After 60 years, scientists uncover how thalidomide produced birth defects
More than 60 years after the drug thalidomide caused birth defects in thousands of children whose mothers took the drug while pregnant, scientists at Dana-Farber … Read more
dana farber cancer institute
Splice Variants Reveal Connections Among Autism Genes
A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology (CCSB) at the Dana-Farber … Read more
New computer model may aid personalized cancer care
Dana-Farber Cancer Institute scientists have developed a mathematical model to predict how a patient’s tumor is likely to behave and which of several possible treatments … Read more
Scientists identify protein linking exercise to brain health
A protein that is increased by endurance exercise has been isolated and given to non-exercising mice, in which it turned on genes that promote brain … Read more
Marriage linked to better cancer outcomes
People who are married when diagnosed with cancer live longer than those who are not, report researchers at Harvard-affiliated Dana-Farber Cancer Institute and Brigham and … Read more
Cancer vaccine begins Phase I clinical trials
A cross-disciplinary team of Harvard scientists, engineers, and clinicians announced today that they have begun a Phase I clinical trial of an implantable vaccine to … Read more
Researchers identify genetic mutation responsible for rare cancer
Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenstrom’s macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause.
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Researchers identify a novel therapeutic approach for liver cancer
BOSTON — Cancer of the liver — rare in the United States but the third-leading cause of cancer death worldwide — can result from environmental exposures or infections like chronic hepatitis, but the link is poorly understood.
Now, researchers…
New target found for aggressive cancer gene
Researchers have found a way to kill human cells hijacked by a genetic accelerator that puts cancer cells into overdrive: the Myc oncogene. The discovery reveals new drug targets for Myc-driven cancers, which tend to be particularly aggress…
Evolution reveals missing link between DNA and protein shape
Fifty years after the pioneering discovery that a protein’s three-dimensional structure is determined solely by the sequence of its amino acids, an international team of researchers has taken a major step toward fulfilling the tantaliz…
Sweeping view of prostate cancer genome yields deep insights
NEW YORK, CAMBRIDGE, Mass., AND BOSTON (Feb. 9, 2011) — For the first time, researchers have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of t…
