The effect of a high-fat meal on blood vessel walls can vary among individuals depending on factors such as their waist size and triglyceride levels, suggests new research at UC Davis.
The new research reinforces the link between belly fat, inflam…
A key mechanism that appears to contribute to blood vessel damage in people with diabetes has been identified by researchers at Washington University School of Medicine in St. Louis.
Blood vessel problems are a common diabetes complication. Many…
While the blood-brain barrier (BBB) protects the brain from harmful chemicals occurring naturally in the blood, it also obstructs the transport of drugs to the brain. In an article in Nature scientists at the Swedish medical university Karolinska In…
An article published this week in the journal Nature provides the first experimental evidence for an unusual molecular bonding mechanism that could explain how certain cells adhere to surfaces such as blood vessel walls under conditions of mechanical stress. Known as “catch bonds,” the adhesion mechanism displays surprising behavior, prolonging rather than shortening the lifetimes of bonds between specific molecules as increasing force is applied. Proposed theoretically nearly 15 years ago, catch bonds could help explain how the body regulates the activity of white blood cells, which must flow freely through blood vessels — yet bond to injury sites despite blood flow forces.