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Where the fat’s at

In real estate, location is everything. The same might be said of lipids — those crucial cellular fats and oils that serve as building blocks for cells and as key energy sources for the body.
In a paper published in the September issue of…

Arthritis drug suppresses cancer development by stopping action of key protein

Researchers have, for the first time, identified the molecular pathway by which a commonly prescribed arthritis medication inhibits the growth of cancer. Before this study, scientists had linked use of celecoxib capsules (commonly known as Celebrex) to prevention of cancer, but the way in which the medication acted in cancer cells was unknown. Now, investigators have found that celecoxib capsules stop a key transcription factor known as Sp1 from turning on multiple genes in cancer cells known to be associated with cancer growth.