New Treatment Strategy for Crohn’s Disease Shows Early Promise

A preliminary study reports that enhancing the body’s innate immunity can improve symptoms of Crohn’s disease in 80 percent of patients with moderate to severe forms of the debilitating, inflammatory gastrointestinal disorder. Crohn’s disease is a chronic, lifelong condition, which affects about half a million people in the United States. Until now, the disease has been thought to result from an overactive immune system, and therapies have attempted to suppress, rather than enhance, the immune response. Therapies that suppress immunity improve symptoms in many Crohn’s disease patients, but researchers are looking for alternative treatments to help those who don’t respond.