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This is your heart on drugs

The largest-ever study of cocaine users who suffered heart-related effects from taking the drug finds that a specially designed plan of emergency-room care for such patients can save both lives and money. Such plans have been in place for traditional chest pain patients for years, and many hospitals set aside part of their ERs to hold them for observation. But doctors have lacked criteria to help them decide how long to hold patients whose chest pain was caused by cocaine – even as millions of Americans are using the drug.

Cocaine harms brain’s ‘pleasure center’

New research results strongly suggest that cocaine bites the hand that feeds it, in essence, by harming or even killing the very brain cells that trigger the “high” that cocaine users feel. This most comprehensive description yet of cocaine-induced damage to key cells in the human brain’s dopamine “pleasure center” may help explain many aspects of cocaine addiction, and perhaps aid the development of anti-addiction drugs. It also could help scientists understand other disorders involving the same brain cells, including depression.