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High-fat, high-calorie diet linked to pancreas cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center have found that mice made obese by high-calorie, high-fat diets develop abnormally high numbers of lesions known...

Snipping key nerves may help life-threatening heart rhythms

What do sweaty palms and abnormal heart rhythms have in common? Both can be initiated by the nervous system during an adrenaline-driven "flight-or-fight" stress...

Protein thought to protect against oxidative stress also promotes clogging of...

UCLA researchers have found that a protein that plays an important role in some antioxidant therapies may not be as effective due to additional mechanisms that cause it to promote atherosclerosis, or clogging of the arteries. Published in the Ja...

Study shows extreme form of pregnancy-related morning sickness could be genetic

Approximately 60,000 pregnant women are hospitalized each year due to hyperemesis gravidarum (HG), an extreme form of nausea and vomiting that endangers their lives and often forces them to reluctantly terminate their pregnancies. And for women...

Racial and ethnic disparities impact care for children with frequent ear...

Alexandria, VA -- Racial and ethnic disparities among children with frequent ear infections (FEI) significantly influence access to affordable healthcare, according to new research published in the November 2010 issue of Otolaryngology -- Head...

Doctors’ sense of mission, self-identity key in choice to work in...

Medical schools and clinics could boost the number of primary care physicians in medically underserved areas by selecting and encouraging students from these communities, who often exhibit a strong sense of responsibility for and identification with...

Study finds race, ethnicity impact access to care for children with...

Ear infections are one of the most common health problems for children, with most kids experiencing at least one by their third birthday. Annual costs in the United States alone are in the billions of dollars. When these infections are left untr...

UCLA study identifies genetic variation linked to lupus in Asian men

Genes reside along long chains of DNA called chromosomes. UCLA researchers have found that a variation in a gene on the sex chromosome X may enhance an immune response that leads to lupus in men. Systemic lupus erythematosus (SLE) is an a...

Common Acne Treatment Stops Blindness in Animal Model

Administering Accutane, a drug commonly used to treat acne, UCLA researchers have successfully stopped the accumulation of toxic pigments in the eyes of animals with a genetic defect similar to Stargardt's macular degeneration. The UCLA team gave a daily injection of Accutane to mimic the effect of constant light deprivation and the results proved dramatic. These toxic pigments, called lipofuscin, are responsible for the visual loss in patients with Stargardt's disease.

Pain killers may dissolve Alzheimer's disease plaques

In a breakthrough study, scientists have found that common painkillers such as ibuprofen and naproxen may actually dissolve the brain lesions -- or amyloid plaques -- that are one of the definitive hallmarks of Alzheimer's disease. The findings are reported in the March 31 issue of Neuroscience. Principal investigator Jorge R. Barrio, professor of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA, has used FDDNP, a new chemical marker developed in his laboratory at UCLA, to visually zero in on the brain lesions present in Alzheimer's disease. He discovered that common over-the-counter pain medications -- known as non-steroidal anti-inflammatory drugs -- bind to amyloid plaques, and may help dissolve existing plaques and prevent the formation of new ones.

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