Schmoozing good for the brain

Michigan researchers say they’ve found that shooting the bull with friends has measurable benefits for the brain, keeping it sharp in later life. “Most advice for preserving and enhancing mental function emphasizes intellectual activities such as reading, doing crossword puzzles, and learning how to use a computer,” says the lead researcher. “But my research suggests that just getting together and chatting with friends and family may also be effective.”

‘Heartbeats’ may keep galaxies churning

Until now, astronomers haven’t been able to offer a full explanation for why the Milky Way and other galaxies produce new stars at a relative snail’s pace. While they have known for decades that high turbulence keeps huge clouds of hydrogen gas from condensing into stars, they haven’t identified all the causes of the galactic perturbations. In a coming report researchers in San Diego say they have discovered that a well-known, but overlooked source of heating?regular outbursts of ultraviolet radiation from clusters of very large, bright stars?may play a significant role in keeping the Milky Way’s gas continually stirred up.

New drug could help target cancer cells with deadly accuracy

Researchers in Britain have developed a drug they say could revolutionize the effectiveness of radiation on cancer. Radiotherapy is used to destroy cancer cells by zapping their DNA, thus disrupting their ability to function and reproduce. But like other cells in the body, cancer cells have a sort of DNA repair kit that can minimize these effects. The new drug disables the DNA repair process and allows radiotherapy to target tumors with “deadly accuracy.”

Common diabetes drug successfully used to treat pituitary tumor

Using a common diabetes drug, researchers in Los Angeles have successfully treated pituitary tumors that cause a potentially life-threatening condition known as Cushing’s syndrome. The most common type of Cushing’s syndrome is caused by prolonged high-level exposure of a hormone called ACTH (adrenocorticotropin), which is secreted in excess by tumors of the pituitary gland, situated at the base of the brain and, which controls growth, metabolism and reproduction. Although the disorder is rare, it affects more women than men by a ratio of 5:1. Symptoms include weight gain with rounding of the face; increased fat in the neck; thinning skin; excess hair growth on the face neck, chest abdomen and thighs; muscle weakness and bone loss (osteoporosis); high blood sugar; diabetes; and high blood pressure.

Another job discovered for a master metabolic off-switch

Researchers have discovered that an important cellular “off-switch” that desensitizes receptors on the cell surface also regulates a second deactivation mechanism that had not been suspected before. Their finding that the off-switch, known as beta-arrestin, operates in two distinct ways may hint at a broader set of regulatory roles for the molecule.

Study: Coils cut death, disability from brain aneurysms

Brain aneurysms, in which an artery wall balloons out abnormally, can lead to death or disability. Inserting small metal coils into burst aneurysms can decrease by 25 percent the risk of patient death and disability during the first year after the procedure, according to preliminary results of a long-term study published in the The Lancet. The coils are like “miniature slinkies that are folded gently into the aneurysm like a ball of yarn one by one to stop the bleeding,” said one of the researchers, noting that the procedure also can be used to prevent aneurysms from bursting. “With coiling, we can either help fix the damage or prevent it from occurring.” Surgical clipping is currently the most common method of treating brain aneurysms.

Drug significantly improves pain in fibromyalgia patients

A drug called pregabalin has been shown to be an effective and safe treatment for pain in patients with fibromyalgia, according to study data being presented at the annual meeting of the American College of Rheumatology. The drug, Pregabalin, also was shown to improve sleep and fatigue levels, the data demonstrate. Fibromyalgia syndrome (FMS) is a chronic disorder characterized by widespread musculoskeletal pain that is frequently associated with fatigue and sleep disturbances. It is estimated to affect two percent of the population, or 5.6 million Americans, and occurs most frequently in women.

Exercise, talk therapy may help relieve Gulf War veterans’ illness

Regular exercise and a form of group talk therapy can alleviate some symptoms commonly associated with Gulf War veterans’ illnesses, according to newly released results of a study involving veterans who report such symptoms. Fatigue, distress, mental health, and mental ability all improved after three months of low-impact exercise, weekly group sessions of cognitive behavioral therapy (CBT), or both together. The gains were significantly greater than those made by veterans who were given usual care. Physical function improved more in those who had CBT than in those who didn’t.

Brain study of back pain sufferers yields intriguing results

Patients with lower back pain that can’t be traced to a specific physical cause may have abnormal pain-processing pathways in their brains, according to a new study led by Michigan researchers. The effect, which as yet has no explanation, is similar to an altered pain perception effect in fibromyalgia patients recently reported by the same research team.

Scientists Boost Tally at Uranus

A new moon of the planet Uranus has been discovered and confirmed by a team of astronomers at NASA’s Jet Propulsion Laboratory. This most-recently discovered natural satellite, named S/2001 U 1, brings the total number of confirmed uranian moons to 21. The new kid on the block — and five others like it — have very irregular, eccentric orbits that don’t share the same orbital plane as the larger moons of Uranus. Ranging in size from 10 to 20 kilometers, these moons are thought to be remnants of ancient collisions that occurred at the early stage of planetary formation.

Study Identifies Gene That Prevents Nerve Cell Death

Many neurological diseases occur when specific groups of neurons die because of nerve damage, toxins, inflammation, or other factors. A new study suggests that activity of a single gene can stop neurons from dying regardless of what triggers this process. The findings could lead to new ways of treating neurodegenerative diseases.