{"id":399,"date":"2015-07-08T21:22:08","date_gmt":"2015-07-08T21:22:08","guid":{"rendered":"http:\/\/joshmitteldorf.peachpuff-wolverine-566518.hostingersite.com\/?p=399"},"modified":"2015-08-01T14:12:46","modified_gmt":"2015-08-01T14:12:46","slug":"fasting-mimicking-diet-a-disclaimer","status":"publish","type":"post","link":"https:\/\/scienceblog.com\/joshmitteldorf\/2015\/07\/08\/fasting-mimicking-diet-a-disclaimer\/","title":{"rendered":"Fasting-Mimicking Diet &#8211; A Disclaimer"},"content":{"rendered":"<p>Last week, I suggested a do-it-yourself version of Dr Longo&#8217;s FMD diet, and offered sample recipes. I want to clarify that this version was not authorized by Dr Longo or his associates at USC. In fact, they have a large team with expertise in different aspects of health, nutrition and aging, and they have developed a specific package of prepared foods and micronutrients, intended to be administered under a doctor\u2019s supervision.<\/p>\n<p>The package will soon be available as a kit from <a href=\"http:\/\/l-nutra.com\" target=\"_blank\">L-Nutra Corp,<\/a> marketed under the brand <a href=\"http:\/\/l-nutra.com\/index.php\/products\/prolon\" target=\"_blank\">ProLon<\/a>. \u00a0This\u00a0specific diet has been tested in a clinical trial, and the results reported in a <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1550413115002247\" target=\"_blank\">research article<\/a>\u00a0last month.<\/p>\n<p>I designed the recipes on a spreadsheet, and adjusted quantities to recreate the calorie content and the proportions of macronutrients (protein, carbohydrate, and oils) closely matching the FMD. But I know nothing about the actual ingredients in the Pro-Lon package, or the supplements they contain. The ingredients have not yet been announced, and my recipes haven&#8217;t been tested in a clinical trial.<\/p>\n<p>I am enthusiastic about the FMD idea, and I am trying it myself this week. I certainly encourage you to do the same, and I believe that five days of light vegan meals with limited protein and a high proportion of fat is likely to be safe and healthy. This is my recommendation, and not endorsed by Dr Longo.<\/p>\n<p><a href=\"http:\/\/AgingAdvice.org\/FMD-Recipes.html\" target=\"_blank\">Link to list of recipes<\/a>, created with data from <a href=\"http:\/\/ndb.nal.usda.gov\/\/\" target=\"_blank\">USDA nutritional database<\/a>, in cooperation with Enid Kassner.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Last week, I suggested a do-it-yourself version of Dr Longo&#8217;s FMD diet, and offered sample recipes. I want to clarify that this version was not authorized by Dr Longo or his associates at USC. In fact, they have a large team with expertise in different aspects of health, nutrition and aging, and they have developed &#8230; <a title=\"Fasting-Mimicking Diet &#8211; A Disclaimer\" class=\"read-more\" href=\"https:\/\/scienceblog.com\/joshmitteldorf\/2015\/07\/08\/fasting-mimicking-diet-a-disclaimer\/\" aria-label=\"Read more about Fasting-Mimicking Diet &#8211; A Disclaimer\">Read more<\/a><\/p>\n","protected":false},"author":65,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-399","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Fasting-Mimicking Diet - A Disclaimer - Josh Mitteldorf<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/scienceblog.com\/joshmitteldorf\/2015\/07\/08\/fasting-mimicking-diet-a-disclaimer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fasting-Mimicking Diet - A Disclaimer\" \/>\n<meta property=\"og:description\" content=\"Last week, I suggested a do-it-yourself version of Dr Longo&#8217;s FMD diet, and offered sample recipes. I want to clarify that this version was not authorized by Dr Longo or his associates at USC. In fact, they have a large team with expertise in different aspects of health, nutrition and aging, and they have developed ... Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/scienceblog.com\/joshmitteldorf\/2015\/07\/08\/fasting-mimicking-diet-a-disclaimer\/\" \/>\n<meta property=\"og:site_name\" content=\"Josh Mitteldorf\" \/>\n<meta property=\"article:published_time\" content=\"2015-07-08T21:22:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2015-08-01T14:12:46+00:00\" \/>\n<meta name=\"author\" content=\"Josh Mitteldorf\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Josh Mitteldorf\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2015\\\/07\\\/08\\\/fasting-mimicking-diet-a-disclaimer\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/2015\\\/07\\\/08\\\/fasting-mimicking-diet-a-disclaimer\\\/\"},\"author\":{\"name\":\"Josh Mitteldorf\",\"@id\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/#\\\/schema\\\/person\\\/214c5d1dad9f15c48f03128d5cfccdb1\"},\"headline\":\"Fasting-Mimicking Diet &#8211; 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The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. It may be that therapies to slow the progress of aging need not repair or regenerate anything, but only need to interfere with an existing program of self-destruction. Mitteldorf has taught a weekly yoga class for thirty years. He is an advocate for vigorous self care, including exercise, meditation and caloric restriction. After earning a PhD in astrophysicist, Mitteldorf moved to evolutionary biology as a primary field in 1996. He has taught at Harvard, Berkeley, Bryn Mawr, LaSalle and Temple University. He is presently affiliated with MIT as a visiting scholar. In private life, Mitteldorf is an advocate for election integrity as well as public health. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. His two daughters are among the first children adopted from China in the mid-1980s. Much to the surprise of evolutionary biologists, genetic experiments indicate that aging has been selected as an adaptation for its own sake. This poses a conundrum: the impact of aging on individual fitness is wholly negative, so aging must be regarded as a kind of evolutionary altruism. Unlike other forms of evolutionary altruism, aging offers benefits to the community that are weak, and not well focussed on near kin of the altruist. This makes the mechanism challenging to understand and to model. more at http:\\\/\\\/mathforum.org\\\/~josh\",\"sameAs\":[\"http:\\\/\\\/AgingAdvice.org\"],\"url\":\"https:\\\/\\\/scienceblog.com\\\/joshmitteldorf\\\/author\\\/joshmitteldorf\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Fasting-Mimicking Diet - A Disclaimer - Josh Mitteldorf","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/scienceblog.com\/joshmitteldorf\/2015\/07\/08\/fasting-mimicking-diet-a-disclaimer\/","og_locale":"en_US","og_type":"article","og_title":"Fasting-Mimicking Diet - A Disclaimer","og_description":"Last week, I suggested a do-it-yourself version of Dr Longo&#8217;s FMD diet, and offered sample recipes. I want to clarify that this version was not authorized by Dr Longo or his associates at USC. 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The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. It may be that therapies to slow the progress of aging need not repair or regenerate anything, but only need to interfere with an existing program of self-destruction. Mitteldorf has taught a weekly yoga class for thirty years. He is an advocate for vigorous self care, including exercise, meditation and caloric restriction. After earning a PhD in astrophysicist, Mitteldorf moved to evolutionary biology as a primary field in 1996. He has taught at Harvard, Berkeley, Bryn Mawr, LaSalle and Temple University. He is presently affiliated with MIT as a visiting scholar. In private life, Mitteldorf is an advocate for election integrity as well as public health. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. His two daughters are among the first children adopted from China in the mid-1980s. Much to the surprise of evolutionary biologists, genetic experiments indicate that aging has been selected as an adaptation for its own sake. This poses a conundrum: the impact of aging on individual fitness is wholly negative, so aging must be regarded as a kind of evolutionary altruism. Unlike other forms of evolutionary altruism, aging offers benefits to the community that are weak, and not well focussed on near kin of the altruist. 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