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After 60 years, scientists uncover how thalidomide produced birth defects

More than 60 years after the drug thalidomide caused birth defects in thousands of children whose mothers took the drug while pregnant, scientists at...

Splice Variants Reveal Connections Among Autism Genes

A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology (CCSB) at the...

New computer model may aid personalized cancer care

Dana-Farber Cancer Institute scientists have developed a mathematical model to predict how a patient's tumor is likely to behave and which of several possible...

Scientists identify protein linking exercise to brain health

A protein that is increased by endurance exercise has been isolated and given to non-exercising mice, in which it turned on genes that promote...

Marriage linked to better cancer outcomes

People who are married when diagnosed with cancer live longer than those who are not, report researchers at Harvard-affiliated Dana-Farber Cancer Institute and Brigham...

Cancer vaccine begins Phase I clinical trials

A cross-disciplinary team of Harvard scientists, engineers, and clinicians announced today that they have begun a Phase I clinical trial of an implantable vaccine...

Researchers identify genetic mutation responsible for rare cancer

Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenstrom's macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause. ...

Researchers identify a novel therapeutic approach for liver cancer

BOSTON -- Cancer of the liver -- rare in the United States but the third-leading cause of cancer death worldwide -- can result from environmental exposures or infections like chronic hepatitis, but the link is poorly understood. Now, researchers...

New target found for aggressive cancer gene

Researchers have found a way to kill human cells hijacked by a genetic accelerator that puts cancer cells into overdrive: the Myc oncogene. The discovery reveals new drug targets for Myc-driven cancers, which tend to be particularly aggress...

Evolution reveals missing link between DNA and protein shape

Fifty years after the pioneering discovery that a protein's three-dimensional structure is determined solely by the sequence of its amino acids, an international team of researchers has taken a major step toward fulfilling the tantaliz...

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