Gene find raises hopes of new treatment for bowel cancer

A significant breakthrough by scientists at Cardiff University and the University of Edinburgh will enable new drugs to be developed, which could prevent bowel cancer. Researchers led by Professor Adrian Bird at Edinburgh and Professor Alan Clarke at Cardiff have discovered a gene, called MBD2, which is essential for bowel cancer cells to grow, but is dispensable in normal cells. The findings of the research, funded in part by the Wellcome Trust and published in the journal Nature Genetics, raise the possibility that drugs which inactivate MBD2 could prevent human bowel cancer without harming normal cells.