dana farber cancer institute
Researchers identify genetic mutation responsible for rare cancer
Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenstrom’s macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause.
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Researchers identify a novel therapeutic approach for liver cancer
BOSTON — Cancer of the liver — rare in the United States but the third-leading cause of cancer death worldwide — can result from environmental exposures or infections like chronic hepatitis, but the link is poorly understood.
Now, researchers…
New target found for aggressive cancer gene
Researchers have found a way to kill human cells hijacked by a genetic accelerator that puts cancer cells into overdrive: the Myc oncogene. The discovery reveals new drug targets for Myc-driven cancers, which tend to be particularly aggress…
Evolution reveals missing link between DNA and protein shape
Fifty years after the pioneering discovery that a protein’s three-dimensional structure is determined solely by the sequence of its amino acids, an international team of researchers has taken a major step toward fulfilling the tantaliz…
Sweeping view of prostate cancer genome yields deep insights
NEW YORK, CAMBRIDGE, Mass., AND BOSTON (Feb. 9, 2011) — For the first time, researchers have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of t…
New clue to lupus: Failed autoimmune suppression mechanism
Bar Harbor, Maine — Researchers at Dana-Farber Cancer Institute in Cambridge, Mass., in collaboration with Jackson Laboratory scientists, have identified a regulatory defect that drives lupus.
Correcting the defect “may represent an effective t…
