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coronary disease

No brain benefit from hormone therapy in women with heart disease

Another menopausal myth is challenged: Women with existing coronary disease do not realize improvement in their cognitive function as a result of taking the most common form of hormone replacement therapy, a UCSF study has found. Investigators followed more than 1000 women from ten US test sites for four years. Half took a placebo; the other half took hormone replacement therapy (HRT). Although other, smaller studies have shown an improvement, in the UCSF study the women who received HRT performed no better on standard tests of cognitive function than those who received placebo.

Hormones, Antioxidants Could Hurt Older Women with Heart Disease

A study sponsored by the National Institutes of Health has found that postmenopausal women with heart disease who took hormone therapy and high dose antioxidant vitamins ? either alone or in combination with hormones ? did not have fewer heart attacks, deaths, or progression of coronary disease. In fact, both treatments showed a potential for harm. Although the actual numbers of deaths in the study were small, participants taking both active hormones and vitamins had the highest death rate while participants on placebo versions of both treatments had the lowest death rate.