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Researchers discover new immune system molecule that can help or harm health

Researchers have identified a new member of the important B7 family of immune system “co-stimulators.” Co-stimulators are molecules that are capable of turning the immune system on or off — and in the process, profoundly affecting human health. Mayo Clinic researchers named this newest molecule B7-H4. It inhibits the action of T cells, the immune system warriors whose basic job is to attack invaders. Turning off T cells helps transplant patients accept foreign organs. But turning off T cells harms cancer patients — their tumors continue to grow without defensive attacks by T cells. The Mayo Clinic report appears in the June 17 issue of Immunity.

Optical biopsies on horizon using noninvasive biomedical imaging

A new imaging technique that could lead to optical biopsies without removal of tissue is being reported by biophysical scientists at Cornell and Harvard universities. The advance in biomedical imaging enables noninvasive microscopy scans through the surface of intact organs or body systems. Demonstrations of the new technique are producing images of diseased tissue at the cellular level with unprecedented detail.

Powerful nutritional supplement synthesized in lab at UCSB

One of the hottest nutritional supplements, currently manufactured by fermentation only in Japan, may eventually be synthesized in the United States thanks to research at the University of California, Santa Barbara. Bruce H. Lipshutz, professor of chemistry and biochemistry at UCSB, has developed a way to prepare coenzyme Q 10 (CoQ10 ) that he calls “short and sweet.” His method is patented and he is already talking to U.S. companies regarding potential commercialization. The process is economically competitive, using transition metal catalysts along the way, such as inexpensive nickel and cobalt complexes.

With Body Dysmorphic Disorder, Sufferers Only See Flaws

What society holds up as beautiful in men and women is often unrealistic, and in the modern age of computer-altered images and airbrushing, those ideals seem virtually unattainable for most people. The pressure to be perfect is especially difficult for people diagnosed with body dysmorphic disorder (BDD). These people are preoccupied with perceived or imagined flaws. While most people focus to some degree on their appearances, those with BDD are obsessed with their perceived flaws.

Study shows how key hormone hitches a lift round body

Structural analysis has revealed for the first time how a key messenger in the body’s chemical communication system hooks up with one of the proteins that delivers it to sites of action in the body. Using X-ray crystallography, scientists from Imperial College London and the University of Hawaii have identified the location of four binding sites on human serum albumin (HSA), the principal protein in blood plasma, to which the chemical messenger thyroxine attaches.

Researchers ID staph trick to kill off healthy cells

The method that Staphylococcus aureus (staph) infection uses to inactivate the body’s immune response and cause previously healthy B cells to commit suicide, is described for the first time by researchers at the University of California, San Diego (UCSD) School of Medicine. Normally, B cells mount an early defense against invading bacteria. From this immunologic experience, memory B cells are developed with the ability to quickly recognize these antigens and destroy the bacteria if they return in the future. When staph infections occur, however, this important process for immune defense can be corrupted.

New study finds yogurt may help burn body fat

While some calorie-conscious people may drop dairy products when they’re dieting, a new study suggests this strategy could backfire. Research presented today at the Experimental Biology conference reveals that yogurt may help turn up the body’s fat-burning ability ? making it easier to lose fat while maintaining lean muscle. The new study ? presented by Michael Zemel, Ph.D., professor of nutrition at the University of Tennessee ? found that individuals who included Yoplait Light as part of their weight loss plan lost significantly more weight compared to others who simply reduced calories. The yogurt eaters lost 22 percent more weight, 61 percent more body fat and 81 percent more trunkal (stomach) fat during the 12-week study.