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TGen and Genomic Health Inc. discover genes affecting cancer drug

PHOENIX, Ariz. -- Jan. 13, 2011 -- Genomic research could help doctors better target a drug widely used to treat colorectal cancer patients, according to a study by Genomic Health Inc. (Nasdaq: GHDX) and the Translational Genomics Research Insti...

Nuclear receptors reveal possible interventions for cancer, obesity

HOUSTON, Jan. 10, 2011 -- Research with significant implications in the treatment and intervention of cancer and obesity has been published recently in two prestigious journals by University of Houston (UH) biochemist Dr. Jan-Åke Gustafsson....

Microsensors offer first look at whether cell mass affects growth rate

CHAMPAIGN, Ill. -- University of Illinois researchers are using a new kind of microsensor to answer one of the weightiest questions in biology -- the relationship between cell mass and growth rate. The team, led by electrical and computer engin...

Study sheds new light on how common painkillers prevent colon cancer

Building on earlier studies that have shown that common painkillers known as NSAIDs (non-steroidal anti-inflammatory drugs) can reduce the risk of colon cancer in healthy people, researchers at Dana-Farber Cancer Institute have identified a mechanism by which NSAIDs inhibit the development of colon cancer. Compared with normal cells, colorectal cancer cells have abnormally high levels of an immune system protein, IL-6. David Frank, MD, PhD, and his Dana-Farber colleagues have discovered that IL-6 triggers malignant growth by activating a protein called STAT1, which transmits signals that prevent the normal scheduled death of cells in the colon.

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