A team led by Massachusetts General Hospital (MGH) researchers has developed a faster way to engineer synthetic enzymes that target specific DNA sequences for inactivation, repair or alteration. The report from the MGH Molecular Pathology Unit, bei…
Researchers at New York University’s Courant Institute of Mathematical Sciences have developed a novel algebraic model of DNA “hybridization,” a process central to most biotechnology devices that monitor changes in cell’s gene expression or charact…
Researchers from North Carolina State University have found a way to optimize the development of DNA self-assembling materials, which hold promise for technologies ranging from drug delivery to molecular sensors. The key to the advance is the disc…
Ames – An Iowa State University team of researchers has developed a type of hybrid proteins that can make double-strand DNA breaks at specific sites in living cells, possibly leading to better gene replacement and gene editing therapies.
Bing …
Yards of DNA are packed into cells by wrapping the DNA around proteins called nucleosomes. But that tight packing makes it hard for the cell’s machinery to get at the DNA code to read, copy or repair it. Now researchers at the University of California, Davis, have shown how two proteins form a molecular machine that shuffles the nucleosomes out of the way to expose the DNA double helix.