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You’ve know you’ve worked too long in a lab when…

My fellow scientists, you’re not alone in thinking “is it just me….”. Here is a short list of the few crazy things we do,...

Powerful new animal model for metastatic prostate cancer

Prostate cancer is the most common form of cancer in men. Affecting about 1 in 6 men, it is the second deadliest cancer. Research...

Neuron ‘claws’ in the brain enable flies to distinguish 1 scent...

Think of the smell of an orange, a lemon, and a grapefruit. Each has strong acidic notes mixed with sweetness. And yet each fresh, bright...

Neuroscientists find overlooked brain area is an important locus of depression

Cold Spring Harbor, NY -- A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL), Brookhaven National Laboratory (BNL) and UC San Diego (UCSD) has collected evidence suggesting that a previously overlooked portion of the brain could be a ...

CSHL scientists show in unprecedented detail how cortical nerve cells form...

Cold Spring Harbor, NY-- Newly published research led by Professor Z. Josh Huang, Ph.D., of Cold Spring Harbor Laboratory (CSHL) sheds important new light on how neurons in the developing brain make connections with one another. This activity, calle...

CSHL study finds that 2 non-coding RNAs trigger formation of a...

Cold Spring Harbor, N.Y. -- The nucleus of a cell, which houses the cell's DNA, is also home to many structures that are not bound by a membrane but nevertheless exist as distinct compartments. A team of Cold Spring Harbor Laboratory (CSHL) scienti...

Optical technique reveals unnexpected complexity in mammalian olfactory coding

Cold Spring Harbor, NY -- A team co-led by neuroscientists at Cold Spring Harbor Laboratory (CSHL) has shed light -- literally -- on circuitry underlying the olfactory system in mammals, giving us a new view of how that system may pull off some of i...

Mice that ‘smell’ light could help us better understand olfaction

CAMBRIDGE, Mass. -- Harvard University neurobiologists have created mice that can "smell" light, providing a potent new tool that could help researchers better understand the neural basis of olfaction. The work, described this week in the journal ...

Congressman, CSHL president urge quick action to reverse judicial embryonic stem...

Cold Spring Harbor, NY -- Against a backdrop of some of the world's most sophisticated biological research labs, Rep. Steve Israel (D-Huntington) this morning issued a challenge to his colleagues in Congress: immediately upon their return from summ...

Silent DNA architecture helps block cancer cell growth

Cancerous and precancerous cells can detect that they are abnormal and kill themselves, or remain alive indefinitely but cease proliferating, through two intrinsic processes called programmed cell death and cellular senescence. One goal of cancer chemotherapy is to help stimulate these potent antitumor processes. Researchers at Cold Spring Harbor Laboratory on Long Island have recently shown that by locking cancer cells into a permanent state in which they remain alive but can no longer proliferate, cellular senescence contributes to successful outcomes following cancer therapy. Now, the same group has uncovered a precise molecular mechanism that helps trigger the "stop growing" response of cells. The study is published in the June 13 issue of the journal Cell.

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