Enzymes Could Help Fight Drug-Resistant Bacteria

Researchers at Harvard say they have overcome a preliminary, yet critical, hurdle in the push to develop antibiotics against drug-resistant bacterial strains. Most attempts have been plagued by a lack of molecular tools for manipulating–and ultimately improving — the structure of naturally occurring antibiotics. The researchers report that they harnessed two enzymes, which work by adding sugars to a central molecular core, and used them to create new versions of two potent antibiotics, vancomycin and teicoplanin.