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Transplant researchers stumble on possible treatment for lupus, blood cancers

Rapamycin, a drug approved for use in kidney transplant patients to prevent organ rejection, could also benefit patients with lupus and other autoimmune diseases as well as patients with blood cancers, such as acute myeloid leukemia, reports a team of researchers from the University of Pittsburgh and Justus-Liebig University in Giessen, Germany. Their conclusions, outlined in a paper to be published in the journal Blood and currently posted on the journal’s Web site (www.bloodjournal.org), were based on two key discoveries about rapamycin’s mechanisms.