{"id":243,"date":"2025-08-12T08:07:30","date_gmt":"2025-08-12T15:07:30","guid":{"rendered":"https:\/\/scienceblog.com\/sciencechina\/?p=243"},"modified":"2025-08-12T08:07:30","modified_gmt":"2025-08-12T15:07:30","slug":"china-faces-alzheimer-surge-while-racing-to-improve-care","status":"publish","type":"post","link":"https:\/\/scienceblog.com\/sciencechina\/2025\/08\/12\/china-faces-alzheimer-surge-while-racing-to-improve-care\/","title":{"rendered":"China Faces Alzheimer Surge While Racing to Improve Care"},"content":{"rendered":"<p>China is confronting an unprecedented Alzheimer&#8217;s disease challenge, with nearly 17 million people now living with Alzheimer&#8217;s and related dementias, almost one quarter of the global total. The newly released 2025 China Alzheimer Report, published in <em>General Psychiatry<\/em>, reveals sharp increases in prevalence and mortality since 1990 and outlines how new diagnostics, treatments, and public health policies are reshaping the nation&#8217;s response.<\/p>\n<h2>A Rapidly Growing Burden<\/h2>\n<p>The report, produced by researchers from Shanghai Jiao Tong University and partner institutions, draws on the Global Burden of Disease study and national health data. It shows that Alzheimer&#8217;s prevalence in China rose by more than 240% since 1990, reaching 16.99 million cases in 2021. Women are disproportionately affected, with rates nearly twice those of men. That year, 2.91 million new cases were diagnosed and almost half a million deaths were attributed to Alzheimer&#8217;s.<\/p>\n<p>Eastern, southwestern, and northeastern provinces such as Shanghai, Sichuan, Liaoning, Jiangsu, and Chongqing carry the heaviest load. Overall, China accounts for nearly 30% of global cases, deaths, and disability-adjusted life years (DALYs) from Alzheimer&#8217;s.<\/p>\n<h2>How China Diagnoses Alzheimer&#8217;s<\/h2>\n<p>Standard tools such as magnetic resonance imaging (MRI) and computed tomography (CT) remain central for detecting brain atrophy. Positron emission tomography (PET) is gaining ground for early detection, although high costs and limited access hinder its use. Neuropsychological assessments, fluid biomarkers from cerebrospinal fluid and blood, and even emerging urine-based tests are expanding diagnostic capabilities.<\/p>\n<p>Recent years have also seen the rise of digital screening tools and computer-assisted memory testing. Domestic platforms like CatCog and CoCoSc are being refined for older Chinese adults, alongside international systems such as Cogstate.<\/p>\n<h2>New and Emerging Treatments<\/h2>\n<p>Treatment in China is moving beyond symptomatic drugs like donepezil and memantine toward disease-modifying therapies (DMTs). Notable developments include:<\/p>\n<ul>\n<li><strong>Lecanemab<\/strong>: Approved in China in 2024, this anti-amyloid antibody slows cognitive decline by about 27% in trials. Over 2,000 patients have received it so far.<\/li>\n<li><strong>Donanemab<\/strong>: Gained approval in December 2024 after Phase III data showed a 35% reduction in cognitive decline rates.<\/li>\n<li><strong>SHR-1707<\/strong>: The first domestically developed anti-amyloid antibody, now in Phase II trials.<\/li>\n<li><strong>Neuromodulation therapies<\/strong>: Techniques like transcranial magnetic stimulation and near-infrared light therapy are showing promise for cognitive improvement.<\/li>\n<li><strong>Traditional Chinese medicine<\/strong>: Acupuncture and herbal formulations remain active areas of clinical research.<\/li>\n<\/ul>\n<p>Other innovative avenues include lymphatic-venous anastomosis surgery to enhance brain waste clearance and intranasal delivery of stem cell-derived exosomes, which early studies suggest may improve memory scores without major side effects.<\/p>\n<h2>Prevention, Policy, and Care Infrastructure<\/h2>\n<p>Government-backed initiatives such as the Healthy China 2030 Plan and the 2023\u20132025 Alzheimer&#8217;s prevention campaign are driving early screening and community-based care. The number of specialized memory clinics reached 273 by 2022, with public awareness rising sharply, 80% of patients and families now recognize early symptoms.<\/p>\n<p>Long-term care insurance pilots have expanded to 49 cities, though coverage for dementia remains uneven. Cities like Qingdao and Shanghai have introduced dementia care units and in-home support, easing both the financial and emotional burden on families.<\/p>\n<h2>Global Significance<\/h2>\n<p>China&#8217;s Alzheimer&#8217;s epidemic is not just a national challenge. With nearly one third of the global disease burden, advancements in China&#8217;s diagnostics, drug development, and public health models will influence care strategies worldwide. The 2025 report underscores both the urgency of the crisis and the momentum building in scientific, medical, and policy responses.<\/p>\n<blockquote><p>&#8220;Our findings provide a comprehensive update on AD in China, including the latest diagnostic and treatment advancements, clinical outcomes, and an assessment of public health resources,&#8221; said Dr. Wang, corresponding author of the report.<\/p><\/blockquote>\n<h3>Journal and Citation<\/h3>\n<p><strong>Journal:<\/strong> <em>General Psychiatry<\/em><br \/>\n<strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1136\/gpsych-2024-102020\" target=\"_blank\" rel=\"noopener\">10.1136\/gpsych-2024-102020<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>China is confronting an unprecedented Alzheimer&#8217;s disease challenge, with nearly 17 million people now living with Alzheimer&#8217;s and related dementias, almost one quarter of the global total. The newly released 2025 China Alzheimer Report, published in General Psychiatry, reveals sharp increases in prevalence and mortality since 1990 and outlines how new diagnostics, treatments, and public &#8230; <a title=\"China Faces Alzheimer Surge While Racing to Improve Care\" class=\"read-more\" href=\"https:\/\/scienceblog.com\/sciencechina\/2025\/08\/12\/china-faces-alzheimer-surge-while-racing-to-improve-care\/\" aria-label=\"Read more about China Faces Alzheimer Surge While Racing to Improve Care\">Read more<\/a><\/p>\n","protected":false},"author":1299,"featured_media":244,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[8,10],"tags":[],"class_list":["post-243","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-brain-behavior","category-society","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>China Faces Alzheimer Surge While Racing to Improve Care - SciChi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/scienceblog.com\/sciencechina\/2025\/08\/12\/china-faces-alzheimer-surge-while-racing-to-improve-care\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"China Faces Alzheimer Surge While Racing to Improve Care\" \/>\n<meta property=\"og:description\" content=\"China is confronting an unprecedented Alzheimer&#8217;s disease challenge, with nearly 17 million people now living with Alzheimer&#8217;s and related dementias, almost one quarter of the global total. 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Inside a research lab in China, nine aged rhesus monkeys sat near speakers emitting 40-hertz tones for an\u2026","rel":"","context":"In &quot;Brain &amp; Behavior&quot;","block_context":{"text":"Brain &amp; Behavior","link":"https:\/\/scienceblog.com\/sciencechina\/category\/brain-behavior\/"},"img":{"alt_text":"monkey looking thoughtful","src":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2026\/01\/pexels-alexasfotos-11171325.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2026\/01\/pexels-alexasfotos-11171325.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2026\/01\/pexels-alexasfotos-11171325.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2026\/01\/pexels-alexasfotos-11171325.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":216,"url":"https:\/\/scienceblog.com\/sciencechina\/2025\/07\/09\/back-and-chest-acne-needs-different-treatment-than-face\/","url_meta":{"origin":243,"position":1},"title":"Back and Chest Acne Needs Different Treatment Than Face","author":"ScienceBlog.com","date":"July 9, 2025","format":false,"excerpt":"Nearly half of adults with facial acne also develop breakouts on their chest and back, yet most treatments ignore crucial differences between these body regions. 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The comprehensive analysis, published in the Journal of Dermatologic\u2026","rel":"","context":"In &quot;Health&quot;","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/sciencechina\/category\/health\/"},"img":{"alt_text":"a man's chest and abdomen","src":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/man-1895017_1280.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/man-1895017_1280.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/man-1895017_1280.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/man-1895017_1280.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":222,"url":"https:\/\/scienceblog.com\/sciencechina\/2025\/07\/29\/a-new-vision-of-china-from-space-39-years-in-the-making\/","url_meta":{"origin":243,"position":2},"title":"A New Vision of China from Space, 39 Years in the Making","author":"SciChi","date":"July 29, 2025","format":false,"excerpt":"Chinese researchers have unveiled a powerful new tool for Earth observation: a 30-meter resolution Landsat composite data cube covering every year from 1985 to 2023. The seamless dataset, described in the Journal of Remote Sensing, offers the first annual \u201cLeaf-On\u201d season satellite imagery for all of China. By solving long-standing\u2026","rel":"","context":"In &quot;Environment&quot;","block_context":{"text":"Environment","link":"https:\/\/scienceblog.com\/sciencechina\/category\/environment\/"},"img":{"alt_text":"Fig. 3. The system comprises 91 tiles, each measuring 4\u00b0 \u00d7 4\u00b0. 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Scientists have discovered that Neural EGFL-like 2 (NELL2) plays a crucial role in maintaining bone health\u2014potentially opening the\u2026","rel":"","context":"In &quot;Health&quot;","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/sciencechina\/category\/health\/"},"img":{"alt_text":"Osteoporosis is a disease of bone where there is reduced bone mineral density (R), increasing the likelihood of fractures.","src":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/05\/1600px-Osteoporosis_in_Bones.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/05\/1600px-Osteoporosis_in_Bones.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/05\/1600px-Osteoporosis_in_Bones.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/05\/1600px-Osteoporosis_in_Bones.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":286,"url":"https:\/\/scienceblog.com\/sciencechina\/2025\/11\/14\/ancient-scar-in-southern-china-reveals-earths-largest-modern-crater\/","url_meta":{"origin":243,"position":4},"title":"Ancient Scar In Southern China Reveals Earth\u2019s Largest Modern Crater","author":"SciChi","date":"November 14, 2025","format":false,"excerpt":"A gentle hillside in southern China hides the vast wound of an ancient collision, reminding us how suddenly the sky can rearrange the Earth. In a new study published in Matter and Radiation at Extremes, researchers from Shanghai and Guangzhou confirm that the Jinlin crater in Guangdong Province is the\u2026","rel":"","context":"In &quot;Environment&quot;","block_context":{"text":"Environment","link":"https:\/\/scienceblog.com\/sciencechina\/category\/environment\/"},"img":{"alt_text":"A panoramic aerial drone image of the Jinlin crater with the approximate location of the crater rim labeled, with an insert of the crater floor, which shows a mix of granite weathered soil and granite fragments. The yellow ruler is 20 centimeters long.","src":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/11\/jinlin-crater.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/11\/jinlin-crater.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/11\/jinlin-crater.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/11\/jinlin-crater.jpeg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":219,"url":"https:\/\/scienceblog.com\/sciencechina\/2025\/07\/25\/ancient-desert-berry-shows-rare-power-to-reverse-diabetes-in-mice\/","url_meta":{"origin":243,"position":5},"title":"Ancient Desert Berry Shows Rare Power to Reverse Diabetes in Mice","author":"SciChi","date":"July 25, 2025","format":false,"excerpt":"A crimson berry long prized by nomads in western China is offering new hope in the fight against type 2 diabetes. Scientists have shown that a natural extract from the fruit of Nitraria roborowskii Kom\u2014known locally as the \u201cdesert cherry\u201d\u2014can dramatically reduce blood sugar, restore insulin sensitivity, and protect organs\u2026","rel":"","context":"In &quot;Health&quot;","block_context":{"text":"Health","link":"https:\/\/scienceblog.com\/sciencechina\/category\/health\/"},"img":{"alt_text":"Nitraria roborowskii Kom","src":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/nitraria-37e12c3a-fcd6-4e31-ac60-1df56ac2965-resize-750.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/nitraria-37e12c3a-fcd6-4e31-ac60-1df56ac2965-resize-750.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/nitraria-37e12c3a-fcd6-4e31-ac60-1df56ac2965-resize-750.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/scienceblog.com\/sciencechina\/wp-content\/uploads\/sites\/16\/2025\/07\/nitraria-37e12c3a-fcd6-4e31-ac60-1df56ac2965-resize-750.jpeg?resize=700%2C400&ssl=1 2x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/posts\/243","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/users\/1299"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/comments?post=243"}],"version-history":[{"count":1,"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/posts\/243\/revisions"}],"predecessor-version":[{"id":245,"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/posts\/243\/revisions\/245"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/media\/244"}],"wp:attachment":[{"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/media?parent=243"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/categories?post=243"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceblog.com\/sciencechina\/wp-json\/wp\/v2\/tags?post=243"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}