidence<\/a> that America is likely equally culpable.<\/p>\n<p>The confluence of these two themes suggests the dark logic that I take for my topic today: Those who knew in advance, not only that there would be a pandemic but\u00a0<a href=\"https:\/\/www.centerforhealthsecurity.org\/event201\/\" target=\"_blank\" rel=\"noopener\">that it would be a Coronavirus<\/a>, were actually responsible for engineering this pandemic.<\/p>\n<p>Immediately, I think: How could people capable of such sociopathic enormities be occupying the\u00a0<a href=\"https:\/\/www.google.com\/books\/edition\/Giants\/lpJLDwAAQBAJ?hl=en&amp;gbpv=1&amp;dq=giants&amp;printsec=frontcover\" target=\"_blank\" rel=\"noopener\">most powerful circles of the world\u2019s elite<\/a>? And what would be their motivation? I don\u2019t have answers to these questions, and I will leave speculation to others. But there\u2019s one attractive answer that I find less compelling: that it\u2019s a money-maker for the large and\u00a0<a href=\"https:\/\/experimentalfrontiers.peachpuff-wolverine-566518.hostingersite.com\/2021\/04\/27\/trust-me-im-a-medical-researcher\/\" target=\"_blank\" rel=\"noopener\">criminal pharmaceutical industry<\/a>. The new mRNA vaccines are already the most profitable drugs in history, but I think that shutdown of world economies, <a href=\"https:\/\/unlimitedhangout.com\/2021\/03\/investigative-reports\/tanzanias-late-president-magufuli-science-denier-or-threat-to-empire\/\">assassinations of world leaders<\/a>, deep corruption of science, and full-spectrum control of the mainstream narrative imply a larger power base than can plausibly be commanded by the pharma industry.<\/p>\n<p>Instead, I\u2019ll try to follow the scientific and medical implications of the hypothesis that COVID is a bioweapon.<\/p>\n<p><strong>The Spike Protein<\/strong><\/p>\n<p>The spike protein is the part of the virus structure that interfaces with the host cell. SARS 1 and SARS 2 viruses both have spike proteins that bind to a human cell receptor called ACE-2, common in lung cells but also present in other parts of the body. Binding to the cell\u2019s ACE-2 receptor is like the wolf knocking at the door of Little Red Riding Hood\u2019s grandmother. \u201cHello, grandmama. I\u2019m your granddaughter. Please let me in.\u201d The virus is a wolf wearing a red cape and hood, pretends to be an ACE-2 enzyme molecule seeking entrance to the cell.<\/p>\n<p>In order to enter the cell, the virus must break off from the spike protein and leave it at the doorstep, so to speak. This is an important and difficult step, as it turns out. Unique to the SARS-CoV-2 virus is a trick for making the separation. Just at the edge of the protein is a<a href=\"https:\/\/www.nature.com\/articles\/s41392-020-0184-0\" target=\"_blank\" rel=\"noopener\">\u00a0furin cleavage site<\/a>. Furin is an enzyme that snips protein molecules, and it is common in our bodies, with legitimate metabolic uses. A furin cleavage site is a string of 4 particular amino acids that calls to furin, \u201chey \u2014 come over here. I\u2019m a protein that needs snipping.\u201d<\/p>\n<p>The most compelling evidence for a laboratory origin of COVID is that coronaviruses don\u2019t have furin cleavage sites, and until last year, this trick has never evolved naturally.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large\" src=\"https:\/\/media.springernature.com\/m685\/springer-static\/image\/art%3A10.1038%2Fs41598-020-74101-0\/MediaObjects\/41598_2020_74101_Fig1_HTML.png\" width=\"679\" height=\"685\" \/><\/p>\n<p><strong>How we think about natural disease<\/strong><\/p>\n<p>The classical understanding of a viral or bacterial disease is this: A parasite is an organism that uses the host\u2019s resources for its own reproduction. It is evolved to reproduce efficiently. If it has co-evolved with the host, it may be evolved to spare the host\u2019s health, or even to promote it, because this is the\u00a0<a href=\"https:\/\/www.jstor.org\/stable\/3881531?seq=1\" target=\"_blank\" rel=\"noopener\">optimal long-term strategy<\/a>\u00a0for any predator or parasite. But newly-emerged parasites can do well for awhile even if they disable or kill their hosts, and this is the kind of disease that is most damaging to us. The damage is done because the (young) virus\u2019s strategy is to reproduce rapidly and disperse itself into the environment where it can find new hosts. The virus has no interest in harming the host, and was not evolved to this end, but this is a side-effect of commandeering the body\u2019s resources for its own reproduction.<\/p>\n<p><strong>How engineered diseases can be different<\/strong><\/p>\n<p>A bioweapon virus is designed to cause a certain kind of harm.<\/p>\n<ul>\n<li><em>What kind of harm?\u00a0<\/em>It depends on the projected use for the weapon.<\/li>\n<li><em>Doesn\u2019t the virus have to reproduce?\u00a0<\/em>Probably, for most weapon applications; but a bioweapon is not necessarily designed for rapid reproduction. A bioweapon can be designed as a \u201csleeper\u201d to remain dormant for months or years, or to cause incremental disability over a long period.<\/li>\n<\/ul>\n<p>If COVID had evolved naturally, we would expect that its spike protein would be adapted to mate well with the human ACE-2 receptor. There\u2019s no reason to suspect it being otherwise biologically active. But if COVID is engineered, it may be that the spike protein itself has been designed to make us sick.<\/p>\n<p>One reason this is significant is that the vaccines have all been designed around the spike protein, assuming that the spike protein were metabolically neutral. If the virus had been naturally evolved, this is a reasonable assumption. But if it came from a laboratory (whether it leaked or was deliberately released) the spike protein might actually be the agent of damage. There are several reasons to suspect that this is the case.<\/p>\n<p><strong>The Spike Protein as an Active Pathogen<\/strong><\/p>\n<p>Back in February, 2020,\u00a0<a href=\"https:\/\/www.nature.com\/articles\/s41591-020-0820-9\" target=\"_blank\" rel=\"noopener\">this article<\/a> noted that the spike protein was not perfectly optimized to bind to human ACE-2 and put this forward as a proof that \u201cSARS-CoV-2 is not a purposefully manipulated virus.\u201d But if someone were designing the virus to cause harm, the spike protein would be a convenient locus for the damage vector, so the spike might have been designed with twin purposes in mind, binding and toxicity. The spike protein appears in many copies around the \u201ccrown\u201d of the coronavirus. Since each copy has a furin cleavage site at its base, many spike proteins will break off into the bloodstream. We now have several reports and hypotheses concerning the spike protein as an active agent of damage. The spike protein is suspected of causing blood clots, of inducing long-lasting neurological damage, and of causing infertility. Many anecdotes describe injuries to un-vaccinated people who have been in close proximity to vaccinated, prompting speculation about \u201cshedding\u201d the spike protein.<\/p>\n<blockquote>\n<p style=\"text-align: justify\"><span style=\"color: #362f2d\">\u201cIndividuals with COVID-19 experience a vast number of neurological symptoms, such as headaches, ataxia, impaired consciousness, hallucinations, stroke and cerebral hemorrhage. But autopsy studies have yet to find clear evidence of destructive viral invasion into patients\u2019 brains, pushing researchers to consider alternative explanations of how SARS-CoV-2 causes neurological symptoms\u2026.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify\"><span style=\"color: #362f2d\">If not viral infection, what else could be causing injury to distant organs associated with COVID-19?\u00a0<\/span><span style=\"color: #362f2d\">The most likely culprit that has been identified is the COVID-19 spike protein released from the outer shell of the virus into circulation. Research cited below* has documented that the viral spike protein is able to initiate a cascade of events that triggers damage to distant organs in COVID-19 patients.<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #362f2d\">Worryingly, several studies have found that the spike proteins alone have the capacity to cause widespread injury throughout the body, without any evidence of virus.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify\"><span style=\"color: #362f2d\">What makes this finding so disturbing is that the COVID-19 mRNA vaccines manufactured by Moderna and Pfizer and currently being administered throughout the U.S. program our cells to manufacture this same coronavirus spike protein as a way to trigger our bodies to produce antibodies to the virus.\u201d\u00a0<\/span><a href=\"https:\/\/www.globalresearch.ca\/could-spike-protein-moderna-pfizer-vaccines-cause-blood-clots-brain-inflammation-heart-attacks\/5737069\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #3b4d81\">[Global Research article, Feb 2021<\/span><\/a><span style=\"color: #3b4d81\">]<\/span><\/p>\n<\/blockquote>\n<p>Note: the Astra-Zeneca and J&amp;J vaccines are also based on the spike protein, and cause the spike protein to be created in the vaccinated person.<\/p>\n<p>* \u201cResearch cited below\u201d refers to <a href=\"https:\/\/www.nature.com\/articles\/s41593-020-00771-8\" target=\"_blank\" rel=\"noopener\">this study in Nature<\/a>\u00a0which reports that the spike protein, injected into mice, crosses into the brain, where it causes neurological damage.<\/p>\n<p>Bigger news came just this week from a study in which researchers from California\u2019s Salk Institute collaborated with Chinese virologists. They have found that the bare spike protein without the virus (injected in mice) can cause damaged arteries of the kind that lead to heart disease and strokes in humans. The original paper was published in\u00a0<a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCRESAHA.121.318902\" target=\"_blank\" rel=\"noopener\">Circulation Research<\/a>, and the\u00a0<a href=\"https:\/\/www.salk.edu\/news-release\/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness\/\" target=\"_blank\" rel=\"noopener\">Salk Institute issued a news report<\/a>\u00a0describing the research.<\/p>\n<p>One of the most credible dangers of the spike protein involves fertility. None of the vaccines were tested in pregnant women, and yet many government and other authorities are recommending it as safe for pregnant women. VAERS has reported\u00a0<a href=\"https:\/\/drive.google.com\/file\/d\/13-38eFHZVPLRrT8tb3uznHRH-ahBOOTh\/view?usp=sharing\" target=\"_blank\" rel=\"noopener\">174 miscarriages<\/a>\u00a0to date after COVID vaccination. VAERS is <a href=\"https:\/\/drive.google.com\/file\/d\/1YEe4oe6i94wM7BH-O3tKk3Owl9KYi9Np\/view?usp=sharing\">notoriously underreported<\/a>. I find\u00a0<a href=\"https:\/\/www.visiontimes.com\/2021\/03\/08\/covid-19-vaccine-miscarriage-stillbirth-concerns-for-mothers.html\" target=\"_blank\" rel=\"noopener\">the anecdotes<\/a>\u00a0less concerning than the fact that no one is taking this seriously, and research is being\u00a0<a href=\"https:\/\/blogs.sciencemag.org\/pipeline\/archives\/2021\/05\/04\/spike-protein-behavior\" target=\"_blank\" rel=\"noopener\">actively discouraged in the best-respected science journals<\/a>.<\/p>\n<p>There is a credible mechanism, in that the spike protein is partially homologous to syncytin. Syncytin, in fact, was\u00a0<a href=\"https:\/\/www.nature.com\/articles\/35001608\" target=\"_blank\" rel=\"noopener\">originally a retroviral protein<\/a>, inserted into the mammalian genome many aeons ago, and evolved over the ages to play an essential role in reproduction, binding the placenta to the fetus. An immune response that attacks syncytin might be expected to impose a danger of spontaneous abortion. In any ordinary times, this would be a subject that medical researchers would jump on, with animal tests and field surveys to assess the danger. But these are no ordinary times, and the risk is being <a href=\"https:\/\/www.mdpi.com\/2079-7737\/10\/3\/238\" target=\"_blank\" rel=\"noopener\">dismissed on theoretical grounds<\/a>\u00a0without investigation. This is especially suspicious in the context of history: a Gates Foundation\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12346214\/\" target=\"_blank\" rel=\"noopener\">vaccination program in 1995<\/a> was allegedly promoted to young women, causing infertility. (Yes, I know there are many fact-checkers eager to \u201cdebunk\u201d this story, but I don\u2019t find them convincing, and some of these <a href=\"https:\/\/www.politifact.com\/who-pays-for-politifact\/\" target=\"_blank\" rel=\"noopener\">fact-checkers are compromised by Gates funding<\/a>.)<\/p>\n<p>Even doing what the spike protein is supposed to do &#8212; tying up ACE2 &#8212; can be a <a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCRESAHA.121.318902\">problem for our lungs and arteries<\/a>, which are <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2020.00317\/\">routinely protected by ACE2<\/a>.<\/p>\n<p>The most dangerous possibility, suspected but not verified, is that the spike protein causes a prion cascade. Prions are paradoxical pathogens, in that they are misfolded proteins that cause misfolded proteins. Their evolutionary etiology is utterly mysterious, so much so that it took <a href=\"https:\/\/www.nobelprize.org\/prizes\/medicine\/1997\/summary\/\" target=\"_blank\" rel=\"noopener\">Stanley Prusiner<\/a>\u00a0a decade after describing the\u00a0<a href=\"https:\/\/science.sciencemag.org\/content\/218\/4579\/1309.abstract\" target=\"_blank\" rel=\"noopener\">biology of prions<\/a> before the scientific community would take prion biochemistry seriously. But prions make <a href=\"https:\/\/www.domesticpreparedness.com\/preparedness\/bioterrorism-in-a-technologically-advanced-world\/\" target=\"_blank\" rel=\"noopener\">potent bioweapons<\/a>, which laboratories can design outside of natural evolutionary dynamics. The possibility of prion-like structures in the spike protein was\u00a0<a href=\"http:\/\/hmi-us.com\/publications\/sars-cov-2-prion-like-domains-in-spike-proteins-enable-higher-affinity-to-ace2.html\" target=\"_blank\" rel=\"noopener\">noted very early in the pandemic<\/a>\u00a0based on a computational study.\u00a0<a href=\"https:\/\/winepressnews.com\/2021\/04\/24\/study-shows-covid-vaccines-could-lead-to-prion-disease\/\" target=\"_blank\" rel=\"noopener\">This recent review<\/a>\u00a0combines theoretical, laboratory, and observational evidence to make a case for caution. Once again, I find it disturbing that this possibility is being\u00a0<a href=\"https:\/\/sciencebasedmedicine.org\/can-mrna-based-covid-19-vaccines-cause-prion-disease\/\" target=\"_blank\" rel=\"noopener\">dismissed on theoretical grounds<\/a>\u00a0rather than investigated in the lab and the field.<\/p>\n<p><strong>Where did the idea come from\u00a0<\/strong>that all vaccines are automatically safe? Why do so many journalists dismiss the suggestion that vaccines should be placebo-tested individually, like all other drugs? Why has it become routine to ridicule and denigrate scientists who ask questions about vaccine safety as politically-motivated luddites, or \u201canti-vaxxers\u201d? How did we get to a situation where the \u201cprecautionary principle\u201d means pressuring young people who are at almost no risk for serious COVID to accept a vaccine which has not been fully tested or approved? I don\u2019t have answers, but I do know who benefits from this culture.<\/p>\n<p>Putting together all the evidence<\/p>\n<ul>\n<li>Knowledge beforehand<\/li>\n<li>Suppression of treatments and cures<\/li>\n<li>Toxicity of the spike protein which, if it had been made by nature, should have been benign<\/li>\n<li>Inclusion of the toxic spike protein in the vaccines that are supposed to protect us<\/li>\n<li>Heavy promotion of\u00a0 these scantily-tested vaccines and<\/li>\n<li>Censorship of scientists and doctors who question the vaccines\u2019 safety<\/li>\n<\/ul>\n<p>\u2026 putting together all this evidence, it is difficult to escape the inference that powerful people and organizations have engineered this pandemic with deadly intent.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This essay is inspired by\u00a0Dr Mercola\u2019s announcement\u00a0last week that (reading between the lines) his life and his family\u2019s have been threatened if he doesn\u2019t remove from his web site a peer-reviewed study demonstrating the benefits of vitamin D and zinc in prevention of the worst COVID outcomes. In the present Orwellian era, where propaganda and &#8230; <a title=\"Unthinkable Thoughts\" class=\"read-more\" href=\"https:\/\/scienceblog.com\/joshmitteldorf\/2021\/05\/10\/unthinkable-thoughts\/\" aria-label=\"Read more about Unthinkable Thoughts\">Read more<\/a><\/p>\n","protected":false},"author":65,"featured_media":1067,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[1],"tags":[],"class_list":["post-1066","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Unthinkable Thoughts - Josh Mitteldorf<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/scienceblog.com\/joshmitteldorf\/2021\/05\/10\/unthinkable-thoughts\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Unthinkable Thoughts\" \/>\n<meta property=\"og:description\" content=\"This essay is inspired by\u00a0Dr Mercola\u2019s announcement\u00a0last week that (reading between the lines) his life and his family\u2019s have been threatened if he doesn\u2019t remove from his web site a peer-reviewed study demonstrating the benefits of vitamin D and zinc in prevention of the worst COVID outcomes. In the present Orwellian era, where propaganda and ... Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/scienceblog.com\/joshmitteldorf\/2021\/05\/10\/unthinkable-thoughts\/\" \/>\n<meta property=\"og:site_name\" content=\"Josh Mitteldorf\" \/>\n<meta property=\"article:published_time\" content=\"2021-05-10T02:43:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-08-13T14:51:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/scienceblog.com\/joshmitteldorf\/wp-content\/uploads\/sites\/2\/2021\/05\/spike-protein.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"320\" \/>\n\t<meta property=\"og:image:height\" content=\"449\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Josh Mitteldorf\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Josh Mitteldorf\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2021\\\/05\\\/10\\\/unthinkable-thoughts\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2021\\\/05\\\/10\\\/unthinkable-thoughts\\\/\"},\"author\":{\"name\":\"Josh Mitteldorf\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/#\\\/schema\\\/person\\\/214c5d1dad9f15c48f03128d5cfccdb1\"},\"headline\":\"Unthinkable Thoughts\",\"datePublished\":\"2021-05-10T02:43:05+00:00\",\"dateModified\":\"2022-08-13T14:51:16+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2021\\\/05\\\/10\\\/unthinkable-thoughts\\\/\"},\"wordCount\":2101,\"commentCount\":172,\"publisher\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2021\\\/05\\\/10\\\/unthinkable-thoughts\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/wp-content\\\/uploads\\\/sites\\\/2\\\/2021\\\/05\\\/spike-protein.jpg\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2021\\\/05\\\/10\\\/unthinkable-thoughts\\\/#respond\"]}],\"copyrightYear\":\"2021\",\"copyrightHolder\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/#organization\"}},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2021\\\/05\\\/10\\\/unthinkable-thoughts\\\/\",\"url\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2021\\\/05\\\/10\\\/unthinkable-thoughts\\\/\",\"name\":\"Unthinkable Thoughts - 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The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. It may be that therapies to slow the progress of aging need not repair or regenerate anything, but only need to interfere with an existing program of self-destruction. Mitteldorf has taught a weekly yoga class for thirty years. He is an advocate for vigorous self care, including exercise, meditation and caloric restriction. After earning a PhD in astrophysicist, Mitteldorf moved to evolutionary biology as a primary field in 1996. He has taught at Harvard, Berkeley, Bryn Mawr, LaSalle and Temple University. He is presently affiliated with MIT as a visiting scholar. In private life, Mitteldorf is an advocate for election integrity as well as public health. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. His two daughters are among the first children adopted from China in the mid-1980s. Much to the surprise of evolutionary biologists, genetic experiments indicate that aging has been selected as an adaptation for its own sake. This poses a conundrum: the impact of aging on individual fitness is wholly negative, so aging must be regarded as a kind of evolutionary altruism. Unlike other forms of evolutionary altruism, aging offers benefits to the community that are weak, and not well focussed on near kin of the altruist. This makes the mechanism challenging to understand and to model. more at http:\\\/\\\/mathforum.org\\\/~josh\",\"sameAs\":[\"http:\\\/\\\/AgingAdvice.org\"],\"url\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/author\\\/joshmitteldorf\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Unthinkable Thoughts - Josh Mitteldorf","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/scienceblog.com\/joshmitteldorf\/2021\/05\/10\/unthinkable-thoughts\/","og_locale":"en_US","og_type":"article","og_title":"Unthinkable Thoughts","og_description":"This essay is inspired by\u00a0Dr Mercola\u2019s announcement\u00a0last week that (reading between the lines) his life and his family\u2019s have been threatened if he doesn\u2019t remove from his web site a peer-reviewed study demonstrating the benefits of vitamin D and zinc in prevention of the worst COVID outcomes. 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The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. It may be that therapies to slow the progress of aging need not repair or regenerate anything, but only need to interfere with an existing program of self-destruction. Mitteldorf has taught a weekly yoga class for thirty years. He is an advocate for vigorous self care, including exercise, meditation and caloric restriction. After earning a PhD in astrophysicist, Mitteldorf moved to evolutionary biology as a primary field in 1996. He has taught at Harvard, Berkeley, Bryn Mawr, LaSalle and Temple University. He is presently affiliated with MIT as a visiting scholar. In private life, Mitteldorf is an advocate for election integrity as well as public health. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. His two daughters are among the first children adopted from China in the mid-1980s. Much to the surprise of evolutionary biologists, genetic experiments indicate that aging has been selected as an adaptation for its own sake. This poses a conundrum: the impact of aging on individual fitness is wholly negative, so aging must be regarded as a kind of evolutionary altruism. Unlike other forms of evolutionary altruism, aging offers benefits to the community that are weak, and not well focussed on near kin of the altruist. 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