Ovarian cancer screening saves few lives

The best currently available screening tests can only slightly reduce ovarian cancer deaths. That is the conclusion of new research published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The results suggest that st…

Why so many antibodies fail to protect against HIV infection

DURHAM, NC — Researchers have been stymied for years over the fact that people infected with the AIDS virus do indeed produce antibodies in response to the pathogen — antibodies that turn out to be ineffective in blocking infection.
Now, sci…

Tiny molecules protect from the dangers of sex

DURHAM, N.C. — Pathogenic fungi have been found to protect themselves against unwanted genetic mutations during sexual reproduction, according to researchers at Duke University Medical Center. A gene-silencing pathway protects the fungal genome fr…

2 studies find new genetic links to ovarian cancer risk

DURHAM, N.C. — An international consortium of scientists has discovered new genetic variants in five regions of the genome that affect the risk of ovarian cancer in the general population, according to two separate studies published today (Sunday)…

Engineered Proteins Will Lead to ‘Synthetic Biology’

Biochemists have developed a computational method to design proteins that can specifically detect a wide array of chemicals from TNT to brain chemicals involved in neurological disorders. In a paper in the May 8, 2003, issue of the journal Nature, they demonstrate the breadth of their design method, and also that such sensor proteins can be re-incorporated into cells to activate cellular signaling and genetic pathways.

Diet, Exercise Together Effective in Controlling High Blood Pressure

New research suggests that an overhaul of dietary and fitness habits to help prevent or control high blood pressure is feasible with proper coaching, contrary to the theory that too many changes would be overwhelming and ineffective for most people. The best results in the study were achieved when weight loss, salt restriction and exercise were paired with the DASH (Dietary Approaches to Stop Hypertension) diet, which is rich in fruits, vegetables and low fat dairy products.

Growing Human Skin in Laboratory Can Prematurely Age Cells

Children who receive laboratory-expanded sheets of their own skin to cover severe burns are saved from certain death, but their new skin can have the cellular age of an 80 year old, according to a study at Duke University Medical Center. The process of growing small patches of human skin into larger sheets, called tissue engineering, makes cells divide so many times that the skin becomes prematurely aged at a cellular level.

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